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Clinical, radiological and electrophysiological predictors for drug-resistant epilepsy
BackgroundEpilepsy is the third chronic brain illness worldwide. About a third of the epileptic patients will be drug resistant. Early identification...
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Breath-Hold-Triggered BOLD fMRI in Drug-Resistant Nonlesional Focal Epilepsy—A Pilot Study
PurposeIndividuals with drug-resistant epilepsy may benefit from epilepsy surgery. In nonlesional cases, where no epileptogenic lesion can be...
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Utility of genetic testing in the pre-surgical evaluation of children with drug-resistant epilepsy
We evaluated the utility of genetic testing in the pre-surgical evaluation of pediatric patients with drug-resistant focal epilepsy. This...
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Arterial spin labeling perfusion MRI applications in drug-resistant epilepsy and epileptic emergency
Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide. Drug-resistant epilepsy (DRE), status...
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The role of neuromodulation in the management of drug-resistant epilepsy
Drug-resistant epilepsy (DRE) poses significant challenges in terms of effective management and seizure control. Neuromodulation techniques have...
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Disparities in pediatric drug-resistant epilepsy care
IntroductionEpilepsy affects millions of children worldwide, with 20–40% experiencing drug-resistant epilepsy (DRE) who are recommended for epilepsy...
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The impact of referring patients with drug-resistant focal epilepsy to an epilepsy center for presurgical diagnosis
BackgroundEpilepsy surgery is an established treatment for drug-resistant focal epilepsy (DRFE) that results in seizure freedom in about 60% of...
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Etiological analysis of 167 cases of drug-resistant epilepsy in children
BackgroundTo analyze the etiological distribution characteristics of drug-resistant epilepsy (DRE) in children, with the aim of providing valuable...
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Prevalence and risk factors associated with drug-resistant epilepsy in adult epileptic patients
BackgroundDespite the plethora of pharmacotherapy and acquisition of new AEDs, there is a hard core of patients who persistently fail to respond to...
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Efficacy and safety of modified medium-chain triglyceride ketogenic diet in patients with drug-resistant epilepsy
BackgroundMedium-chain triglyceride ketogenic diet (MCTKD) is previously less commonly used in China. This study was aimed to assess the efficacy...
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Surgical Treatment of Drug-Resistant Generalized Epilepsy
Purpose of ReviewTo summarize current evidence and recent developments in the surgical treatment of drug-resistant generalized epilepsy.
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Drug resistant epilepsy and associated factors among children with epilepsies in Tanzania: a cross-sectional study
BackgroundEpilepsy contributes to high morbidity among children and adolescents in develo** countries. A quarter of all children with epilepsy will...
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Current Principles in the Management of Drug-Resistant Epilepsy
Drug-resistant epilepsy is associated with poor health outcomes and increased economic burden. In the last three decades, various new antiseizure...
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MR-guided laser interstitial thermal therapy for drug-resistant lesional epilepsy: a single-center experience
BackgroundTo describe and report the efficacy and safety of MR-guided laser interstitial thermal therapy (MRgLITT) in the treatment of drug-resistant...
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Frame-based versus robot-assisted stereo-electro-encephalography for drug-resistant epilepsy
BackgroundStereoelectroencephalography (SEEG) is an effective presurgical invasive evaluation for drug-resistant epilepsies. The introduction of...
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Neuronal autoantibodies in a sample of Egyptian patients with drug-resistant epilepsy
BackgroundEpilepsy is one of the most common and chronic neurological diseases. About one-third of epilepsy patients do not achieve seizure freedom...
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Emerging personalized virtual brain models: next-generation resection neurosurgery for drug-resistant epilepsy?
Recently, a novel workflow known as the virtual epileptic patient (VEP) has been proposed by a research team from Aix Marseille Université in their...
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Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy
BackgroundA prior small-scale single center study suggested an association between celiac disease (CD)-type immunity and refractory temporal lobe...
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Real-world evidence of epidemiology, patient characteristics, and mortality in people with drug-resistant epilepsy in the United Kingdom, 2011–2021
BackgroundA third of people with epilepsy are drug resistant. People with drug-resistant epilepsy (DRE) have a higher risk of mortality and physical...
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Long-term follow-up of vagus nerve stimulation in drug-resistant KCNT1-related epilepsy: a case presentation
BackgroundThe KCNT1 gene encodes a Na + -activated K + channel. Gain-of-function mutations of KCNT1 lead to autosomal dominant sleep-related hypermotor...