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Nanocrystals: an emerging paradigm for cancer therapeutics
BackgroundMedical fraternity are continuously pitching toward the development of novel mechanisms to combat the menace of cancer and to enhance the...
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Immunotherapy: The Fourth Domain in Oral Cancer Therapeutics
Owing to high global prevalence, incidence and associated mortality, cancer of head and neck particularly oral cancer remains a cardinal domain for...
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Development of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities
Immunotherapy represented by anti-PD-(L)1 and anti-CTLA-4 inhibitors has revolutionized cancer treatment, but challenges related to resistance and...
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Immune checkpoint targeting antibodies hold promise for combinatorial cancer therapeutics
Through improving the immune system's ability to recognize and combat tumor cells as well as its receptivity to changes in the tumor...
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Pediatric Cancer Therapeutics Development
This book provides a comprehensive overview of the scientific, medical, regulatory, and economic considerations associated with the discovery,...
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Psoriasis in the Era of Targeted Cancer Therapeutics: A Systematic Review on De Novo and Pre-existing Psoriasis in Oncologic Patients Treated with Emerging Anti-neoplastic Agents
New advancements in medicine have paved the way for targeted therapies and immune checkpoint inhibitors (ICIs), which have become mainstays of cancer...
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Targeting crosstalk of signaling pathways in cancer stem cells: a promising approach for development of novel anti-cancer therapeutics
Wnt, Hedgehog (Hh), and Notch signaling pathways are the evolutionarily conserved signaling pathways that regulate the embryonic development and also...
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Fundamental concepts of protein therapeutics and spacing in oncology: an updated comprehensive review
Current treatment regimens in cancer cases cause significant side effects and cannot effectively eradicate the advanced disease. Hence, much effort...
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Real-World Evidence Studies in Oncology Therapeutics: Hope or Hype?
Randomized controlled trial (RCT) remains a gold standard in evidence-based medicine for assessing the efficacy and safety of cancer therapies....
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Nucleic acid therapeutics as differentiation agents for myeloid leukemias
Differentiation therapy has proven to be a success story for patients with acute promyelocytic leukemia. However, the remaining subtypes of acute...
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Novel Cancer Therapeutics and Implications for Rehabilitation
Purpose of ReviewTo determine how the more recently developed cancer treatments may impact patient function. To determine how rehabilitation medicine...
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Two-dimensional speckle tracking echocardiography help identify breast cancer therapeutics–related cardiac dysfunction
BackgroundCancer therapeutics–related cardiac dysfunction (CTRCD) from different chemotherapy strategies are underdetermined by echocardiography. As...
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The recent update and advancements of natural products in targeting the Wnt/β-Catenin pathway for cancer prevention and therapeutics
The Wnt/β-Catenin pathway (Wnt/β-CatP) is implicated in accelerating carcinogenesis and cancer progression, contributing to increased morbidity and...
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Non-cancer to anti-cancer: investigation of human ether-a-go-go-related gene potassium channel inhibitors as potential therapeutics
BackgroundThe expression of hERG K + channels is observed in various cancer cells including epithelial, neuronal, leukemic, and connective tissue....
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Recent advances and future perspectives in the therapeutics of prostate cancer
Prostate cancer (PC) is one of the most common cancers in males and the fifth leading reason of death. Age, ethnicity, family history, and genetic...
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Skin cancer therapeutics: nano-drug delivery vectors—present and beyond
BackgroundSkin cancers are among the widely prevalent forms of cancer worldwide. The increasing industrialization and accompanied environmental...
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Alpha Particle–Emitting Radiopharmaceuticals as Cancer Therapy: Biological Basis, Current Status, and Future Outlook for Therapeutics Discovery
Critical advances in radionuclide therapy have led to encouraging new options for cancer treatment through the pairing of clinically useful...
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Anti-angiogenesis in cancer therapeutics: the magic bullet
BackgroundAngiogenesis is the formation of new vascular networks from preexisting ones through the migration and proliferation of differentiated...
