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Role of IL-18 in adipose tissue remodeling and metabolic dysfunction
Background/objectivesProinflammatory cytokines are increased in obese adipose tissue, including inflammasome key masters. Conversely, IL-18 protects...
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The role of adipose tissue and subsequent liver tissue hypoxia in obesity and early stage metabolic dysfunction associated steatotic liver disease
BackgroundObesity is linked to several health complication, including Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD). Adipose...
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Increased epicardial adipose tissue is associated with left atrial mechanical dysfunction in patients with heart failure with mildly reduced and preserved ejection fraction
IntroductionHeart failure (HF) with mildly reduced and preserved ejection fraction (HFmrEF/HFpEF) is often accompanied by atrial dysfunction. It has...
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The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity
Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic metabolic homeostasis. Additionally, adipose tissue is a...
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Abdominal adipose tissue and type 2 diabetic kidney disease: adipose radiology assessment, impact, and mechanisms
AbstractDiabetic kidney disease (DKD) is a significant healthcare burden worldwide that substantially increases the risk of kidney failure and...
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Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved
Recently, compelling evidence points to dysbiosis and disruption of the epithelial intestinal barrier as major players in the pathophysiology of...
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Insulin resistance in adipose tissue and metabolic diseases
Adipose tissue regulates systemic energy metabolism through adipokine production as well as energy storage and energy supply to other organs in...
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Macrophage and T cell networks in adipose tissue
The signals and structure of the tissues in which leukocytes reside critically mould leukocyte function and development and have challenged our...
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White adipose tissue mitochondrial bioenergetics in metabolic diseases
White adipose tissue (WAT) is an important endocrine organ that regulates systemic energy metabolism. In metabolically unhealthy obesity, adipocytes...
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Severity of adipose tissue dysfunction is associated with progression of pre-diabetes to type 2 diabetes: the Tehran Lipid and Glucose Study
BackgroundThe association of prediabetes (Pre-DM) regression and progression with visceral adiposity index (VAI) and adipose tissue dysfunction (ATD)...
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High visceral adipose tissue area is independently associated with early allograft dysfunction in liver transplantation recipients: a propensity score analysis
ObjectivesTo evaluate the association between adipose tissue distribution and early allograft dysfunction (EAD) in liver transplantation (LT)...
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Immune cells in adipose tissue microenvironment under physiological and obese conditions
PurposeThis review will focus on the immune cells in adipose tissue microenvironment and their regulatory roles in metabolic homeostasis of adipose...
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The Different Shades of Thermogenic Adipose Tissue
Purpose of ReviewBy providing a concise overview of adipose tissue types, elucidating the regulation of adipose thermogenic capacity in both...
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Unraveling the complex roles of macrophages in obese adipose tissue: an overview
Macrophages, a heterogeneous population of innate immune cells, exhibit remarkable plasticity and play pivotal roles in coordinating immune responses...
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Butyrate alleviates adipose mitochondrial dysfunction and inflammation in experimental model of polycystic ovarian syndrome by modulating SIRT1-dependent mechanism
PurposeImpaired adipose tissue (AT) remodeling has been suggested as a pathophysiological driver of endocrinometabolic events in polycystic ovarian...
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Epicardial adipose tissue thickness is related to early subclinical myocardial dysfunction, particularly in patients with type 2 diabetes mellitus: a case control study
BackgroundCardiac myofibrillary dysfunction, which can be measure by echocardiographical s train value, represents an early subclinical manifestation...
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Berberine ameliorates mesenteric vascular dysfunction by modulating perivascular adipose tissue in diet-induced obese in rats
BackgroundBerberine (BBR) has been found to have antiobesity effects, and obesity can lead to adipose tissue degeneration. As a special adipose...
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Epicardial Adipose Tissue: a Potential Therapeutic Target for Cardiovascular Diseases
With increased ageing of the population, cardiovascular disease (CVD) has become the most important factor endangering human health worldwide....
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Increased epicardial adipose tissue thickness correlates with endothelial dysfunction in spondyloarthritis
IntroductionWe aimed to investigate the relationship between epicardial adipose tissue (EAT) thickness, flow-mediated dilation (FMD), and carotid...
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The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders
Excessive fat deposition in obese subjects promotes the occurrence of metabolic diseases, such as type 2 diabetes mellitus (T2DM), cardiovascular...