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Hepatic myelopathy neurological complication of chronic liver disease: two case reports
BackgroundHepatic myelopathy is a very rare neurological complication of chronic liver disease. Patients habitually present with progressive pure...
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HTLV-1-associated myelopathy/tropical spastic paraplegia with sporadic late-onset nemaline myopathy: a case report
BackgroundSporadic late onset nemaline myopathy (SLONM) is a muscle disorder characterized by the presence of nemaline rods in muscle fibers. SLONM...
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The benefit of intravenous immune globulin in the treatment of delayed radiation myelopathy
Delayed radiation myelopathy (DRM) is a rare yet severe complication of radiotherapy. This condition has a progressive pattern that is often...
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HIV-associated neurocognitive disorder and HIV-associated myelopathy in a patient with a preserved CD4, but high viral load-a rarely reported phenomenon: a case report and literature review
BackgroundDespite widespread use of combination antiretroviral therapy (cART), HIV-associated neurocognitive disorder (HAND) and HIV-associated...
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Imbalanced IL10/TGF-β production by regulatory T-lymphocytes in patients with HTLV-1-associated myelopathy/ tropical spastic paraparesis
BackgroundHuman T-cell lymphotropic virus type 1 (HTLV-1), also denominated Human T-cell leukemia virus-1, induces immune activation and secretion of...
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Comparison of posterior muscle-preserving selective laminectomy and laminectomy with fusion for treating cervical spondylotic myelopathy: study protocol for a randomized controlled trial
BackgroundCervical spondylotic myelopathy (CSM) is the predominant cause of spinal cord dysfunction in the elderly. The patients are often frail and...
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Atypical HIV-vacuolar myelopathy: a case report
BackgroundHere, we report an atypical HIV-vacuolar myelopathy and search the available medical literature about atypical presentations of human...
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Radiological approach to non-compressive myelopathies
BackgroundMyelopathy, a pathological condition related to the spinal cord can broadly be categorized into compressive and non-compressive...
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Fibrocartilaginous embolism: a rare cause leading to spinal cord infarction?
PurposeFibrocartilaginous nucleus pulposus components herniation and embolism rarely causes acute ischaemic events involving the spinal cord. Few...
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Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) and Human Immunodeficiency virus infection: dilemmas in diagnosis and management: a case series
BackgroundMyelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently described autoimmune inflammatory disorder of the...
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HIV Neuropathy—a Review of Mechanisms, Diagnosis, and Treatment of Pain
Purpose of ReviewThis article is a systematic review of data from 2018 to 2020 regarding information from publications on epidemiologic, diagnostic,...
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Decoding dysregulated angiogenesis in HTLV-1 asymptomatic carriers compared to healthy individuals
Human T-cell lymphotropic virus type 1 (HTLV-1) is the first identified human retrovirus responsible for two significant diseases: HTLV-1-associated...
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Map of thrombogenesis in viral infections and viral-driven tumours
Viruses are pathogenic agents responsible for approximately 10% of all human cancers and significantly contribute to the global cancer burden. Until...
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Acquired ichthyosis: a clinical review
Acquired ichthyosis (AI) is a rare, nonhereditary cutaneous disorder that has been associated with numerous neoplastic, infectious, drugs, endocrine,...
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Spinal Cord Involvement and Brain Hemorrhage as an Atypical Presentation of Toxoplasmosis in a Patient with HIV
Central nervous system (CNS) toxoplasmosis is a well-known opportunistic infection in patients with AIDS. Spinal cord involvement and brain...
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Management of multiple sclerosis in older adults: review of current evidence and future perspectives
ImportanceThe prevalence of multiple sclerosis (MS) and aging MS patients is increasing worldwide. There is a need to better understand this MS...
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Seroprevalence of hepatitis E viral infection among apparently healthy personnels and patients with certain neurological disorders in Alexandria University Hospitals
IntroductionHepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis. There are thought to be 20 million infections per year in...
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Functional capacity of natural killer cells in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients
BackgroundNatural killer (NK) cells are part of the innate immune system and provide surveillance against viruses and cancers. The ability of NK...
