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Showing 1-20 of 5,276 results
  1. Clinical, radiological and electrophysiological predictors for drug-resistant epilepsy

    Background

    Epilepsy is the third chronic brain illness worldwide. About a third of the epileptic patients will be drug resistant. Early identification...

    Noha T. Abokrysha, Noha Taha, ... Ghada Hatem in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
    Article Open access 29 March 2023
  2. Breath-Hold-Triggered BOLD fMRI in Drug-Resistant Nonlesional Focal Epilepsy—A Pilot Study

    Purpose

    Individuals with drug-resistant epilepsy may benefit from epilepsy surgery. In nonlesional cases, where no epileptogenic lesion can be...

    Christian M. Boßelmann, Josua Kegele, ... Till-Karsten Hauser in Clinical Neuroradiology
    Article Open access 11 December 2023
  3. Utility of genetic testing in the pre-surgical evaluation of children with drug-resistant epilepsy

    We evaluated the utility of genetic testing in the pre-surgical evaluation of pediatric patients with drug-resistant focal epilepsy. This...

    Sarah Alsubhi, Saoussen Berrahmoune, ... Kenneth A. Myers in Journal of Neurology
    Article 23 January 2024
  4. Arterial spin labeling perfusion MRI applications in drug-resistant epilepsy and epileptic emergency

    Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide. Drug-resistant epilepsy (DRE), status...

    Yingchun Xu, Ge Tan, ... Ling Liu in Acta Epileptologica
    Article Open access 28 September 2023
  5. The role of neuromodulation in the management of drug-resistant epilepsy

    Drug-resistant epilepsy (DRE) poses significant challenges in terms of effective management and seizure control. Neuromodulation techniques have...

    HusamEddin Salama, Ahmed Salama, ... Nir Shimony in Neurological Sciences
    Article 20 April 2024
  6. Disparities in pediatric drug-resistant epilepsy care

    Introduction

    Epilepsy affects millions of children worldwide, with 20–40% experiencing drug-resistant epilepsy (DRE) who are recommended for epilepsy...

    Melissa A. LoPresti, Lu Zhang, Sandi Lam in Child's Nervous System
    Article Open access 17 February 2023
  7. The impact of referring patients with drug-resistant focal epilepsy to an epilepsy center for presurgical diagnosis

    Background

    Epilepsy surgery is an established treatment for drug-resistant focal epilepsy (DRFE) that results in seizure freedom in about 60% of...

    Leonhard Mann, Felix Rosenow, ... Catrin Mann in Neurological Research and Practice
    Article Open access 14 December 2023
  8. Etiological analysis of 167 cases of drug-resistant epilepsy in children

    Background

    To analyze the etiological distribution characteristics of drug-resistant epilepsy (DRE) in children, with the aim of providing valuable...

    Ran-Ran Zuo, Mei **, Su-Zhen Sun in Italian Journal of Pediatrics
    Article Open access 13 March 2024
  9. Prevalence and risk factors associated with drug-resistant epilepsy in adult epileptic patients

    Background

    Despite the plethora of pharmacotherapy and acquisition of new AEDs, there is a hard core of patients who persistently fail to respond to...

    Hazem Marouf, Lobna A. Mohamed, ... Dina Elsayed Gaber in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
    Article Open access 15 November 2023
  10. Efficacy and safety of modified medium-chain triglyceride ketogenic diet in patients with drug-resistant epilepsy

    Background

    Medium-chain triglyceride ketogenic diet (MCTKD) is  previously less commonly used in China. This study was aimed to assess the efficacy...

    Hua Li, Yao Wang, ... Liming Zhao in Acta Epileptologica
    Article Open access 06 March 2024
  11. Surgical Treatment of Drug-Resistant Generalized Epilepsy

    Purpose of Review

    To summarize current evidence and recent developments in the surgical treatment of drug-resistant generalized epilepsy.

    ...
    Katie L. Bullinger, Abdulrahman Alwaki, Robert E. Gross in Current Neurology and Neuroscience Reports
    Article 17 June 2022
  12. Drug resistant epilepsy and associated factors among children with epilepsies in Tanzania: a cross-sectional study

    Background

    Epilepsy contributes to high morbidity among children and adolescents in develo** countries. A quarter of all children with epilepsy will...

    Obrey H Urio, Edward Kija, ... Helga Naburi in BMC Neurology
    Article Open access 02 January 2024
  13. Current Principles in the Management of Drug-Resistant Epilepsy

    Drug-resistant epilepsy is associated with poor health outcomes and increased economic burden. In the last three decades, various new antiseizure...

    Nathan A. Shlobin, Josemir W. Sander in CNS Drugs
    Article 20 May 2022
  14. MR-guided laser interstitial thermal therapy for drug-resistant lesional epilepsy: a single-center experience

    Background

    To describe and report the efficacy and safety of MR-guided laser interstitial thermal therapy (MRgLITT) in the treatment of drug-resistant...

    Hongchuan Niu, Kai Li, ... Changyu Lu in Chinese Neurosurgical Journal
    Article Open access 18 September 2023
  15. Frame-based versus robot-assisted stereo-electro-encephalography for drug-resistant epilepsy

    Background

    Stereoelectroencephalography (SEEG) is an effective presurgical invasive evaluation for drug-resistant epilepsies. The introduction of...

    Chang-Lin Han, Chien-Chen Chou, ... Cheng-Chia Lee in Acta Neurochirurgica
    Article 16 February 2024
  16. Neuronal autoantibodies in a sample of Egyptian patients with drug-resistant epilepsy

    Background

    Epilepsy is one of the most common and chronic neurological diseases. About one-third of epilepsy patients do not achieve seizure freedom...

    Hadeer Mohamed, Mahmoud Hemeda, ... Mona Wahid El Din in The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
    Article Open access 22 June 2023
  17. Emerging personalized virtual brain models: next-generation resection neurosurgery for drug-resistant epilepsy?

    Recently, a novel workflow known as the virtual epileptic patient (VEP) has been proposed by a research team from Aix Marseille Université in their...

    Qiao Wang, Guangyuan **, ... Liankun Ren in Acta Epileptologica
    Article Open access 07 July 2023
  18. Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy

    Background

    A prior small-scale single center study suggested an association between celiac disease (CD)-type immunity and refractory temporal lobe...

    Maria Peltola, Katri Kaukinen, ... Jukka Peltola in Journal of Neurology
    Article Open access 10 February 2024
  19. Real-world evidence of epidemiology, patient characteristics, and mortality in people with drug-resistant epilepsy in the United Kingdom, 2011–2021

    Background

    A third of people with epilepsy are drug resistant. People with drug-resistant epilepsy (DRE) have a higher risk of mortality and physical...

    Rohit Shankar, **aocong Li Marston, ... Lara Groves in Journal of Neurology
    Article Open access 19 January 2024
  20. Long-term follow-up of vagus nerve stimulation in drug-resistant KCNT1-related epilepsy: a case presentation

    Background

    The KCNT1 gene encodes a Na + -activated K + channel. Gain-of-function mutations of KCNT1 lead to autosomal dominant sleep-related hypermotor...

    Meng Wang, Guifu Geng, ... Jianguo Shi in Acta Epileptologica
    Article Open access 20 November 2022
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