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1. MIB Guides: Preclinical Radiopharmaceutical Dosimetry

   Preclinical dosimetry is essential for guiding the design of animal radiopharmaceutical biodistribution, imaging, and therapy experiments, evaluating...

   Lukas M. Carter, Pat B. Zanzonico in Molecular Imaging and Biology

   Article 14 November 2023
   

2. Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review

   Purpose

   ¹⁷⁷ Lu- labelled somatostatin analog DOTATATE is an excellent vector for systemic radiation therapy in NETs. However, this treatment can...

   Amit Nautiyal, Sofia Michopoulou, Matt Guy in Clinical and Translational Imaging

   Article 20 September 2023
   

3. EANM enabling guide: how to improve the accessibility of clinical dosimetry

   Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic...

   Jonathan Gear, Caroline Stokke, ... Pablo Minguez Gabiña in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 22 April 2023

4. EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials

   The numbers of diagnostic and therapeutic nuclear medicine agents under investigation are rapidly increasing. Both novel emitters and novel carrier...

   Caroline Stokke, Silvano Gnesin, ... Jonathan Gear in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 17 February 2024
   

5. 90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework

   Purpose

   90Y SPECT-based dosimetry following radioembolization (RE) in liver malignancies is challenging due to the inherent scatter and the poor...

   Yixuan Jia, Zongyu Li, ... Yuni K. Dewaraja in EJNMMI Physics

   Article Open access 13 December 2023
   

6. Uncertainty Analysis of Time-Integrated Activity Coefficient in Single-Time-Point Dosimetry Using Bayesian Fitting Method

   Purpose

   Calculation of the uncertainty of the individual time-integrated activity coefficient (TIACs) is desirable in molecular radiotherapy. However,...

   Achmad Faturrahman Jundi, M. Dlorifun Naqiyyun, ... Deni Hardiansyah in Nuclear Medicine and Molecular Imaging

   Article 23 February 2024
   

7. Dosimetry and pharmacokinetics of [¹⁷⁷Lu]Lu-satoreotide tetraxetan in patients with progressive neuroendocrine tumours

   Purpose

   To evaluate the dosimetry and pharmacokinetics of the novel radiolabelled somatostatin receptor antagonist [ ¹⁷⁷ Lu]Lu-satoreotide tetraxetan...

   Seval Beykan Schürrle, Uta Eberlein, ... Michael Lassmann in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 26 March 2024
   

8. DosePatch: physics-inspired crop** layout for patch-based Monte Carlo simulations to provide fast and accurate internal dosimetry

   Background

   Dosimetry-based personalized therapy was shown to have clinical benefits e.g. in liver selective internal radiation therapy (SIRT). Yet,...

   Francesca De Benetti, Julia Brosch-Lenz, ... Thomas Wendler in EJNMMI Physics

   Article Open access 26 June 2024
   

9. Trans-arterial Radioembolization Dosimetry in 2022

   Trans-arterial radioembolization is currently performed using ⁹⁰ Y-loaded glass or resin microspheres and also using ¹⁶⁶ Ho-loaded microspheres. The...

   Etienne Garin, Boris Guiu, ... Xavier Palard in CardioVascular and Interventional Radiology

   Article 18 August 2022
   

10. Internal dosimetry study of [⁸²Rb]Cl using a long axial field-of-view PET/CT

    Purpose

    Long axial field-of-view (LAFOV) positron emission tomography (PET) systems allow to image all major organs with one bed position, which is...

    Lorenzo Mercolli, Carola Bregenzer, ... Federico Caobelli in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 26 February 2024
    

11. EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor- and PSMA-targeting ligands

    The purpose of the EANM Dosimetry Committee is to provide recommendations and guidance to scientists and clinicians on patient-specific dosimetry....

    Katarina Sjögreen Gleisner, Nicolas Chouin, ... Jonathan Gear in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 14 March 2022
    

12. Automatic healthy liver segmentation for holmium-166 radioembolization dosimetry

    Background

    For safe and effective holmium-166 ( ¹⁶⁶ Ho) liver radioembolization, dosimetry is crucial and requires accurate healthy liver definition....

    Martina Stella, Rob van Rooij, ... Arthur J. A. T. Braat in EJNMMI Research

    Article Open access 15 July 2023
    

13. Optimization of the radiation dosimetry protocol in Lutetium-177-PSMA therapy: toward clinical implementation

    Background

    Dosimetry in [ ¹⁷⁷ Lu]Lu-PSMA therapy is a valuable tool to assess treatment efficacy and toxicity. This study aims to develop a clinically...

    Steffie M. B. Peters, Maaike C. T. Mink, ... Mark W. Konijnenberg in EJNMMI Research

    Article Open access 24 January 2023
    

14. Bone marrow dosimetry in low volume mHSPC patients receiving Lu-177-PSMA therapy using SPECT/CT

    Background

    Bone marrow toxicity in advanced prostate cancer patients who receive [ ¹⁷⁷ Lu]Lu-PSMA-617 is a well-known concern. In early stage patients;...

    Dagmar Grob, Bastiaan M. Privé, ... Steffie M. B. Peters in EJNMMI Physics

    Article Open access 03 April 2024
    

15. ⁹⁰Y post-radioembolization clinical assessment with whole-body Biograph Vision Quadra PET/CT: image quality, tumor, liver and lung dosimetry

    Purpose

    Evaluation of ⁹⁰ Y liver radioembolization post-treatment clinical data using a whole-body Biograph Vision Quadra PET/CT to investigate the...

    Konstantinos G. Zeimpekis, Lorenzo Mercolli, ... Hendrik Rathke in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 13 February 2024
    

16. Use of imaging-based dosimetry for personalising radiopharmaceutical therapy of cancer

    Theranostics – i.e., the combination of molecular imaging and radiopharmaceutical therapy of cancer targeting a common biological feature – is a...

    Jean-Mathieu Beauregard in Cancer Imaging

    Article Open access 09 December 2022

17. Considerations on dosimetry for in vitro assessment of e-cigarette toxicity

    Electronic cigarettes (or e-cigarettes) can be used as smoking cessation aid. Some studies tend to show that they are less hazardous than tobacco...

    Valérie Forest, Clément Mercier, Jérémie Pourchez in Respiratory Research

    Article Open access 17 December 2022
    

18. Quantitative calibration of Tb-161 SPECT/CT in view of personalised dosimetry assessment studies

    Background

    Terbium-161 ( ¹⁶¹ Tb)-based radionuclide therapy poses an alternative to current Lutetium-177 ( ¹⁷⁷ Lu) approaches with the additional benefit...

    Lachlan McIntosh, Price Jackson, ... Michael S. Hofman in EJNMMI Physics

    Article Open access 19 February 2024
    

19. Normal organ dosimetry for thyroid cancer patients treated with radioiodine as part of the multi-centre multi-national Horizon 2020 MEDIRAD project

    Purpose

    Dosimetry is rarely performed for the treatment of differentiated thyroid cancer patients with Na[ ¹³¹ I]I (radioiodine), and information...

    Jan Taprogge, Alex Vergara-Gil, ... Glenn Flux in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 10 June 2023
    

20. From bench to bedside: ⁶⁴Cu/¹⁷⁷Lu 1C1m-Fc anti TEM-1: mice-to-human dosimetry extrapolations for future theranostic applications

    The development of diagnostic and therapeutic radiopharmaceuticals is an hot topic in nuclear medicine. Several radiolabeled antibodies are under...

    Silvano Gnesin, Nicolas Chouin, ... Judith Anna Delage in EJNMMI Research

    Article Open access 14 June 2023