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Multivariate analysis of seizure outcomes after resective surgery for focal epilepsy: a single-center study on 833 patients
The predictors of seizure outcomes after resective surgery for focal epilepsy, for an update on the features of good and poor outcomes, are...
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Sentinel seizure heralding Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease
BackgroundIsolated seizure as a manifestation of myelin oligodendrocyte antibody-associated disease (MOGAD) has rarely been reported previously.
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Short post-injection seizure duration is associated with reduced power of ictal brain perfusion SPECT to lateralize the seizure onset zone
BackgroundThe aim of this study was to assess the impact of the post-injection electrical seizure duration on the identification of the seizure onset...
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Pre-operative predictors of post-operative seizure control in low-grade glioma: a systematic review and meta-analysis
As many as 80% of low-grade gliomas (LGGs) present with seizures, negatively impacting quality of life. While seizures are associated with gliomas...
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Seizure semiology and predictors of outcomes in Chinese patients with glutamic acid decarboxylase antibody-associated neurological syndrome
BackgroundIn the current study, seizure semiology and potential predictive factors of seizure outcomes in glutamic acid decarboxylase antibody (GAD...
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Seizure clusters: diagnostic and therapeutic advances
Epilepsy affects 45.9 million people globally. For individuals with epilepsy who continue to have seizures, up to half experience seizure clusters....
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Dural arteriovenous fistula presenting with recurrent focal status epilepticus and lateralised periodic epileptiform discharges
BackgroundDural arteriovenous fistulae (dAVF) are relatively infrequently encountered, and status epilepticus (SE) and lateralised periodic...
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Effectiveness and Safety of Adjunctive Cenobamate in People with Focal-Onset Epilepsy: Evidence from the First Interim Analysis of the BLESS Study
IntroductionDespite new anti-seizure medications (ASMs) being introduced into clinical practice, about one-third of people with epilepsy do not reach...
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Benzodiazepines for the Treatment of Seizure Clusters
Patients with epilepsy may experience seizure clusters, which are described by the US Food and Drug Administration (FDA) as intermittent, stereotypic...
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Early identification of seizure freedom with medical treatment in patients with mesial temporal lobe epilepsy and hippocampal sclerosis
BackgroundMesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is usually associated with a poor response to antiseizure medications....
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Hippocampal magnetic resonance imaging in focal onset seizure with impaired awareness—descriptive study from tertiary care centre in southern part of India
BackgroundTemporal lobe epilepsy is the most common type of focal onset seizure. Focal onset seizure with impaired awareness, previously known as...
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Towards trustworthy seizure onset detection using workflow notes
A major barrier to deploying healthcare AI is trustworthiness. One form of trustworthiness is a model’s robustness across subgroups: while models may...
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Demographic and clinical characteristics, seizure disorders, and antiepileptic drug usage in different types of corpus callosum disorders: a comparative study in children
BackgroundThis study aimed to investigate the demographic and clinical characteristics, types of seizure disorders, and antiepileptic drug usage...
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High-precision stereotactic irradiation for focal drug-resistant epilepsy versus standard treatment: a randomized waitlist-controlled trial (the PRECISION trial)
IntroductionThe standard treatment for patients with focal drug-resistant epilepsy (DRE) who are not eligible for open brain surgery is the...
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Psychiatric implications of anti-seizure medications in epileptic population
Background and objectiveEpilepsy is a prevalent neurological disorder that affects a significant number of individuals globally. This condition is...
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Genetics of nonlesional focal epilepsy in adults and surgical implications
Nonlesional focal epilepsies (nlFE) represent a heterogenous group of syndromes. They encompass self-limited focal epilepsies of childhood and youth,...
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Acute Symptomatic Seizures and Risk of Seizure Recurrence in Patients with Anti-NMDAR, Anti-LGI1, and Anti-GABABR Encephalitis
AimsTo analyze the clinical characteristics of acute symptomatic seizures and predict the risk factors for seizure recurrence in patients with...
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Efficacy and Tolerability of Adjunctive Brivaracetam in Patients with Focal-Onset Seizures on Specific Concomitant Antiseizure Medications: Pooled Analysis of Double-Blind, Placebo-Controlled Trials
IntroductionThis article aimed to assess the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with focal-onset seizures on...
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First seizure in elderly patients: Need to treat? Evidence from a retrospective study
BackgroundThe risk of seizure recurrence after a first unprovoked epileptic seizure is reported to be approximately 40%. Little is known about the...
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Updates on Anti-seizure Medication Use in Pregnancy
Purpose of ReviewCare of people with epilepsy and gestational capacity throughout pregnancy involves weighing risks of seizures with the known risks...
