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Etanercept-associated episcleritis: a pediatric case report of a paradoxical adverse reaction and review of the literature
Scleritis is an inflammation of the episcleral and scleral tissues, characterized by injection in both superficial and deep episcleral vessels. When...
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Is PEGylation of Drugs Associated with Hypersensitivity Reactions? An Analysis of the Italian National Spontaneous Adverse Drug Reaction Reporting System
Background and objectiveEvidence highlights the allergenic potential of PEGylated drugs because of the production of anti-polyethylene glycol...
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Outcome of revision surgery for adverse local tissue reactions in patients with recalled total hip arthroplasty
IntroductionRecalls of total hip arthroplasty (THA) implants, including metal-on-metal (MoM) THA and dual taper stems, due to increased risk of...
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Pediatric Drug Safety Surveillance: A 10-Year Analysis of Adverse Drug Reaction Reporting Data in Calabria, Southern Italy
IntroductionThe paucity of pediatric clinical trials has led to many medicines frequently prescribed to children without a license for use in...
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Evaluation of Analgesic Efficacy of Dexmedetomidine as an Adjuvant to Local Anaesthesia in Maxillofacial Soft Tissue Injuries: A Prospective Randomised Clinical Trial
Aims and ObjectivesDexmedetomidine is a relatively new, potent, and highly selective α2-adrenergic receptor agonist used for perioperative...
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Adverse Reactions Associated with Dermal Fillers in the Oral and Maxillofacial Region: A Venezuelan Experience
BackgroundDermal facial fillers are increasingly popular. Published reports on the clinical and histopathologic characteristics related to adverse...
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Adverse effects associated with acupuncture therapies: An evidence map** from 535 systematic reviews
Background and ObjectiveConsidering that physicians and patients widely use acupuncture, it is necessary to explore its adverse effects during...
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Blood transfusion reactions and risk of acute kidney injury and major adverse kidney events
BackgroundBlood transfusion reactions may have a negative impact on organ function. It is unknown whether this association holds true for acute...
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CACA guidelines for holistic integrative management of anticancer treatment - induced cutaneous adverse events
PurposeThe skin and mucous membrane of cancer patients can be directly or indirectly impaired during the treatment of cancers, bringing about not...
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Laser treatment for adverse reactions to injectable facial filling: a systematic review
Facial filling is widespread in society, albeit associated with inherent risks. This review analyzes clinical studies using laser therapy for filler...
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Adverse Events and Device Failures Associated with Pancreatic Stents: A Comprehensive Analysis Using the FDA’s MAUDE Database
IntroductionPancreatic duct stents (PDS) are widely used for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP)...
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Allergic and other adverse reactions to drugs used in anesthesia and surgery
The list of drugs patients may be exposed to during the perioperative and postoperative periods is potentially extensive. It includes induction...
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Novel beagle model of gastric local fibrotic target lesions for the evaluation and training of endoscopic techniques
BackgroundNovel endoscopic techniques used in the treatment of gastric lesions with local submucosal fibrosis need preclinical evaluation and...
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Efficacy of Endoscopic Tissue Adhesive in Patients with Gastrointestinal Tumor Bleeding
BackgroundGastrointestinal tumors bleeding remains a significantly clinical challenge due to its resistance to conventional endoscopic hemostasis...
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Delayed hypersensitivity reaction to cosmetic filler following two COVID-19 vaccinations and infection
BackgroundWith ongoing COVID-19 vaccination schedules and the popularity of cosmetic fillers, it is important to examine and record associated...
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Adverse Reactions to Biologic Medications Used in Allergy and Immunology Diseases
Purpose of ReviewThe use of biologic therapies has risen exponentially over recent years, allowing for unprecedented disease control within numerous...
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Managing Adverse Effects of Novel Therapeutic Agents in Gynecologic Malignancies
Gynecologic cancer treatments have evolved significantly. Several targeted therapies are approved for use in combination with cytotoxic therapy, as...
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A systematic review on the use of quantitative imaging to detect cancer therapy adverse effects in normal-appearing brain tissue
Cancer therapy for both central nervous system (CNS) and non-CNS tumors has been previously associated with transient and long-term cognitive...
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Diagnosis and Management of Dermatologic Adverse Events from Systemic Melanoma Therapies
The advent of protein kinase inhibitors and immunotherapy has profoundly improved the management of advanced melanoma. However, with these...
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Ocular adverse events associated with immune checkpoint inhibitors, a sco** review
IntroductionImmune checkpoint inhibitors (ICIs) have become an important part of the treatment of multiple cancers, especially for advanced melanoma...