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Giant cell tumor of bone: a report of two cases with metaphyseal lesions and their progression to the articular surface
Two patients presented to outside providers with joint pain. Both had isolated lytic metaphyseal lesions on plain radiographs that were not noted or...
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Giant retroperitoneal myolipoma mimicking liposarcoma: report of a resected case and review of the literature
Myolipomas are rare tumors that are often difficult to differentiate from liposarcoma. Herein, we report a case of resected giant myolipoma...
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Plexiform fibrohistiocytic tumor: a clinicopathological and immunohistochemical study of 39 tumors, with evidence for a CSF1-producing “null cell” population
Plexiform fibrohistiocytic tumor (PFHT) is a mesenchymal tumor of intermediate malignancy, typically occurring in the superficial soft tissues of...
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Multiple brown tumors: a bone complication due to long-term untreated pseudohypoparathyroidism
Bone lytic lesions are a possible complication of pseudohypoparathyroidism type 1B, in undertreated adult patients. Whole body [18F] F-fluorocholine...
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Giant cell tumor of bone at distal radius suffered more soft tissue recurrence and ultrasonography is effective to detect the soft tissue recurrence
BackgroundSoft tissue recurrence of giant cell tumor of bone (GCTB) is rare. This study aims to provide its prevalence, recurrent locations, risk...
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Giant Cell Tumor of Bone: An Update
Purpose of ReviewTo highlight the new developments in the management of advanced giant cell tumor of bone, a rare locally aggressive benign tumor,...
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Giant growth hormone-secreting pituitary adenomas from the endocrinologist’s perspective
ObjectivesSince giant (≥40 mm) GH-secreting pituitary adenomas are rarely encountered, data on their characteristics and treatment outcomes are...
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Giant adrenal ganglioneuroma in children: a case report
BackgroundGanglioneuromas (GNs) arise from the Schwann cells, ganglion cells, and neuronal tissues, and are extremely rare, slow-growing, benign...
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Absence of multinucleated giant cell reaction as an indicator of tumor progression in oral tongue squamous cell carcinoma
PurposeThe aim of this study was to evaluate the presence and distribution of multinucleated giant cell (MGC) reactions in 61 cases of OTSCC and to...
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Giant gluteal and vesical plexiform neurofibromas in a patient with neurofibromatosis type 1: a case report
BackgroundNeurofibromatosis type 1 is a neurocutaneous genetic disorder caused by mutations in the NF1 gene, resulting in the formation of benign...
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Complete resection of a giant intrapericardial cardiac synovial sarcoma
Synovial sarcoma of the heart is a rare tumor. Herein we would like to report a case of giant intrapericardial cardiac synovial sarcoma that...
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An improved total en bloc spondylectomy for L5 vertebral giant cell tumor through a single-stage posterior approach
PurposeAlthough total en bloc spondylectomy (TES) is strongly recommended for spinal giant cell tumor (GCT), it is extremely difficult to excise a L5...
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A rare case of asymptomatic giant pulmonary hamartoma
BackgroundPulmonary hamartomas are benign lung lesions. Histopathologically, pulmonary hamartoma is composed of varying amounts of mesenchymal...
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Dramatic radiotherapy response of a giant T4 cutaneous squamous cell carcinoma of the scalp with extensive bone destruction: a case report
BackgroundPatients with large cutaneous squamous cell carcinoma of the scalp are a treatment challenge. We report a case of dramatic radiotherapy...
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Genomic medicine advances for brain tumors
Cancer genome profiling has revealed important genetic alterations that serve as prognostic indicators and guides for treatment decisions, enabling...
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A case of BRCA1-mutated giant pancreatic acinar cell carcinoma successfully treated with modified FOLFIRINOX therapy and radical resection
Pancreatic acinar cell carcinoma (PACC) is a rare type of pancreatic cancer; further, its pathogenesis and treatment strategies remain unclear. We...
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Radiomics on radiography predicts giant cell tumor histologic response to denosumab
ObjectiveDenosumab is an established targeted systemic therapy for treatment of giant cell tumor of bone (GCTB). We sought to determine whether...
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Giant Adrenal Myelolipoma and Congenital Adrenal Hyperplasia: a Case Report and Review of the Literature
IntroductionAdrenal myelolipomas (AMs) are rare, benign tumors without endocrine activity comprised of mature adipose and hematopoietic tissue....
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A systematic review of radiomics in giant cell tumor of bone (GCTB): the potential of analysis on individual radiomics feature for identifying genuine promising imaging biomarkers
PurposeTo systematically assess the quality of radiomics research in giant cell tumor of bone (GCTB) and to test the feasibility of analysis at the...
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A giant invasive macroprolactinoma with recurrent nasal bleeding as the first clinical presentation: case report and review of literature
BackgroundGiant prolactinoma (> 4 cm in dimension) is a rare disorder. Invasive macroprolactinoma has the potential to cause base of skull erosion...
