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Efficacy and Tolerability of Adjunctive Brivaracetam in Patients with Focal-Onset Seizures on Specific Concomitant Antiseizure Medications: Pooled Analysis of Double-Blind, Placebo-Controlled Trials
IntroductionThis article aimed to assess the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with focal-onset seizures on...
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Focal seizures during adrenocorticotropic hormone therapy in a school-aged boy: a case report
BackgroundAdrenocorticotropic hormone therapy for infantile spasms, including West syndrome, has been previously reported to induce seizures. We...
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Effect of Cenobamate on Cognition in Patients with Drug-Resistant Epilepsy with Focal Onset Seizures: An Exploratory Study
Background and ObjectiveMost second and third generation antiseizure medications (ASMs) are associated with cognitive adverse events, which are a...
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Safety and Efficacy of Cenobamate for the Treatment of Focal Seizures in Older Patients: Post Hoc Analysis of a Phase III, Multicenter, Open-Label Study
BackgroundCenobamate is an antiseizure medication (ASM) approved in the US and Europe for the treatment of uncontrolled focal seizures.
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Absence seizures in lesion-related epilepsy
BackgroundIn the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures...
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Clinical Characteristics and Prognostic Significance of Subclinical Seizures in Focal Epilepsy: A Retrospective Study
IntroductionThe aim was to evaluate the clinical characteristics and prognostic significance of subclinical seizures (SCSs) on scalp...
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Treatment of Seizures in the Neonate: Special Report From the ILAE Task Force on Neonatal Seizures, 2022
The International League Against Epilepsy (ILAE) task force on neonatal seizures has recently published draft guidelines and consensus-based...
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Neonatal seizures during extra corporeal membrane oxygenation support
To evaluate EEG monitoring during neonatal ECMO and to identify any correlations between seizure detection to abnormal neuroimaging. Eight-year,...
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Self-limited focal epilepsies of childhood syndromes (SeLFEs)—an overview
Self-limited focal epilepsies of childhood syndromes (SeLFEs) comprise a group of disorders historically also widely known as “idiopathic focal...
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Technical case report: intractable focal seizures related to bifrontal transmantle heterotopia subserving peculiar homotopic motor distribution treated by responsive neurostimulation therapy
NeuroPace responsive neurostimulation (RNS ® ) therapy was used in a case of intractable focal epilepsy with bifrontal transmantle heterotopia...
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Brivaracetam as Early Add-On Treatment in Patients with Focal Seizures: A Retrospective, Multicenter, Real-World Study
IntroductionIn randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Most...
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Stroke-related early seizures: clinical and neurophysiological study in a sample of Egyptian population
BackgroundAvailable data collected from patients of different types of acute cerebrovascular strokes can detect risk factors, clinical data...
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Adjunctive Brivaracetam in Older Patients with Focal Seizures: Evidence from the BRIVAracetam add‑on First Italian netwoRk Study (BRIVAFIRST)
BackgroundThe management of epilepsy in older adults has become part of daily practice because of an aging population. Older patients with epilepsy...
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Co-existence of self-limited focal epilepsies of childhood (SelFEC) and epileptiform discharges in the context of SelFEC in children with structural focal epilepsies and in children with brain lesions
The co-occurrence of self-limited focal epilepsies of childhood (SelFEC) and epileptiform discharges in the context of SelFEC (EDSelFEC) in children...
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Dural arteriovenous fistula presenting with recurrent focal status epilepticus and lateralised periodic epileptiform discharges
BackgroundDural arteriovenous fistulae (dAVF) are relatively infrequently encountered, and status epilepticus (SE) and lateralised periodic...
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Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis
BackgroundBrivaracetam (BRV), cenobamate (CNB), eslicarbazepine acetate (ESL), lacosamide (LCM) and perampanel (PER) are antiseizure medications...
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Predictive factors for post operative seizures following meningioma resection in patients without preoperative seizures: a multicenter retrospective analysis
PurposeMeningiomas are the most common primary brain tumor and represent 35% of all intracranial neoplasms. However, in the early post-operative...
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Withdrawal seizures vs on-medication seizures: an intracranial EEG recording case report
BackgroundIt has long been an interesting question of whether withdrawal seizures in epileptic patients differ from habitual seizures in terms of...
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The well responsiveness of drug-resistant focal seizures in anti-AMPA2 receptor encephalitis to perampanel treatment
Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis is an anti-neuronal surface antigen autoimmune encephalitis...
