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Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature

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Abstract

Objective

To evaluate impact of a quality improvement (QI) outreach education on incidence of acute brain injury in transported premature neonates.

Study design

Neonates born at <33 weeks gestation outside the tertiary center were included. The QI intervention was a combination of neuroprotection care bundle, in-person visits, and communication system improvement. Descriptive and regression (adjusting for Gestational Age, Birth Weight, Gender, and antenatal steroids, Mode of delivery, Apgars at 5 minutes, Prophylactic indomethacin, PDA, and Inotropes use) analyses were performed. The primary outcome was a composite of death and/or severe brain injury on cranial ultrasound using a validated classification.

Results

181 neonates studied (93 before and 88 after). The rate and adjusted odds of death and/or severe brain injury reduced significantly post intervention (30% vs 15%) and (AOR 0.36, 95%CI, 0.15–0.85, P = 0.02) respectively.

Conclusion

Implementation of outreach education targeting neuroprotection can reduce acute brain injury in transported premature neonates.

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Fig. 1
Fig. 2: Interrupted Time Series (ITS).

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Authors and Affiliations

  1. Department of Pediatrics, Section of Neonatology, University of Calgary, Calgary, Alberta, Canada

    Khorshid Mohammad, Sarfaraz Momin, Prashanth Murthy, Hussein Zein, Ayman Abou Mehrem, Anirban Ghosh, Artem Javadyan, Essa Al Awad, Sujith Kumar Reddy Gurram Venkata, Renee Paul, Bryan Rombough, Leah Bolderheij, Salma Dossani, John Montpetit, Peace Eshemokhai, Elsa Fiedrich & Sumesh Thomas

  2. Department of Diagnostic Imaging, Division of Neuroradiology, University of Calgary, Calgary, Alberta, Canada

    James N. Scott

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  1. Khorshid Mohammad
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  4. Hussein Zein
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Contributions

Substantial contributions to conception and design, acquisition of data: KM. Analysis & interpretation of data, drafting the article: SM, KM, ST. Develo** and implementing the bundle: KM, PM, ST, HZ, LL. Cranial ultrasounds classification: JNS. Drafting the article or revising it critically for important intellectual content: All authors. Final approval of the version to be published: All authors.

Corresponding author

Correspondence to Khorshid Mohammad.

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Mohammad, K., Momin, S., Murthy, P. et al. Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature. J Perinatol 42, 1368–1373 (2022). https://doi.org/10.1038/s41372-022-01409-2

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