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Psychogenic non-epileptic seizures (PNES) in the context of concurrent epilepsy – making the right diagnosis
Epilepsy is a risk factor for the development of psychogenic non-epileptic seizures (PNES) and comorbid epilepsy is recognized as a comorbidity in...
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Effectiveness and Tolerability of 12-Month Brivaracetam in the Real World: EXPERIENCE, an International Pooled Analysis of Individual Patient Records
Background and ObjectiveReal-world evidence studies of brivaracetam (BRV) have been restricted in scope, location, and patient numbers. The objective...
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Epidemiology and specific features of shoulder injuries in patients affected by epileptic seizures
PurposeEpileptic seizures can cause multiple shoulder injuries, the most common of which are dislocations, recurrent instability, fractures, and...
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Seizures in Children with Cardiac Disease on Extracorporeal Membrane Oxygenation
BackgroundChildren supported with extracorporeal membrane oxygenation (ECMO) have been shown to be at risk for develo** seizures. However, previous...
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Sentinel seizure heralding Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease
BackgroundIsolated seizure as a manifestation of myelin oligodendrocyte antibody-associated disease (MOGAD) has rarely been reported previously.
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Early identification of seizure freedom with medical treatment in patients with mesial temporal lobe epilepsy and hippocampal sclerosis
BackgroundMesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is usually associated with a poor response to antiseizure medications....
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De novo ADGRV1 variant in a patient with ictal asystole provides novel clues for increased risk of SUDEP
BackgroundVarious cardiac and autonomic manifestations are frequently reported during seizures. Among the seizure-related arrhythmia, ictal...
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Etiological profile of new-onset seizures among adult Egyptians
BackgroundNew-onset seizure (NOS) is defined as the first seizure within a 24-h period ever experienced by the patient. A first-ever seizure can be...
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The well responsiveness of drug-resistant focal seizures in anti-AMPA2 receptor encephalitis to perampanel treatment
Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis is an anti-neuronal surface antigen autoimmune encephalitis...
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Less common phenotypes of myelin oligodendrocyte glycoprotein antibody-related diseases in children deserve more attention
BackgroundTo facilitate the identification of less common clinical phenotypes of myelin oligodendrocyte glycoprotein antibody-associated disease...
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Perampanel as monotherapy or first adjunctive therapy in pediatric and adult patients with epilepsy: the first United States-based phase IV open-label ELEVATE study
ELEVATE (Study 410; NCT03288129) is the first prospective, multicenter, open-label, Phase IV study of perampanel as monotherapy or first adjunctive...
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Recurrent seizures of autoimmune origin: emerging phenotypes
ObjectiveRecurrent seizures of autoimmune origin (AEp) are one of the most frequent causes of recurrent seizures or suspected epilepsy of unknown...
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Autoimmune encephalitis and seizures, cerebrospinal fluid, imaging, and EEG findings: a case series
Antibody-mediated encephalitides constitute a group of inflammatory brain diseases characterized by prominent neuropsychiatric symptoms and are...
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Brivaracetam as Early Add-On Treatment in Patients with Focal Seizures: A Retrospective, Multicenter, Real-World Study
IntroductionIn randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Most...
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Effect of mTOR Inhibitors in Epilepsy Treatment in Children with Tuberous Sclerosis Complex Under 2 Years of Age
IntroductionMechanistic target of rapamycin (mTOR) inhibitors sirolimus and everolimus are an effective therapy for subependymal giant cell...
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Attention deficit hyperactivity disorder in children with epilepsy: a multicenter cross-sectional analysis in China
BackgroundThe diagnosis and treatment of attention deficit hyperactivity disorder (ADHD) comorbid with epilepsy have been insufficiently addressed in...
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Exploring the Evidence for Broad-Spectrum Effectiveness of Perampanel: A Systematic Review of Clinical Data in Generalised Seizures
BackgroundThe effectiveness of adjunctive perampanel has not been systematically assessed in seizure types other than its approved indications of...
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A study of brain functional network and alertness changes in temporal lobe epilepsy with and without focal to bilateral tonic–clonic seizures
BackgroundTemporal lobe epilepsy (TLE) is commonly refractory. Epilepsy surgery is an effective treatment strategy for refractory epilepsy, but...
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Prediction of tuberous sclerosis-associated neurocognitive disorders and seizures via machine learning of structural magnetic resonance imaging
PurposeTuberous sclerosis complex (TSC) is a genetic disorder characterized by multiorgan hamartomas, including cerebral lesions, with seizures as a...
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Seizures and emergency department: characteristics and factors of repeat adult attendees
BackgroundTo identify risk factors and characteristics for the repeated attendance at an emergency department (ED) following a seizure.
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