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Inflammation in aortic surgery: postoperative evolution of biomarkers according pathologies and segments of the aorta
ObjectivesAortic pathologies often present with elevated inflammatory biomarkers due to the nature of the disease. Open aortic surgery causes...
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Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention
Aortic blood flow patterns are closely linked to the morphology and function of the left ventricle, aortic valve and aorta. These flow patterns...
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False lumen hemodynamics and partial thrombosis in chronic aortic dissection of the descending aorta
ObjectivesPartial thrombosis of the false lumen (FL) in patients with chronic aortic dissection (AD) of the descending aorta has been associated with...
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Histopathology reveals concealed aortic valve inflammation
BackgroundThe extent of aortic valve inflammation in patients undergoing aortic valve replacement (AVR) is unsettled. The significance of aortic...
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SIRT6 is an epigenetic repressor of thoracic aortic aneurysms via inhibiting inflammation and senescence
Thoracic aortic aneurysms (TAAs) develop asymptomatically and are characterized by dilatation of the aorta. This is considered a life-threating...
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Granulomatous inflammation mimicking a hematoma around the replaced ascending aorta in magnetic resonance imaging: a case report
BackgroundGranulomatous inflammation results from various causes including infections and allergic reactions. It can appear as high signal intensity...
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Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice
BackgroundMatrix metalloproteinase 12 (MMP12) is a macrophage-secreted protein that is massively upregulated as a pro-inflammatory factor in...
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Descending thoracic aorta–abdominal aortic bypass and bilateral renal arterial blood circulation reconstruction are effective in atypical coarctation of the aorta with heart failure: a case report
BackgroundThere are a lot of reports of the renal failure and heart failure due to coarctation of the aorta. However, there are no case reports in...
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Transgenic human C-reactive protein affects oxidative stress but not inflammation biomarkers in the aorta of spontaneously hypertensive rats
BackgroundC-reactive protein (CRP) is an acute inflammatory protein detected in obese patients with metabolic syndrome. Moreover, increased CRP...
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Increased vascular inflammation on PET/CT in psoriasis and the effects of biologic treatment: systematic review and meta-analyses
PurposeThis systematic review and meta-analyses evaluate if aortic vascular inflammation is increased in moderate-severe psoriasis compared to a...
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Effects of local cryotherapy on systemic endothelial activation, dysfunction, and vascular inflammation in adjuvant-induced arthritis (AIA) rats
AimThis study explored the systemic vascular effects of local cryotherapy with a focus on endothelial changes and arterial inflammation in the model...
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NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice
Previous studies suggested a beneficial effect of natriuretic peptides in animal models of cardiovascular disease, but the role of natriuretic...
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Do biologic therapies reduce aortic inflammation in rheumatoid arthritis patients?
ObjectivesRheumatoid arthritis (RA) patients have an increased risk of cardiovascular disease (CVD). In the present study, we evaluated the...
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Diabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization
BackgroundIn observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a...
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Postoperative hyper-inflammation as a predictor of poor outcomes in patients with acute type A aortic dissection (ATAAD) undergoing surgical repair
BackgroundPostoperative hyper-inflammation is a frequent event in patients with acute Stanford type A aortic dissection (ATAAD) after surgical...
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Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)
Purpose of ReviewIn this review, we focus on the clinical and epidemiological studies pertaining to systemic and vascular inflammation by positron...
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Platelets in Kawasaki disease: mediators of vascular inflammation
Kawasaki disease, a systemic vasculitis that affects young children and can result in coronary artery aneurysms, is the leading cause of acquired...
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Distinguishing sterile inflammation from graft infection
We describe the case of a 68-year-old man who underwent ascending aortic replacement and thoracic endovascular aortic repair. Four years later, the...
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Prognostic Value of Systemic Inflammation Response Index in Acute Type A Aortic Dissection
BackgroundThe study aimed to evaluate the prognostic value of preoperative systemic inflammation response index (SIRI) for acute type A aortic...
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Specialized pro-resolving mediators in vascular inflammation and atherosclerotic cardiovascular disease
Timely resolution of the acute inflammatory response (or inflammation resolution) is an active, highly coordinated process that is essential to...