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A Gelatin-Based Biomimetic Scaffold Promoting Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells
BackgroundIn bone tissue engineering segment, numerous approaches have been investigated to address critically sized bone defects via 3D scaffolds,...
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Effect of Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells on Human Sperm Quality During Cryopreservation
The cryopreservation procedure decreases sperm quality, causing certain changes at structural and molecular levels affecting fertilizing ability. We...
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Extracellular Vesicles Derived from Auricular Chondrocytes Facilitate Cartilage Differentiation of Adipose-Derived Mesenchymal Stem Cells
PurposeAdipose-derived mesenchymal stem cell (ADSC)-based therapies have been utilized for cartilage regeneration because of their multi-lineage...
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Nintedanib-loaded exosomes from adipose-derived stem cells inhibit pulmonary fibrosis induced by bleomycin
BackgroundPulmonary fibrosis (PF) is a progressive lung disorder with a high mortality rate; its therapy remains limited due to the inefficiency of...
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Evaluation of canine adipose-derived mesenchymal stem cells for neurological functional recovery in a rat model of traumatic brain injury
BackgroundTraumatic brain injury (TBI) is a common condition in veterinary medicine that is difficult to manage.Veterinary regenerative therapy based...
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Anti-inflammatory effect of green photobiomodulation in human adipose-derived mesenchymal stem cells
Photo biomodulation (PBM) as a non-invasive and safe treatment has been demonstrated the anti-inflammatory potential in a variety of cell types,...
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Adipose-derived stem cells applied to ankle pathologies: a systematic review
AbstractThe purpose of this systematic review was to analyze the current use of adipose-derived mesenchymal stem cells (ADMSCs) and present the...
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Human Obesity Attenuates Cardioprotection Conferred by Adipose Tissue–Derived Mesenchymal Stem/Stromal Cells
To explore the impact of obesity on reparative potency of adipose tissue–derived mesenchymal stromal/stem cells (A-MSC) in hypertensive...
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Crosstalk of human coronary perivascular adipose-derived stem cells with vascular cells: role of tissue factor
The coronary perivascular adipose tissue (cPVAT) has been associated to the burden of cardiovascular risk factors and to the underlying vessel...
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Accelerating effect of Shilajit on osteogenic property of adipose-derived mesenchymal stem cells (ASCs)
BackgroundShilajit has been widely used remedy for treating a numerous of illness such as bone defects in Iran traditional folk medicine since...
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Exosomes derived from human adipose mesenchymal stem cells loaded bioengineered three-dimensional amniotic membrane-scaffold-accelerated diabetic wound healing
The occurrence of wounds and defects in the healing process is one of the main challenges in diabetic patients. Herein, we investigated whether...
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Exosomes Derived from Human Adipose-Derived Stem Cells Cannot Distinctively Promote Graft Survival in Cryopreservation Fat Grafting
BackgroundCryopreserved fat has limited clinical applications due to its rapid absorption, high degree of fibrosis, and risk of complications after...
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Topical applications of allogeneic adipose-derived mesenchymal stem cells ameliorate the canine keratoconjunctivitis sicca
BackgroundCanine keratoconjunctivitis sicca (KCS) is predominantly an immune-mediated disease. Current therapy of canine KCS is mainly by...
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Administration of adipose-derived mesenchymal stem cell conditioned medium improves ovarian function in polycystic ovary syndrome rats: involvement of epigenetic modifiers system
BackgroundPolycystic ovary syndrome (PCOS) is a widespread heterogeneous disease that is in association with genetic, epigenetic, endocrine and...
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Transplantation of adipose derived stem cells in diabetes mellitus; limitations and achievements
ObjectivesDiabetes mellitus (DM) is a complex metabolic disease that results from impaired insulin secreting pancreatic β-cells or insulin...
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Effects of Age on the Biological Properties of Cryopreserved Adipose-Derived Stem Cells and ASC-Enriched Fat Grafts
BackgroundDonor age is an important factor affecting the biological characteristics of human adipose-derived stem cells. The aim of this study was to...
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Evaluation of adipose-derived stem cells (ASCS) exosome implantation and platelet-rich fibrin (PRF) on critical long bone defects in Sprague-Dawley rats
IntroductionThis study aimed to assess the efficacy of adipose-derived mesenchymal stem cell exosomes (ASCs exosome) and platelet-rich fibrin (PRF)...
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Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus
BackgroundGestational diabetes mellitus (GDM) is a highly prevalent disease and poses a significant risk to the health of pregnant women. Abdominal...
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Adipose-derived mesenchymal stem cells with hypoxic preconditioning improve tenogenic differentiation
BackgroundAdipose-derived mesenchymal stem cells (ADSCs), as seed cells for tendon tissue engineering, are promising for tendon repair and...
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Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade
Aims/hypothesisImmunomodulators blocking cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) or...