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Showing 1-20 of 94 results

  1. The feasibility of [18F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study

    Rationale

    Evaluation of the feasibility of [ 18 F]EF5-PET/CT scan in identifying hypoxic lesions in ovarian tumors in prospective clinical setting.

    ...
    Maren Laasik, Johanna Hynninen, ... Sakari Hietanen in EJNMMI Research
    Article Open access 10 September 2020

  2. Detection of metabolic adaptation in a triple-negative breast cancer animal model with [18F]choline-PET imaging as a surrogate for drug resistance

    Purpose

    Test the feasibility of an image-based method to identify taxane resistance in mouse bearing triple-negative breast cancer (TNBC) tumor...

    Andres A. Kohan, Mathieu Lupien, ... Patrick Veit-Haibach in European Journal of Nuclear Medicine and Molecular Imaging
    Article 14 December 2023

  3. The use of PET/MRI in radiotherapy

    Positron emission tomography/magnetic resonance imaging (PET/MRI) is a hybrid imaging technique that quantitatively combines the metabolic and...

    Qi Yan, **a Yan, ... Jianbo Song in Insights into Imaging
    Article Open access 27 February 2024

  4. Repeatability of tumour hypoxia imaging using [18F]EF5 PET/CT in head and neck cancer

    Purpose

    Hypoxia contributes to radiotherapy resistance and more aggressive behaviour of several types of cancer. This study was designed to evaluate...

    Antti Silvoniemi, Sami Suilamo, ... Heikki Minn in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 26 October 2017

  5. Highlight selection of radiochemistry and radiopharmacy developments by editorial board

    Background

    The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biannual highlight commentary to update the readership on trends in...

    Jun Toyohara, Mohammed Al-Qahtani, ... Emerson Bernardes in EJNMMI Radiopharmacy and Chemistry
    Article Open access 01 October 2022

  6. Investigation of atovaquone-induced spatial changes in tumour hypoxia assessed by hypoxia PET/CT in non-small cell lung cancer patients

    Background

    Tumour hypoxia promotes an aggressive tumour phenotype and enhances resistance to anticancer treatments. Following the recent observation...

    Pauline Bourigault, Michael Skwarski, ... Daniel R. McGowan in EJNMMI Research
    Article Open access 29 December 2021

  7. Radionuclide imaging and therapy directed towards the tumor microenvironment: a multi-cancer approach for personalized medicine

    Targeted radionuclide theranostics is becoming more and more prominent in clinical oncology. Currently, most nuclear medicine compounds researched...

    Circe D. van der Heide, Simone U. Dalm in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 05 July 2022

  8. Hypoxia PET imaging beyond 18F-FMISO in patients with high-grade glioma: 18F-FAZA and other hypoxia radiotracers

    Purpose

    High-grade gliomas are aggressive primitive brain tumors presenting aberrant vasculature, regional necrosis, and areas of hypoxia. Tumor...

    Natale Quartuccio, Riccardo Laudicella, ... Maria Picchio in Clinical and Translational Imaging
    Article 06 February 2020

  9. Comparison of FDG and FMISO uptakes and distributions in head and neck squamous cell cancer tumors

    Purpose

    Glycolysis is increased by hypoxia, suggesting a possible correlation between the accumulation of 2-[18F]fluoro-2-deoxy-D-glucose (FDG) in...

    Sadek A. Nehmeh, Mohamed B. Moussa, ... Heiko Schöder in EJNMMI Research
    Article Open access 14 April 2021

  11. Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future perspectives

    Dynamic PET (dPET) studies have been used until now primarily within research purposes. Although it is generally accepted that the information...

    Antonia Dimitrakopoulou-Strauss, Leyun Pan, Christos Sachpekidis in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 19 May 2020

  13. Positron Emission Tomography and Molecular Imaging of Head and Neck Malignancies

    Purpose of Review

    Metabolic reprogramming and avid fluorodeoxyglucose (FDG) uptake in locally advanced head and neck squamous cell carcinomas and...

    Farshad Moradi in Current Radiology Reports
    Article 11 September 2020

  14. Therapeutic targeting of the hypoxic tumour microenvironment

    Hypoxia is prevalent in human tumours and contributes to microenvironments that shape cancer evolution and adversely affect therapeutic outcomes....

    Dean C. Singleton, Andrew Macann, William R. Wilson in Nature Reviews Clinical Oncology
    Article 29 July 2021

  15. [18F]FMISO PET/CT as a preoperative prognostic factor in patients with pancreatic cancer

    Background

    While [ 18 F]fluoromisonidazole (FMISO), a representative PET tracer to detect hypoxia, is reported to be able to prospect the prognosis...

    Tomohiko Yamane, Masayasu Aikawa, ... Ichiei Kuji in EJNMMI Research
    Article Open access 09 May 2019

  16. Longitudinal PET imaging of tumor hypoxia during the course of radiotherapy

    Hypoxia results from an imbalance between oxygen supply and consumption. It is a common phenomenon in solid malignant tumors such as head and neck...

    Sonja Stieb, Afroditi Eleftheriou, ... Oliver Riesterer in European Journal of Nuclear Medicine and Molecular Imaging
    Article 20 August 2018

  17. Highlights of the 30th Annual Congress of the EANM, Vienna 2017: “Yes we can – make nuclear medicine great again”

    The 30th Annual Congress of the European Association of Nuclear Medicine (EANM) was held in Vienna, Austria, from 21 to 25 October 2017 under the...

    Stefano Fanti, Rachele Bonfiglioli, Clemens Decristoforo in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 03 May 2018

  19. PET Imaging of Cardiac Hypoxia: Hitting Hypoxia Where It Hurts

    Purpose of Review

    In this review, we outline the potential for hypoxia imaging as a diagnostic and prognostic tool in cardiology. We describe the lead...

    Victoria R. Pell, Friedrich Baark, ... Richard Southworth in Current Cardiovascular Imaging Reports
    Article Open access 23 February 2018

  20. Molecular mechanisms of hypoxia in cancer

    Purpose

    Hypoxia is a condition of insufficient oxygen to support metabolism which occurs when the vascular supply is interrupted, or when a tumour...

    Amarnath Challapalli, Laurence Carroll, Eric O. Aboagye in Clinical and Translational Imaging
    Article Open access 11 May 2017
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