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  1. Role of IL-18 in adipose tissue remodeling and metabolic dysfunction

    Background/objectives

    Proinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects...

    Jaqueline Pereira Lana, Marina Chaves de Oliveira, ... Adaliene Versiani Matos Ferreira in International Journal of Obesity
    Article 08 March 2024
  2. The role of adipose tissue and subsequent liver tissue hypoxia in obesity and early stage metabolic dysfunction associated steatotic liver disease

    Background

    Obesity is linked to several health complication, including Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD). Adipose...

    Annelies Van Eyck, Wilhelmus J. Kwanten, ... Stijn L. Verhulst in International Journal of Obesity
    Article 23 December 2023
  3. Increased epicardial adipose tissue is associated with left atrial mechanical dysfunction in patients with heart failure with mildly reduced and preserved ejection fraction

    Introduction

    Heart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF) is often accompanied by atrial dysfunction. It has...

    M. Lobeek, T. M. Gorter, ... M. Rienstra in Clinical Research in Cardiology
    Article Open access 28 May 2024
  4. The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity

    Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic metabolic homeostasis. Additionally, adipose tissue is a...

    Ibrahim AlZaim, Laura P.M.H de Rooij, ... Joanna Kalucka in Nature Reviews Endocrinology
    Article 25 September 2023
  5. Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms

    Abstract

    Diabetic kidney disease (DKD) is a significant healthcare burden worldwide that substantially increases the risk of kidney failure and...

    Fei Lu, **lei Fan, ... Dexin Yu in Abdominal Radiology
    Article 17 October 2023
  6. Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved

    Recently, compelling evidence points to dysbiosis and disruption of the epithelial intestinal barrier as major players in the pathophysiology of...

    Daniela Rosendo-Silva, Sofia Viana, ... Paulo Matafome in Internal and Emergency Medicine
    Article Open access 04 April 2023
  7. Insulin resistance in adipose tissue and metabolic diseases

    Adipose tissue regulates systemic energy metabolism through adipokine production as well as energy storage and energy supply to other organs in...

    Yukiko Imi, Wataru Ogawa, Tetsuya Hosooka in Diabetology International
    Article 22 December 2022
  8. Macrophage and T cell networks in adipose tissue

    The signals and structure of the tissues in which leukocytes reside critically mould leukocyte function and development and have challenged our...

    Ramiah D. Jacks, Carey N. Lumeng in Nature Reviews Endocrinology
    Article 23 October 2023
  9. White adipose tissue mitochondrial bioenergetics in metabolic diseases

    White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy metabolism. In metabolically unhealthy obesity, adipocytes...

    Rugivan Sabaratnam, Didde Riisager Hansen, Per Svenningsen in Reviews in Endocrine and Metabolic Disorders
    Article 10 August 2023
  10. Severity of adipose tissue dysfunction is associated with progression of pre-diabetes to type 2 diabetes: the Tehran Lipid and Glucose Study

    Background

    The association of prediabetes (Pre-DM) regression and progression with visceral adiposity index (VAI) and adipose tissue dysfunction (ATD)...

    Mohammad Jalali, Zahra Bahadoran, ... Farhad Hosseinpanah in BMC Public Health
    Article Open access 09 January 2024
  11. High visceral adipose tissue area is independently associated with early allograft dysfunction in liver transplantation recipients: a propensity score analysis

    Objectives

    To evaluate the association between adipose tissue distribution and early allograft dysfunction (EAD) in liver transplantation (LT)...

    Guanjie Yuan, Shichao Li, ... Zhen Li in Insights into Imaging
    Article Open access 11 October 2022
  12. Immune cells in adipose tissue microenvironment under physiological and obese conditions

    Purpose

    This review will focus on the immune cells in adipose tissue microenvironment and their regulatory roles in metabolic homeostasis of adipose...

    Yuchen Jiang, Fengying Gong in Endocrine
    Article 28 September 2023
  13. The Different Shades of Thermogenic Adipose Tissue

    Purpose of Review

    By providing a concise overview of adipose tissue types, elucidating the regulation of adipose thermogenic capacity in both...

    Yunwen Hu, Yijie Huang, ... Ben He in Current Obesity Reports
    Article 12 April 2024
  14. Unraveling the complex roles of macrophages in obese adipose tissue: an overview

    Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable plasticity and play pivotal roles in coordinating immune responses...

    Chang Peng, Jun Chen, ... Jia Li in Frontiers of Medicine
    Article 02 January 2024
  15. Butyrate alleviates adipose mitochondrial dysfunction and inflammation in experimental model of polycystic ovarian syndrome by modulating SIRT1-dependent mechanism

    Purpose

    Impaired adipose tissue (AT) remodeling has been suggested as a pathophysiological driver of endocrinometabolic events in polycystic ovarian...

    Kehinde S. Olaniyi, Stephanie E. Areloegbe in Nutrire
    Article 12 June 2024
  16. Epicardial adipose tissue thickness is related to early subclinical myocardial dysfunction, particularly in patients with type 2 diabetes mellitus: a case control study

    Background

    Cardiac myofibrillary dysfunction, which can be measure by echocardiographical s train value, represents an early subclinical manifestation...

    David Eduardo Prestegui-Muñóz, Daniel Rabindranath Benítez-Maldonado, ... Juan Antonio Suárez-Cuenca in BMC Cardiovascular Disorders
    Article Open access 02 December 2022
  17. Berberine ameliorates mesenteric vascular dysfunction by modulating perivascular adipose tissue in diet-induced obese in rats

    Background

    Berberine (BBR) has been found to have antiobesity effects, and obesity can lead to adipose tissue degeneration. As a special adipose...

    Man Wang, Xufang Geng, ... Ding Zhao in BMC Complementary Medicine and Therapies
    Article Open access 25 July 2022
  18. Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases

    With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide....

    Wenxi Fang, Saiyang **e, Wei Deng in Journal of Cardiovascular Translational Research
    Article 17 October 2023
  19. Increased epicardial adipose tissue thickness correlates with endothelial dysfunction in spondyloarthritis

    Introduction

    We aimed to investigate the relationship between epicardial adipose tissue (EAT) thickness, flow-mediated dilation (FMD), and carotid...

    Aicha Ben Tekaya, Takwa Mehmli, ... Leila Abdelmoula in Clinical Rheumatology
    Article 01 July 2022
  20. The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders

    Excessive fat deposition in obese subjects promotes the occurrence of metabolic diseases, such as type 2 diabetes mellitus (T2DM), cardiovascular...

    Rui He, Yong Chen in Current Medical Science
    Article 20 June 2024
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