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Ovarian seromucinous carcinoma: an independent epithelial ovarian cancer?
Background2020 World Health Organization Classification of Female Genital Tumors removed ovarian seromucinous carcinoma as a distinct entity and...
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Characterization of tumour microenvironment reprogramming reveals invasion in epithelial ovarian carcinoma
BackgroundPatients with epithelial ovarian carcinoma (EOC) are usually diagnosed at an advanced stage with tumour cell invasion. However, identifying...
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Seeing beyond the tumor: computed tomography image-based radiomic analysis helps identify ovarian clear cell carcinoma subtype in epithelial ovarian cancer
ObjectiveTo develop and validate a model that can preoperatively identify the ovarian clear cell carcinoma (OCCC) subtype in epithelial ovarian...
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An unusual case of a tibial metastasis as the first clinical presentation of a serous papillary carcinoma of the ovarian epithelial type of the testis
Among testicular neoplasms, ovarian-type epithelial tumors constitute an exceedingly rare group, with only a few cases reported in the literature. We...
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The stromal tumor-infiltrating lymphocytes, cancer stemness, epithelial-mesenchymal transition, and B7-H4 expression in ovarian serous carcinoma
BackgroundB7-H4 is expressed in various types of cancers and its expression inversely correlates with the degree of tumor-infiltrating lymphocytes...
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Global epidemiology of epithelial ovarian cancer
Globally, ovarian cancer is the eighth most common cancer in women, accounting for an estimated 3.7% of cases and 4.7% of cancer deaths in 2020....
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Polyploidy, EZH2 upregulation, and transformation in cytomegalovirus-infected human ovarian epithelial cells
Human cytomegalovirus (HCMV) infection has been implicated in epithelial ovarian cancer (OC). Polyploidy giant cancer cells (PGCCs) have been...
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Heterogeneity and treatment landscape of ovarian carcinoma
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and anatomical levels, both spatially and temporally. This...
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Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
BackgroundThe epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression....
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Immunohistochemical expression of PRAME in 485 cases of epithelial tubo-ovarian tumors
Preferentially expressed antigen of melanoma (PRAME) is a cancer/testis antigen selectively expressed in somatic tissues and various solid malignant...
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Cytoreductive Surgery with HIPEC as Primary Treatment for Advanced Epithelial Ovarian Carcinoma: Upfront or Interval—ISPSM Collaborative Study
Cytoreductive surgery with HIPEC has shown promising results in the interval setting of advanced epithelial ovarian cancer. Its role in upfront...
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Effect of different treatment modalities on the prognosis of stage IV epithelial ovarian cancer: analysis of the SEER database
BackgroundThe prognosis of advanced ovarian cancer is often poor. Although there are several treatment options for stage IV epithelial ovarian...
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Role of protein tyrosine phosphatase receptor type M in epithelial ovarian cancer progression
BackgroundEpithelial ovarian cancer (EOC) is often diagnosed at advanced stages with low survival rates. Protein tyrosine phosphatase receptor type M...
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Malignant Transformation of Ovarian Mature Cystic Teratoma into Squamous Cell Carcinoma: A Case Report
IntroductionMature cystic teratoma (MCT), a benign tumour commonly called the dermoid cyst, is the most common type of ovarian germ cell tumours....
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The Clinicopathological and Prognostic Values of Chemotherapy Response Score in Tubo-Ovarian High-Grade Serous Carcinoma
PurposeTubo-ovarian high-grade serous carcinoma is one of the aggressive ovarian tumors. Neoadjuvant chemotherapy has been used in managing the...
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Diagnostic value of plasma-derived exosomal miR-223 for epithelial ovarian cancer
ObjectivesTo evaluate the diagnostic value of plasma exosomal miR-223 and its combination with CA125 for the diagnosis of early-stage epithelial...
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SLFN5 promotes reversible epithelial and mesenchymal transformation in ovarian cancer
Ovarian cancer is a disease with increasing incidence worldwide, and there is an urgent need for chemotherapy and biological targeted therapy....
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Tumor metabolism rewiring in epithelial ovarian cancer
The mortality rate of epithelial ovarian cancer (EOC) remains the first in malignant tumors of the female reproductive system. The characteristics of...
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Ovarian endometrioid carcinoma with a sex cord-like pattern: a morphological, immunohistochemical, and molecular analysis
Sex cord-like endometrioid carcinoma (SCLEC) is an uncommon entity which may constitute a diagnostic challenge. This study aimed to perform a...
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Role of magnetic resonance imaging to differentiate between borderline and malignant serous epithelial ovarian tumors
PurposeWe aimed to differentiate serous borderline ovarian tumors (SBOT) from serous epithelial ovarian carcinomas (SEOC) using morphological and...
