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Effective treatment of NR2F1-related epilepsy with perampanel
BackgroundNR2F1 mutations are associated with Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Although ~ 46.7% of BBSOAS patients present...
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Does SANAD II help with gender-specific problems in epilepsy treatment?—English Version
Gender-specific differences in the treatment of epilepsy are a continuous challenge in the choice of treatment. Earlier studies on antiseizure...
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Narrative Review of Brivaracetam: Preclinical Profile and Clinical Benefits in the Treatment of Patients with Epilepsy
One third of patients with epilepsy will continue to have uncontrolled seizures despite treatment with antiseizure medications (ASMs). There is...
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Consensus on pediatric epilepsy surgery for young children: an investigation by the China Association Against Epilepsy task force on epilepsy surgery
Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy. Nonetheless, there is a substantial gap...
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Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed
BackgroundThere is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of...
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Structural connectivity as a predictive factor for responsiveness to levetiracetam treatment in epilepsy
PurposeTo investigate whether structural connectivity or glymphatic system function is a potential predictive factor for levetiracetam (LEV) response...
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Epilepsy Treatment in Patients with Heart Disease
Purpose of reviewThis review highlights issues pertaining to the treatment of seizures in patients with cardiac disease. These fall into two...
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The osteoplastic flap for pediatric temporal lobe epilepsy treatment: step-by-step guide and technical nuances
The osteoplastic flap is an under-utilized craniotomy approach in pediatric temporal lobe epilepsy treatment. By preserving the myofascial attachment...
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Robot-assisted treatment of secondary epilepsy caused by parasitic infection: a case report
BackgroundCerebral sparganosis represents the most severe manifestation of sparganosis, with a relatively low global incidence. For cases of...
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Diagnosis and Treatment of Poststroke Epilepsy: Where Do We Stand?
Purpose of ReviewStroke is the most common cause of seizures and epilepsy in older adults. This educational paper aims to give an update on current...
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Surgical treatment of cavernous malformation-related epilepsy in children: case series, systematic review, and meta-analysis
Objective : Cerebral cavernous malformations (CCMs) are cerebral vascular lesions that occasionally occur with seizures. We present a retrospective...
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Clinical and economic implications of epilepsy management across treatment lines in Spain: a real-life database analysis
BackgroundEpilepsy is a chronic brain disease characterized by recurrent seizures. We investigated real-world management of epilepsy across treatment...
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Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies
Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may...
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New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development
The inhibitory neurotransmitter γ-aminobutyric acid (GABA) plays an important role in the modulation of neuronal excitability, and a disruption of...
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Patient preferences for epilepsy treatment: a systematic review of discrete choice experimental studies
BackgroundThis review aimed to 1) identify and assess the quality of discrete choice experiments (DCEs) examining preferences related to epilepsy...
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Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes
Seizures and epilepsy can result from various aetiologies, yet the underlying cause of several epileptic syndromes remains unclear. In that regard,...
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Practical Questions About Rescue Medications for Acute Treatment of Seizure Clusters in Children and Adolescents with Epilepsy in the USA: Expanding Treatment Options to Address Unmet Needs
Epilepsy is a common pediatric neurological condition, affecting approximately 470,000 children in the USA and having a prevalence of 0.9% in the...
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Surgical Treatment of Drug-Resistant Generalized Epilepsy
Purpose of ReviewTo summarize current evidence and recent developments in the surgical treatment of drug-resistant generalized epilepsy.
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Treatment of Epilepsy in the Setting of Cognitive Decline in Older Adults
Purpose of ReviewDiscuss the state of the literature for the treatment of comorbid epilepsy and cognitive dysfunction, specifically focusing on the...
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Treatment Outcomes of Newly Diagnosed Epilepsy: A Systematic Review and Meta-analysis
Background and ObjectivesUnderstanding the multi-faceted treatment outcomes of newly diagnosed epilepsy is critical for develo** rational...