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Bilateral Simultaneous Primary Patellar Giant Cell Tumors
Giant cell tumor is a relatively frequent benign bone tumor; that is usually exhibited in the epiphyseo-metaphyseal region of long bones. Computed...
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Diagnosis and monitoring denosumab therapy of giant cell tumors of bone: radiologic-pathologic correlation
ObjectiveTo determine the value of CT and dynamic contrast-enhanced (DCE-)MRI for monitoring denosumab therapy of giant cell tumors of bone (GCTB) by...
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Bone and soft tissue tumors: clinicoradiologic-pathologic molecular-genetic correlation of novel fusion spindled, targetable-ovoid, giant-cell-rich, and round cell sarcomas
BackgroundNew entities in the classification of bone and soft tissue tumors have been identified by use of advanced molecular-genetic...
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Update of pediatric bone tumors: osteogenic tumors and osteoclastic giant cell-rich tumors
There are numerous bone tumors in the pediatric population, with imaging playing an essential role in diagnosis and management. Our understanding of...
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Diagnostic utility of CSF1 immunohistochemistry in tenosynovial giant cell tumor for differentiating from giant cell-rich tumors and tumor-like lesions of bone and soft tissue
BackgroundTenosynovial giant cell tumor (TSGCT) is a benign fibrohistiocytic tumor that affects the synovium of joints, bursa, and tendon sheaths and...
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Denosumab for giant cell tumors of bone from 2010 to 2022: a bibliometric analysis
Giant cell tumors of the bone (GCTB) are considered moderately malignant bone tumors. Denosumab, as a neoadjuvant therapy, provides new possibilities...
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Giant-cell-poor giant cell tumor of bone: report of two cases and literature review
Giant cell tumor of bone (GCTB) is a locally aggressive tumor that shows predilection for the metaphysis/epiphysis of long bones, with an incidence...
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Complications and prognosis of primary thoracic and lumbar giant cell tumors treated by total tumor resection
BackgroundSpinal giant cell tumor (SGCT) is a relatively rare primary tumor. En bloc resection is the preferred surgical procedure for it due to its...
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Xanthogranulomatous epithelial tumors and keratin-positive giant cell-rich soft tissue tumors: two aspects of a single entity with frequent HMGA2-NCOR2 fusions
Xanthogranulomatous epithelial tumor (XGET) and keratin-positive giant cell-rich soft tissue tumor with HMGA2-NCOR2 fusion (KPGCT) are two recently...
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Bone Tumors Evidence-based Approach in Diagnosis and Management
The book offers a comprehensive update on bone tumors and tumor like conditions including clinical, pathological and radiological features. It...
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Recurrent Giant Cell Tumour of Maxilla: A case report and review of literature
Giant cell tumors (GCTs) are rare, locally aggressive neoplasms that commonly affect the long bones. However, GCTs can also occur in the craniofacial...
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Recurrent Giant Cell Tumor of Sphenoid Bone: A Rare Finding
Giant Cell Tumors of the skull are rare and mostly occur in the middle cranial fossa. Radiological investigations serve as adjunct modalities;...
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Imaging characteristics of tenosynovial giant cell tumors on 18F-fluorodeoxyglucose positron emission tomography/computed tomography: a retrospective observational study
Background18 F-fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG-PET/CT) is useful for assessing location, metastasis,...
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Twofold Expression of Receptor Tyrosine Kinase 2 (ROR2) in Giant Cell Tumors of Bone: Outcome of a Case‒Control Study
Suppression or overexpression of transmembrane proteins of the Wnt family and receptor tyrosine kinases (ROR1 and ROR2) is implicated in the...
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Tenosynovial giant cell tumor: a case report
BackgroundThis case reports the synchronous diagnosis of two rare unrelated diseases; leiomyosarcoma and tenosynovial giant cell tumor of the knee....
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Giant Cell Tumor of Mandible : A Case Report
Giant cell tumor is locally aggressive primary benign neoplasm of bone with tendency of frequent recurrence, metastasis and malignant transformation....
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A Short Course of Preoperative Denosumab Injection Followed by Surgery in High-Risk Giant Cell Tumors of the Extremities: A Retrospective Study
Despite early promising results with denosumab treatment in giant cell tumor of bone (GCTB), recent studies have raised concerns about a high local...
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Increased [18F]FDG uptake of radiation-induced giant cells: a single-cell study in lung cancer models
Positron emission tomography (PET), a cornerstone in cancer diagnosis and treatment monitoring, relies on the enhanced uptake of fluorodeoxyglucose ([
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Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis
BackgroundWe examined the impact of bisphosphonates as adjuvant therapy on the recurrence of giant cell bone tumors and the impact of various tumor...
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Salvaging the Unsalvageable Giant Cell Tumors of Bone: The ‘Longitudinal Sandwich Technique’
Management of Campanacci Grade III Giant Cell Tumors of bone (GCT) is challenging. Although selected cases of Grade III GCTs can still be managed...
