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Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review
Purpose177 Lu- labelled somatostatin analog DOTATATE is an excellent vector for systemic radiation therapy in NETs. However, this treatment can...
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EANM guidance document: dosimetry for first-in-human studies and early phase clinical trials
The numbers of diagnostic and therapeutic nuclear medicine agents under investigation are rapidly increasing. Both novel emitters and novel carrier...
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Trans-arterial Radioembolization Dosimetry in 2022
Trans-arterial radioembolization is currently performed using 90 Y-loaded glass or resin microspheres and also using 166 Ho-loaded microspheres. The...
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EANM dosimetry committee recommendations for dosimetry of 177Lu-labelled somatostatin-receptor- and PSMA-targeting ligands
The purpose of the EANM Dosimetry Committee is to provide recommendations and guidance to scientists and clinicians on patient-specific dosimetry....
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Use of imaging-based dosimetry for personalising radiopharmaceutical therapy of cancer
Theranostics – i.e., the combination of molecular imaging and radiopharmaceutical therapy of cancer targeting a common biological feature – is a...
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Radiosynthesis automation, non-human primate biodistribution and dosimetry of K+ channel tracer [11C]3MeO4AP
Background4-Aminopyridine (4AP) is a medication for the symptomatic treatment of multiple sclerosis. Several 4AP-based PET tracers have been...
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Considerations on dosimetry for in vitro assessment of e-cigarette toxicity
Electronic cigarettes (or e-cigarettes) can be used as smoking cessation aid. Some studies tend to show that they are less hazardous than tobacco...
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Predictive value of 99mTc-MAA-based dosimetry in personalized 90Y-SIRT planning for liver malignancies
BackgroundSelective internal radiation therapy with 90 Y radioembolization aims to selectively irradiate liver tumours by administering radioactive...
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Accuracy of patient-specific I-131 dosimetry using hybrid whole-body planar-SPECT/CT I-123 and I-131 imaging
PurposeThis study aimed to assess the accuracy of patient-specific absorbed dose calculations for tumours and organs at risk in radiopharmaceutical...
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Impact of scatter correction on personalized dosimetry in selective internal radiotherapy using 166Ho-PLLA: a single-center study including Monte-Carlo simulation, phantom and patient imaging
BackgroundDevelopments in transarterial radioembolization led to the conception of new microspheres loaded with holmium-166 ( 166 Ho). However, due to...
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The role of biomarkers and dosimetry parameters in overall and progression free survival prediction for patients treated with personalized 90Y glass microspheres SIRT: a preliminary machine learning study
BackgroundOverall Survival (OS) and Progression-Free Survival (PFS) analyses are crucial metrics for evaluating the efficacy and impact of treatment....
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Development, Characterization, and Radiation Dosimetry Studies of 18F-BMS-986229, a 18F-Labeled PD-L1 Macrocyclic Peptide PET Tracer
PurposeIn cancer immunotherapy, the blockade of the interaction between programmed death-1 and its ligand (PD-1:PD-L1) has proven to be one of the...
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Human biodistribution and radiation dosimetry for the tau tracer [18F]Florzolotau in healthy subjects
BackgroundTau pathology plays a crucial role in neurodegeneration diseases including Alzheimer’s disease (AD) and non-AD diseases such as progressive...
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Voxel-Based Internal Dosimetry for 177Lu-Labeled Radiopharmaceutical Therapy Using Deep Residual Learning
PurposeIn this study, we propose a deep learning (DL)–based voxel-based dosimetry method in which dose maps acquired using the multiple voxel S-value...
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Dosimetry and efficacy of a tau PET tracer [18F]MK-6240 in Japanese healthy elderly and patients with Alzheimer’s disease
ObjectiveA new tau PET tracer [ 18 F]MK-6240 has been developed; however, its dosimetry and pharmacokinetics have been published only for a European...
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Characteristics of a real-time radiation exposure dosimetry system using a synthetic ruby for radiotherapy
Radiotherapy-related medical accidents are frequently caused by planning problems, excessive irradiation during radiotherapy, or patient movement....
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Small-field dosimetry with detector-specific output correction factor for single-isocenter stereotactic radiotherapy of single and multiple brain metastases
Recently, the International Atomic Energy Agency and the American Association of Physicists in Medicine reported correction factors (CFs) for...
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Characterization of ferrous-agarose-xylenol gel dosimeter at 60Co γ-rays beam therapy unit
Fricke gel dosimetry is a valuable technique used for recording 3D dose distribution in radiotherapy. Herein, we present the dosimetric...
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Diagnostic and Dosimetry Features of [64Cu]CuCl2 in High-Grade Paediatric Infiltrative Gliomas
Purpose of the ReportPaediatric diffuse high-grade gliomas (PDHGG) are rare central nervous system neoplasms lacking effective therapeutic options....
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EANM dosimetry committee series on standard operational procedures: a unified methodology for 99mTc-MAA pre- and 90Y peri-therapy dosimetry in liver radioembolization with 90Y microspheres
The aim of this standard operational procedure is to standardize the methodology employed for the evaluation of pre- and post-treatment absorbed dose...
