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  1. Effective treatment of NR2F1-related epilepsy with perampanel

    Background

    NR2F1 mutations are associated with Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Although ~ 46.7% of BBSOAS patients present...

    **ao Li, Kai Gao, ... Yuwu Jiang in Acta Epileptologica
    Article Open access 24 January 2024
  2. Does SANAD II help with gender-specific problems in epilepsy treatment?—English Version

    Gender-specific differences in the treatment of epilepsy are a continuous challenge in the choice of treatment. Earlier studies on antiseizure...

    B. Tettenborn, C. Baumgartner, ... B. J. Steinhoff in Clinical Epileptology
    Article Open access 01 November 2023
  3. Narrative Review of Brivaracetam: Preclinical Profile and Clinical Benefits in the Treatment of Patients with Epilepsy

    One third of patients with epilepsy will continue to have uncontrolled seizures despite treatment with antiseizure medications (ASMs). There is...

    Pavel Klein, Dimitrios Bourikas in Advances in Therapy
    Article Open access 29 May 2024
  4. Consensus on pediatric epilepsy surgery for young children: an investigation by the China Association Against Epilepsy task force on epilepsy surgery

    Researchers have widely acknowledged the therapeutic value of epilepsy surgery for drug-resistant epilepsy. Nonetheless, there is a substantial gap...

    Lixin Cai, Kai Zhang, ... **aoyan Liu in Acta Epileptologica
    Article Open access 14 August 2023
  5. Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

    Background

    There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of...

    Robert Colebunders, Joseph Nelson Siewe Fodjo, ... Sébastien D. Pion in Infectious Diseases of Poverty
    Article Open access 12 January 2024
  6. Structural connectivity as a predictive factor for responsiveness to levetiracetam treatment in epilepsy

    Purpose

    To investigate whether structural connectivity or glymphatic system function is a potential predictive factor for levetiracetam (LEV) response...

    Dong Ah Lee, Ho-Joon Lee, Kang Min Park in Neuroradiology
    Article 28 November 2023
  7. Epilepsy Treatment in Patients with Heart Disease

    Purpose of review

    This review highlights issues pertaining to the treatment of seizures in patients with cardiac disease. These fall into two...

    Article 06 November 2023
  8. The osteoplastic flap for pediatric temporal lobe epilepsy treatment: step-by-step guide and technical nuances

    The osteoplastic flap is an under-utilized craniotomy approach in pediatric temporal lobe epilepsy treatment. By preserving the myofascial attachment...

    Victor M. Lu, John Ragheb, Shelly Wang in Child's Nervous System
    Article 11 November 2023
  9. Robot-assisted treatment of secondary epilepsy caused by parasitic infection: a case report

    Background

    Cerebral sparganosis represents the most severe manifestation of sparganosis, with a relatively low global incidence. For cases of...

    Juan Luo, **n Chen, ... Haifeng Shu in Acta Epileptologica
    Article Open access 15 May 2024
  10. Diagnosis and Treatment of Poststroke Epilepsy: Where Do We Stand?

    Purpose of Review

    Stroke is the most common cause of seizures and epilepsy in older adults. This educational paper aims to give an update on current...

    Matthias Mauritz, Kai-Nicolas Poppert, ... Sebastian Mutzenbach in Current Treatment Options in Neurology
    Article Open access 01 December 2022
  11. Surgical treatment of cavernous malformation-related epilepsy in children: case series, systematic review, and meta-analysis

    Objective : Cerebral cavernous malformations (CCMs) are cerebral vascular lesions that occasionally occur with seizures. We present a retrospective...

    Luca Bosisio, Erica Cognolato, ... Alessandro Consales in Neurosurgical Review
    Article 31 May 2024
  12. Clinical and economic implications of epilepsy management across treatment lines in Spain: a real-life database analysis

    Background

    Epilepsy is a chronic brain disease characterized by recurrent seizures. We investigated real-world management of epilepsy across treatment...

    Rafael Toledano, Vicente Villanueva, ... Paloma Pérez-Domper in Journal of Neurology
    Article Open access 25 August 2023
  13. Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies

    Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may...

    Danielle A. Becker, James W. Wheless, ... Enrique Carrazana in Neurology and Therapy
    Article Open access 21 June 2023
  14. New GABA-Targeting Therapies for the Treatment of Seizures and Epilepsy: II. Treatments in Clinical Development

    The inhibitory neurotransmitter γ-aminobutyric acid (GABA) plays an important role in the modulation of neuronal excitability, and a disruption of...

    Emilio Perucca, H. Steve White, Meir Bialer in CNS Drugs
    Article Open access 21 August 2023
  15. Patient preferences for epilepsy treatment: a systematic review of discrete choice experimental studies

    Background

    This review aimed to 1) identify and assess the quality of discrete choice experiments (DCEs) examining preferences related to epilepsy...

    Sinaa Al-Aqeel, Reem Alotaiwi, Bushra Albugami in Health Economics Review
    Article Open access 18 March 2023
  16. Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes

    Seizures and epilepsy can result from various aetiologies, yet the underlying cause of several epileptic syndromes remains unclear. In that regard,...

    Julia Flammer, Tradite Neziraj, ... Anne-Katrin Pröbstel in Drugs
    Article Open access 25 January 2023
  17. Practical Questions About Rescue Medications for Acute Treatment of Seizure Clusters in Children and Adolescents with Epilepsy in the USA: Expanding Treatment Options to Address Unmet Needs

    Epilepsy is a common pediatric neurological condition, affecting approximately 470,000 children in the USA and having a prevalence of 0.9% in the...

    James W. Wheless, Barry Gidal, ... Enrique Carrazana in Pediatric Drugs
    Article Open access 30 October 2023
  18. Surgical Treatment of Drug-Resistant Generalized Epilepsy

    Purpose of Review

    To summarize current evidence and recent developments in the surgical treatment of drug-resistant generalized epilepsy.

    ...
    Katie L. Bullinger, Abdulrahman Alwaki, Robert E. Gross in Current Neurology and Neuroscience Reports
    Article 17 June 2022
  19. Treatment of Epilepsy in the Setting of Cognitive Decline in Older Adults

    Purpose of Review

    Discuss the state of the literature for the treatment of comorbid epilepsy and cognitive dysfunction, specifically focusing on the...

    Jamie Mayo, Samin Panahi, ... Mary Jo Pugh in Current Treatment Options in Neurology
    Article 19 September 2022
  20. Treatment Outcomes of Newly Diagnosed Epilepsy: A Systematic Review and Meta-analysis

    Background and Objectives

    Understanding the multi-faceted treatment outcomes of newly diagnosed epilepsy is critical for develo** rational...

    Mubeen Janmohamed, Haris Hakeem, ... Patrick Kwan in CNS Drugs
    Article 21 December 2022
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