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Systemic Lupus Erythematosus in Children
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease, that mainly affects skin, joints and kidneys but can affect any organ in the...
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Vascular damage in systemic lupus erythematosus
Vascular disease is a major cause of morbidity and mortality in patients with systemic autoimmune diseases, particularly systemic lupus erythematosus...
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Retinal sublayer analysis in juvenile systemic lupus erythematosus without lupus retinopathy
IntroductionWe aimed to analyze the thicknesses of the retinal sublayer and peripapillary retinal nerve fiber layer (pRNFL) in patients with juvenile...
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Children systemic lupus erythematosus-associated pancreatitis
ObjectiveTo early recognise and improve the prognosis of children systemic lupus erythematosus (cSLE)-associated pancreatitis by summarising and...
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Clinical characteristics of systemic lupus erythematosus patients with adrenal hemorrhage
IntroductionAdrenal hemorrhage (AH) is a rare condition and severe cases can lead to acute adrenal insufficiency with potentially life-threatening...
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Targeting Interferon Signalling in Systemic Lupus Erythematosus: Lessons Learned
The development of new medicines for systemic lupus erythematosus (SLE) has not addressed unmet clinical need, with only three drugs receiving...
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Atherosclerosis in Systemic Lupus Erythematosus
Purpose of the ReviewSystemic lupus erythematosus (SLE) patients are at increased risk of cardiovascular disease (CVD) compared to the general...
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Myocardial fibrosis associates with lupus anticoagulant in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that carries increased risk of cardiovascular disease; however, the underlying...
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Type I interferon pathway in pediatric systemic lupus erythematosus
BackgroundThe role of type I interferon (IFN-I) signaling in systemic lupus erythematosus (SLE) has been well established. However, unanswered...
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Subclinical choroidal involvement in Systemic Lupus Erythematosus
PurposeTo assess the choroidal status of Systemic Lupus Erythematosus (SLE) patients using Optical Coherence Tomography (OCT) and OCT-Angiography.
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Systemic lupus erythematosus: latest insight into etiopathogenesis
Systemic lupus erythematosus (SLE) is a complex autoimmune disorder of unknown etiology. Multifactorial interaction among various susceptible factors...
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Oral Consequences of Systemic Lupus Erythematosus: an Update
Purpose of ReviewSystemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organs that has been associated with various oral...
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Association of Thrombotic Markers With Severity of Pediatric-Onset Systemic Lupus Erythematosus
ObjectiveTo assess the relation of thrombotic markers, thrombomodulin and D-dimer levels to the disease severity in pediatric onset systemic lupus...
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Precision medicine in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that has diverse clinical manifestations, ranging from restricted cutaneous involvement...
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The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever
For more than a century, certain bacterial infections that can breach the skin and mucosal barriers have been implicated as common triggers of...
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No clear influence of treatment escalation on flare prevention in serologically active clinically quiescent patients with systemic lupus erythematosus: a retrospective cohort study
This study aimed to clarify the efficacy and safety of treatment escalation by initiating therapeutic agents in serologically active clinically...
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Salt Behind the Scenes of Systemic Lupus Erythematosus and Rheumatoid Arthritis
Purpose of ReviewSodium is vital for human health. High salt intake is a global health problem and is associated with cardiovascular morbidity and...
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Effect of remission, clinical remission with active serology, and glucocorticoid dosage on the pregnancy outcome of pregnant patients with systemic lupus erythematosus
BackgroundRemission is a key treatment target in systemic lupus erythematosus (SLE) management. Given the direct correlation between lupus flares and...
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Diagnostic challenge of tuberculosis in systemic lupus erythematosus: a case report and literature review
Patients with systemic lupus erythematosus (SLE) are at increased risk of tuberculosis (TB) infection due to immune dysfunction and immunosuppressive...
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Safety and efficacy of telitacicept in refractory systemic lupus erythematosus patients who failed treatment with belimumab
ObjectiveThis study aimed to determine the effect and safety of telitacicept, an antagonist of BLyS/APRIL-mediated B cell activation, in patients...