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Neonatal magnesium levels are safe after maternal MgSO4 administration: a comparison between unexposed preterm neonates and neonates exposed for fetal neuroprotection or maternal eclampsia prevention—a cohort study
To objective of this study was to compare neonatal magnesemia in the first 15 days of neonatal life between three groups: a control group not exposed...
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The atypical antidepressant tianeptine confers neuroprotection against oxygen–glucose deprivation
Proregenerative and neuroprotective effects of antidepressants are an important topic of inquiry in neuropsychiatric research. Oxygen–glucose...
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Effects of fetal growth restriction on the perinatal neurovascular unit and possible treatment targets
AbstractThe neurovascular unit (NVU) within the brain is a multicellular unit that synergistically acts to maintain blood–brain barrier function and...
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Neuroprotective effects of maternal melatonin administration in early-onset placental insufficiency and fetal growth restriction
BackgroundEarly-onset fetal growth restriction (FGR) is associated with adverse outcomes. We hypothesised that maternal melatonin administration will...
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Evaluation of systemic immune-inflammation index for predicting late-onset fetal growth restriction
IntroductionTo determine a cut-off value for systemic immune-inflammation index (SII) (neutrophil × platelet/lymphocyte) in the prediction of fetal...
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Fetal aortic isthmus Doppler assessment to predict the adverse perinatal outcomes associated with fetal growth restriction: systematic review and meta-analysis
PurposeFetal growth restriction (FGR) management and delivery planning is based on a multimodal approach. This meta-analysis aimed to evaluate the...
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Fetal, Preterm, and Term Neonate Exposure to Remifentanil: A Systematic Review of Efficacy and Safety
BackgroundOwing to its pharmacodynamic properties, especially the rapid onset and short duration of its action, the use of remifentanil in obstetric...
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Childhood outcomes after maternal antenatal sildenafil treatment for severe early-onset fetal growth restriction: a randomized trial (STRIDER NZAus)
In this follow-up at 2.5 years of children from the STRIDER NZAus Trial ( N = 112), in which women with singleton pregnancies affected by severe early...
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Impact of early-onset fetal growth restriction on the neurodevelopmental outcome of very preterm infants at 24 months: a retrospective cohort study
BackgroundThe association between fetal growth restriction (FGR) and childhood neurodevelopmental delay is unclear and the evidence available to the...
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Efficacy of Antenatal Magnesium Sulfate for Neuroprotection in Extreme Prematurity: A Comparative Observational Study
BackgroundSurvival of preterm infants has improved drastically. In addition to significant contribution to neonatal mortality, impact of prematurity...
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Successful amnioinfusion for severe fetal growth restriction with umbilical cord complications: two case reports
BackgroundThere is no established treatment for fetal growth restriction during pregnancy. We report two cases that represent an example of an...
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A prospective, double-blinded cohort study using quantitative fetal fibronectin testing in symptomatic women for the prediction of spontaneous preterm delivery
BackgroundSpontaneous preterm birth (PTB) affects 6.5% of deliveries in Hong Kong. Quantitative fetal fibronectin (fFN) is under-utilised as a test...
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Maternal neuropeptide galanin levels in pregnancies with intra-uterine growth restriction (IUGR): neurohormonal regulation of fetal weight
AimGalanin is a neuroendocrine peptide with diverse biological actions in humans. Here, we evaluated plasma galanin levels in pregnant women with...
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A Comparison of Obstetric Interventions and Outcomes Between Black and White Patients at an Urban Tertiary Medical Center
The objective of the study is to evaluate whether rates of selected labor and delivery interventions and severe maternal morbidity (SMM) differ...
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Oral melatonin as a new tool for neuroprotection in preterm newborns: study protocol for a randomized controlled trial
BackgroundPrevention of neurodevelopmental impairment due to preterm birth is a major health challenge. Despite advanced obstetric and neonatal care,...
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Maternal Progesterone Treatment Reduces Maternal Inflammation-Induced Fetal Brain Injury in a Mouse Model of Preterm Birth
Maternal natural vaginal progesterone (nVP) administration has been shown to reduce the risk of preterm birth (PTB). The largest randomized trial of...
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Neonatal outcomes in the surgical management of placenta accreta spectrum disorders: a retrospective single-center observational study from 468 Vietnamese pregnancies beyond 28 weeks of gestation
BackgroundPlacenta accreta spectrum disorders (PASDs) increase the mortality rate for mothers and newborns over a decade. Thus, the purpose of the...
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Stem cell therapies in stroke rehabilitation: a narrative review of current strategies and future prospects
This paper explores the potential of stem cell therapies in revolutionising stroke recovery, addressing the limitations of current treatments and...
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Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature
ObjectiveTo evaluate impact of a quality improvement (QI) outreach education on incidence of acute brain injury in transported premature neonates.
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