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Brain tumor related epilepsy: pathophysiological approaches and rational management of antiseizure medication
BackgroundBrain tumor related epilepsy (BTRE) is a common complication of cerebral tumors and its incidence is highly dependent on the type of tumor,...
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Low-grade glioma of the temporal lobe and tumor-related epilepsy in children
PurposeLow-grade glioma is the most common brain tumor among children and adolescents. When these tumors arise in the temporal lobe, patients...
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Lacosamide in monotherapy in BTRE (brain tumor-related epilepsy): results from an Italian multicenter retrospective study
PurposeLacosamide (LCM) is a third-generation anti-seizure medication (ASM) approved for focal onset epilepsy in patients agedââ„â4.378 Previous...
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Identification of a common brain network associated with lesional epilepsy
Stroke is the leading cause of neurological diseases globally. Remarkably, epilepsy is a common complication of stroke, which greatly impairs the...
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Relevant pharmacologic interactions in the concurrent management of brain tumor-related epilepsy and venous thromboembolism: a systematic review
IntroductionCo-administration of direct oral anticoagulants (DOACs) with antiepileptic drugs (AEDs) is increasingly common in brain tumor patients....
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Clinical characteristics of brain tumor-related epilepsy and factors influencing the identification of epilepsy-associated tumors
BackgroundTo analyze the clinical features of brain tumor-related epilepsy (BTRE) and explore the factors influencing the identification of...
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A multicenter, matched caseâcontrol analysis comparing burden of illness among patients with tuberous sclerosis complex related epilepsy, generalized idiopathic epilepsy, and focal epilepsy in Germany
BackgroundDepending on the underlying etiology and epilepsy type, the burden of disease for patients with seizures can vary significantly. This...
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Brain Tumors A Pocket Guide
This concise book serves as a practical primer for the care of patients with primary brain tumors.
Divided into two major sections, the first provides...
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Tumor-associated epilepsy in patients with brain metastases: necrosis-to-tumor ratio forecasts postoperative seizure freedom
Surgical resection is highly effective in the treatment of tumor-related epilepsy (TRE) in patients with brain metastases (BM). Nevertheless, some...
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Efficacy of clobazam as add-on therapy in brain tumor-related epilepsy
PurposeBrain tumor-related epilepsy (TRE) is often resistant to currently available antiepileptic medications (AEDs). Clobazam was initially approved...
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Biomolecular mechanisms of epileptic seizures and epilepsy: a review
Epilepsy is a recurring neurological disease caused by the abnormal electrical activity in the brain. This disease has caused about 50 new cases in...
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Evaluating the glymphatic system via magnetic resonance diffusion tensor imaging along the perivascular spaces in brain tumor patients
PurposeTo investigate glymphatic system function in patients with brain tumors, including both primary and secondary tumors, using diffusion tensor...
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Narrative Review of Brivaracetam: Preclinical Profile and Clinical Benefits in the Treatment of Patients with Epilepsy
One third of patients with epilepsy will continue to have uncontrolled seizures despite treatment with antiseizure medications (ASMs). There is...
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Simultaneous high-resolution whole-brain MR spectroscopy and [18F]FDG PET for temporal lobe epilepsy
PurposePrecise lateralizing the epileptogenic zone in patients with drug-resistant mesial temporal lobe epilepsy (mTLE) remains challenging,...
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Are anti-glutamic acid decarboxylase 65-kDa isoform antibodies related to diabetes or brain tumor?
BackgroundAntibodies against the 65-kDa isoform of glutamic acid decarboxylase (GAD65) are biomarkers of autoimmune disorders and are more common in...
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Seizure Management and Prophylaxis Considerations in Patients with Brain Tumors
Purpose of ReviewThe article gives an overview of the current knowledge in the management of tumor related epilepsy, including systematic reviews and...
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Effectiveness and tolerability of brivaracetam in patients with epilepsy stratified by comorbidities and etiology in the real world: 12-month subgroup data from the international EXPERIENCE pooled analysis
ObjectiveTo assess the effectiveness and tolerability of brivaracetam (BRV) in adults with epilepsy by specific comorbidities and epilepsy etiologies.
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Utility of genetic testing in the pre-surgical evaluation of children with drug-resistant epilepsy
We evaluated the utility of genetic testing in the pre-surgical evaluation of pediatric patients with drug-resistant focal epilepsy. This...
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A new approach for clinical translation of infrared spectroscopy: exploitation of the signature of glioblastoma for general brain tumor recognition
PurposeInfrared (IR) spectroscopy has the potential for tumor delineation in neurosurgery. Previous research showed that IR spectra of brain tumors...
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Quantitative measurement of peritumoral concentrations of glutamate, N-acetyl aspartate, and lactate on magnetic resonance spectroscopy predicts glioblastoma-related refractory epilepsy
BackgroundIncreased extracellular glutamate is known to cause epileptic seizures in patients with glioblastoma (GBM). However, predicting whether the...