Search
Search Results
-
The effect of pitavastatin in an ischemic skin flap model in rats
BackgroundThe use of statins as a prophylactic drug for ischemic damage in flap surgery has been suggested in recent years, due to their pleiotropic...
-
Enhanced therapeutic efficacy of doxorubicin/cyclophosphamide in combination with pitavastatin or simvastatin against breast cancer cells
Fighting breast tumors mandates finding different agents devoid of chemotherapy side effects. Repurposing existing drugs, such as statins, presents a...
-
Effects of pitavastatin on atherosclerotic-associated inflammatory biomarkers in people living with HIV with dyslipidemia and receiving ritonavir-boosted atazanavir: a randomized, double-blind, crossover study
BackgroundChronic inflammation has been described in people living with HIV (PLHIV) receiving antiretroviral therapy (ART) despite viral suppression....
-
Pitavastatin: Coronary Atherosclerotic Plaques Changes and Cardiovascular Prevention
Stains remain the first therapeutic approach in patients with dyslipidemia to control plasma lipids levels and cardiovascular risk. Multiple clinical...
-
Impact of pitavastatin on new-onset diabetes mellitus compared to atorvastatin and rosuvastatin: a distributed network analysis of 10 real-world databases
BackgroundStatin treatment increases the risk of new-onset diabetes mellitus (NODM); however, data directly comparing the risk of NODM among...
-
Pitavastatin stimulates retinal angiogenesis via HMG-CoA reductase-independent activation of RhoA-mediated pathways and focal adhesion
BackgroundExcessive angiogenesis of the retina is a key component of irreversible causes of blindness in many ocular diseases. Pitavastatin is a...
-
Effects of Pitavastatin on Lipoprotein Subfractions and Oxidized Low-density Lipoprotein in Patients with Atherosclerosis
It has been demonstrated that pitavastatin can significantly reduce low-density lipoprotein (LDL) cholesterol (LDL-C), but its impact on lipoprotein...
-
Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults
BackgroundMany people infected with hepatitis C virus have comorbidities, including hypercholesterolemia, that are treated with statins. In this...
-
Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet
BackgroundStatins suppress the progression of atherosclerosis by reducing low-density lipoprotein (LDL) cholesterol levels. Pemafibrate (K-877), a...
-
Incidence of new-onset diabetes with 1 mg versus 4 mg pitavastatin in patients at high risk of develo** diabetes during a 3-year follow-up
BackgroundStatin therapy reduces the risk of cardiovascular events across a broad spectrum of patients; however, it increases the risk of new-onset...
-
Protective Effects of Different Classes, Intensity, Cumulative Dose-Dependent of Statins Against Primary Ischemic Stroke in Patients with Type 2 Diabetes Mellitus
Purpose of ReviewThe aim of this study is to investigate the protective effects of different statin classes, intensity, and cumulative dose-dependent...
-
Correction to: Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet
An amendment to this paper has been published and can be accessed via the original article.
-
Personalized management of dyslipidemias in patients with diabetes—it is time for a new approach (2022)
Dyslipidemia in patients with type 2 diabetes (DMT2) is one of the worst controlled worldwide, with only about 1/4 of patients being on the...
-
Optimal statin use for prevention of sepsis in type 2 diabetes mellitus
PurposeTo investigate the dose-dependent protective effects of statins, specific classes of statins, and different intensities of statin use on...
-
Association between anemia and mortality in patients with acute coronary syndrome treated with percutaneous coronary intervention and contemporary lipid-lowering therapy
Despite a clear correlation between anemia and mortality in patients with the acute coronary syndrome (ACS), anemia as a mortality predictor in...
