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Lynch-Syndrom
Patients with Lynch syndrome, one of the most common hereditary tumor predisposition syndromes, harbor an increased risk for a broad spectrum of...
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Lynch-Syndrom
Patients with Lynch syndrome, one of the most common hereditary tumor predisposition syndromes, harbor an increased risk for a broad spectrum of...
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Lynch-Syndrom
Patients with Lynch syndrome, one of the most common hereditary tumor predisposition syndromes, harbor an increased risk for a broad spectrum of...
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Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea
BackgroundUvaria chamae (UC) and Olax subscorpioidea (OS) roots are included in traditional anti-cancer remedies and some studies have identified...
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Upgrade Rate and Long-term Outcomes of Lobular Neoplasia
Purpose of ReviewLobular neoplasia is a risk factor for breast cancer development, but its management remains controversial as upgrade rates differ...
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Does an Aspirin a Day Take the MASLD Away?
Although aspirin is deeply rooted in the most ancient history of medicine, the mechanism of action of this drug was only identified a few decades...
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A Sco** Review on Malaria Prevention and Control Intervention in Fragile and Conflict-Affected States (FCAS): A Need for Renewed Focus to Enhance International Cooperation
Malaria is a major public health problem in develo** countries. The burden of malaria in fragile and conflict-affected states (FCAS) is increasing...
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Malaria infection and predictor factors among Chadian nomads’ children
BackgroundIn Chad, malaria remains a significant public health concern, particularly among nomadic populations. Geographical factors and the mobility...
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Statistical analysis plan for the LAKANA trial: a cluster-randomized, placebo-controlled, double-blinded, parallel group, three-arm clinical trial testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1–11-month-old infants in Mali
BackgroundThe Large-scale Assessment of the Key health-promoting Activities of two New mass drug administration regimens with Azithromycin (LAKANA)...
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Do Body Mass Index and Breast Density Impact Cancer Risk Among Women with Lobular Carcinoma In Situ?
PurposeBoth body mass index (BMI) and breast density impact breast cancer risk in the general population. Whether obesity and density represent...
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Restraint stress abates the antioxidant potential of melatonin on dimethyl benz (a) anthracene (DMBA) induced carcinogenesis
Free radical involvement in initiation, promotion and progression of carcinogenesis, implicates that scavengers of free radicals may act as...
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Survivorship care plans and information for rural cancer survivors
PurposeThe purpose of the study was to investigate the amount and type of survivorship care information received by cancer survivors living in rural...
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Uptake of screening and risk-reducing recommendations among women with hereditary breast and ovarian cancer syndrome due to pathogenic BRCA1/2 variants evaluated at a large urban comprehensive cancer center
PurposeCarriers of pathogenic variants in BRCA1 /2 have an elevated lifetime cancer risk warranting high-risk screening and risk-reducing procedures...
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Preventative therapy for breast cancer: a clinical experience
BackgroundBreast Cancer incidence in the UK is estimated to rise to 71,000 per year by 2035. Preventative strategies could significantly reduce this....
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Demographics and Clinical Decision Making in Patients with Germline Moderate Penetrance Non-BRCA Mutations in Breast Cancer Related Genes
BackgroundManagement of pathogenic variants in high penetrance genes related to breast cancer (BC), such as BRCA1 and BRCA2, are well established....
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Modeling of malaria vaccine effectiveness on disease burden and drug resistance in 42 African countries
BackgroundThe emergence of antimalarial drug resistance poses a major threat to effective malaria treatment and control. This study aims to inform...
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Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention
Cancerous tissue transformation develo** usually over years or even decades of life is a highly complex process involving strong stressors damaging...
