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Granulocyte–macrophage colony-stimulating factor-containing medium treatment after thawing improves blastocyst-transfer outcomes in the frozen- thawed blastocyst-transfer cycle
PurposeTo determine whether granulocyte–macrophage colony-stimulating factor (GM-CSF)-containing medium could improve embryo-transfer outcomes in...
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A case of granulocyte-colony-stimulating factor-producing gallbladder cancer with lymph node metastasis together with a literature review
The granulocyte-colony-stimulating factor (G-CSF) glycoprotein stimulates precursor cell proliferation and differentiation in the bone marrow....
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Interleukin-6 and granulocyte colony-stimulating factor as predictors of the prognosis of influenza-associated pneumonia
BackgroundPneumonia is a common complication of influenza and closely related to mortality in influenza patients. The present study examines...
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The Effect of Granulocyte Colony-Stimulating Factor on Endometrial Receptivity of Implantation Failure Mouse
AbstractThe purpose of this study was to investigate the effect of G-CSF on the endometrial receptivity of implantation failure mice. Sixty female...
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Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment
The macrophage colony-stimulating factor 1 (CSF1) is a chemokine essential for the survival, proliferation, and differentiation of mononuclear...
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Autoimmune Pulmonary Alveolar Proteinosis: A Review of Pathogenesis and Emerging Therapies
Purpose of ReviewAutoimmune pulmonary alveolar proteinosis is a heterogenous clinical syndrome of disordered surfactant clearance due to a...
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Shedding light on macrophage immunotherapy in lung cancer
The search for therapeutic options for lung cancer continues to advance, with rapid advances in the search for therapies to improve patient...
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Monocyte and macrophage function in respiratory viral infections
Pulmonary macrophages, such as tissue-resident alveolar and interstitial macrophages and recruited monocyte-derived macrophages, are the major...
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Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis
Acute lung injury (ALI) is one of the life-threatening complications of sepsis, and macrophage polarization plays a crucial role in the...
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Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease
BackgroundAdult-onset Still’s disease (AOSD) is a systemic autoinflammatory disease characterized by innate immune system activation, with a high...
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Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice
BackgroundTau protein serves a pro-inflammatory function in neuroinflammation. However, the role of tau in other inflammatory disorders such as...
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Tumor-associated macrophage-related strategies for glioma immunotherapy
High-grade glioma is one of the deadliest primary tumors of the central nervous system. Despite the many novel immunotherapies currently in...
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CD8 T cell-derived perforin regulates macrophage-mediated inflammation in a murine model of gout
ObjectivesGout is characterized by hyperuricemia and recurrent inflammatory episodes caused by intra-articular crystal deposition of monosodium urate...
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Lipotoxicity-polarised macrophage-derived exosomes regulate mitochondrial fitness through Miro1-mediated mitophagy inhibition and contribute to type 2 diabetes development in mice
Aims/hypothesisInsulin resistance is a major pathophysiological defect in type 2 diabetes and obesity. Numerous experimental and clinical studies...
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Macrophage migration inhibitory factor as a therapeutic target after traumatic spinal cord injury: a systematic review
PurposeMacrophages play an important role in mediating damage after Spinal cord injury (SCI) by secreting macrophage migration inhibitory factor...
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HER2/neu-based vaccination with li-Key hybrid, GM-CSF immunoadjuvant and trastuzumab as a potent triple-negative breast cancer treatment
PurposeConstituting 15 to 20% of breast cancer cases, the triple-negative subtype lacks effective treatments as being less responsive to...
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Insulin-like growth factor 1 associated with altered immune responses in preterm infants and pigs
BackgroundPreterm infants show low blood levels of insulin-like growth factor 1 (IGF-1), known to be negatively correlated with Interleukin-6 (IL-6)....
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CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice
Aims/hypothesisColony stimulating factor 1 (CSF1) promotes the proliferation, differentiation and survival of macrophages, which have been implicated...
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Granulocyte-Macrophage Colony-Stimulating Factor as a Therapeutic Target in Multiple Sclerosis
Multiple sclerosis is an inflammatory neurodegenerative disease of the central nervous system (CNS) and the most frequent cause of non-traumatic...