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The Malay version of the caregiver assessment of function and upset instrument (Malay-CAFU): a translation and validation study among informal stroke caregivers
BackgroundPost-stroke complications affect the informal caregivers equally as the stroke survivors, especially those who have a moderate to worst...
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Temperament & Character account for brain functional connectivity at rest: A diathesis-stress model of functional dysregulation in psychosis
The human brain’s resting-state functional connectivity (rsFC) provides stable trait-like measures of differences in the perceptual, cognitive,...
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Functional phenotypes in schizophrenia spectrum disorders: defining the constructs and identifying biopsychosocial correlates using data-driven methods
Functional impairments contribute to poor quality of life in schizophrenia spectrum disorders (SSD). We sought to (Objective I ) define the main...
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Decoding the mitochondrial connection: development and validation of biomarkers for classifying and treating systemic lupus erythematosus through bioinformatics and machine learning
BackgroundSystemic lupus erythematosus (SLE) is a multifaceted autoimmune disease characterized by clinical and pathological diversity. Mitochondrial...
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Development and validation of a nomogram to predict the risk of constipation after lumbar interbody fusion surgery
IntroductionTo understand the incidence of postoperative constipation and the risk factors of constipation in patients with lumbar interbody fusion,...
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Cross-cultural adaptation and validation of a self-reporting tool to assess health-related quality of life for Egyptians with extremity bone sarcomas in childhood or adolescence
BackgroundValidated self-reporting tools are required to evaluate the functional outcome and health-related quality of life (HRQOL) for those who had...
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Development and validation of a competitive risk model in patients with rectal cancer: based on SEER database
BackgroundRectal cancer is one of the most common malignancies. To predict the specific mortality risk of rectal cancer patients, we constructed a...
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Role of resting-state functional MRI in detecting brain functional changes following radiotherapy for head and neck cancer: a systematic review and meta-analysis
PurposeIncreasing evidence implicates changes in brain function following radiotherapy for head and neck cancer as precursors for brain dysfunction....
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Development and validation of a nomogram to predict the risk of sepsis-associated encephalopathy for septic patients in PICU: a multicenter retrospective cohort study
BackgroundPatients with sepsis-associated encephalopathy (SAE) have higher mortality rates and longer ICU stays. Predictors of SAE are yet to be...
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Development and validation of a nomogram-assisted tool to predict potentially reversible cognitive frailty in Chinese community-living older adults
BackgroundCognitive frailty (CF) is a complex and heterogeneous clinical syndrome that indicates the onset of neurodegenerative processes and poor...
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Challenging functional connectivity data: machine learning application on essential tremor recognition
Background and aimsThis paper aimed to investigate the usefulness of applying machine learning on resting-state fMRI connectivity data to recognize...
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Establishment and validation of a CT-based prediction model for the good dissolution of mild chronic subdural hematoma with atorvastatin treatment
PurposeTo develop and validate a prediction model based on imaging data for the prognosis of mild chronic subdural hematoma undergoing atorvastatin...
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First validation study of the living with long term conditions scale (LwLTCs) among English-speaking population living with Parkinson’s disease
IntroductionParkinson’s disease is the second most prevalent neurodegenerative disease, affecting 10 million people worldwide. Health and social care...
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Distance-related functional reorganization predicts motor outcome in stroke patients
BackgroundAnalyzing distance-dependent functional connectivity density (FCD) yields valuable insights into patterns of brain activity. Nevertheless,...
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Delineating functional and molecular impact of ex vivo sample handling in precision medicine
Consistent handling of samples is crucial for achieving reproducible molecular and functional testing results in translational research. Here, we...
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Development and validation of the modified index of fragility in head and neck cancer surgery
BackgroundThis study aims to develop and validate, a clinically useful modified index of fragility (mIFG) to identify patients at risk of fragility...
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Survival nomogram for patients with thymic squamous cell carcinoma, based on the SEER database and an external validation cohort
ObjectiveThis study aimed to construct a nomogram to effectively predict the 3 years and 5 years overall survival of patients with thymic squamous...
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Construction and validation of molecular subtypes of coronary artery disease based on ferroptosis-related genes
BackgroundThis study aims to construct a reliable diagnostic model for coronary artery disease (CAD) patients and explore its potential mechanism by...
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Integrative bioinformatics analysis and experimental validation of key biomarkers for risk stratification in primary biliary cholangitis
BackgroundPrimary biliary cholangitis (PBC) is an autoimmune liver disease, whose etiology is yet to be fully elucidated. Currently, ursodeoxycholic...
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Adaption and validation of the Rwandese version of the Young Mania Rating Scale to measure the severity of a manic or hypomanic episode
BackgroundBipolar Disorder is one of the most incapacitating diseases among young persons, leading to cognitive and functional impairment and raised...