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Is unicentric familial papillary thyroid microcarcinoma different from multicentric?
BackgroundFamilial papillary thyroid microcarcinoma (FPTMC) appears to be more aggressive than sporadic papillary thyroid microcarcinoma (SPTMC)....
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Medullary Thyroid Carcinoma: A Single Institute Experience
Medullary thyroid carcinoma is a rare tumour that is anatomically located in the thyroid gland but is functionally a neuroendocrine tumour. It is...
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Current Surveillance and Treatment Guidelines for Thyroid Carcinoma
Purpose of ReviewAlthough thyroid nodules are often a common finding during examination of the thyroid gland, with a prevalence of approximately 5%...
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Unforeseen Complication in a Patient with Recurrent Papillary Carcinoma Thyroid
The incidence of thyroid papillary cancer is approximately 13.5 per 100,000.Papillary thyroid carcinoma (PTC) is usually associated with favorable...
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Cribriform Morular Thyroid Carcinoma – Ultimobranchial Pouch-Related? Deep Molecular Insights of a Unique Case
A 44-year-old female patient with a familial adenomatous polyposis (FAP) was diagnosed with a cribriform morular thyroid carcinoma (CMTC). We...
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Familial Non-Medullary Thyroid Carcinoma in Pediatric Age: Our Surgical Experience
BackgroundThe purpose of the article was to evaluate the existence of significant clinical, pathological and prognostic differences between familial...
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Poorly differentiated papillary thyroid carcinoma in a 5-year-old girl: a case report
BackgroundThe incidence of thyroid cancer has been increasing among the population less than 20 years of age, especially during the second decade of...
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HRAS-mutated primary thyroid malignant melanoma or medullary thyroid carcinoma with melanocytic dedifferentiation? A singular case with an ontogeny–phylogeny quandary
Melanotic pigment in the thyroid is practically synonymous with chronic minocycline therapy and rare cases of melanotic medullary thyroid carcinoma....
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Biological behavior of familial papillary thyroid microcarcinoma: Spanish multicenter study
PurposeFamilial papillary thyroid microcarcinoma (FPTMC) can present a more aggressive behavior than the sporadic microcarcinoma. However, few...
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Distant Metastasis as the First Presentation of Thyroid Carcinoma
IntroductionThyroid carcinoma is the most common endocrine cancer which may manifest with unusual presentations. We addressed distant metastases as...
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De novo familial adenomatous polyposis associated thyroid cancer with a c.2929delG frameshift deletion mutation in APC: a case report and literature review
BackgroundGermline mutations in the APC gene located on chromosome 5q 21–22 can lead to familial adenomatous polyposis (FAP) and the development of...
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Cribriform morular thyroid carcinoma: a case report with pathological, immunohistochemical, and molecular findings suggesting an origin from follicular cells (or their endodermal precursors)
Cribriform morular thyroid carcinoma (CMTC) is a rare malignant thyroid tumor with a peculiar growth pattern secondary to permanent activation of the...
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International medullary thyroid carcinoma grading system: an Indian tertiary care centre experience
IntroductionMedullary carcinoma (MTC) is a rare neuroendocrine thyroid neoplasm. The international medullary thyroid carcinoma grading scheme...
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High Fatty Acid-Binding Protein 4 Expression Associated with Favorable Clinical Characteristics and Prognosis in Papillary Thyroid Carcinoma
Fatty acid-binding protein 4 ( FABP4 ), a fatty acid transporter that coordinates lipid metabolism, is reported to exert a tumorigenic role in certain...
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Wnt/β-catenin signaling is a therapeutic target in anaplastic thyroid carcinoma
BackgroundAnaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy that has consistently shown Wnt/β-catenin (canonical) signaling...
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Next-generation sequencing identified that RET variation associates with lymph node metastasis and the immune microenvironment in thyroid papillary carcinoma
BackgroundTo date, although most thyroid carcinoma (THCA) achieves an excellent prognosis, some patients experience a rapid progression episode, even...
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A computational approach to assessing the prognostic implications of BRAF and RAS mutations in patients with papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer, posing a growing clinical challenge. PTC exhibits two age-related peaks, with...
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Update on C-Cell Neuroendocrine Neoplasm: Prognostic and Predictive Histopathologic and Molecular Features of Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC) is a C-cell-derived epithelial neuroendocrine neoplasm. With the exception of rare examples, most are...
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Outcome and complications after surgery for thyroid carcinoma in pediatric age—an evaluation of practice
ObjectivesTo discuss management protocol, surgical complications, and outcomes of thyroid carcinoma in children.
MethodsWe performed a retrospective...
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Genomics and Epigenomics of Medullary Thyroid Carcinoma: From Sporadic Disease to Familial Manifestations
Our understanding of the genomics and epigenomics of medullary thyroid carcinoma (MTC) has advanced since the initial recognition of RET as a driver...
