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Characteristics of people with epilepsy in three Eastern African countries – a pooled analysis
BackgroundEpilepsy is one of the most common neurological disorders worldwide. Yet, its treatment gap is large in some areas and especially in...
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Neuromodulation for temporal lobe epilepsy: a sco** review
Temporal lobe epilepsy (TLE) is difficult to treat as it is often refractory to treatment. Apart from traditional medical treatment, surgical...
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Effect of opposing needling on motor cortex excitability in healthy participants and in patients with post-stroke hemiplegia: study protocol for a single-blind, randomised controlled trial
BackgroundOpposing needling has an obvious curative effect in the treatment of post-stroke hemiplegia; however, the mechanism of the opposing...
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Knowledge and attitudes of neurologists toward epilepsy surgery: an Italian survey
The current study, conceived with the contribution of the Commission for Epilepsy Surgery of the Italian League Against Epilepsy (LICE) and the...
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Impact of COVID-19 pandemic on physical and mental health status and care of adults with epilepsy in Germany
BackgroundTo mitigate the potential consequences of the coronavirus disease 2019 (COVID-19) pandemic on public life, the German Federal Government...
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The metabolic basis of epilepsy
The brain is a highly energy-demanding organ and requires bioenergetic adaptability to balance normal activity with pathophysiological fuelling of...
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The role of the TNFα-mediated astrocyte signaling pathway in epilepsy
Epilepsy is a common disease in the central nervous system. There is growing evidence that epilepsy is associated with glial cells, including...
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Simultaneous high-resolution whole-brain MR spectroscopy and [18F]FDG PET for temporal lobe epilepsy
PurposePrecise lateralizing the epileptogenic zone in patients with drug-resistant mesial temporal lobe epilepsy (mTLE) remains challenging,...
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An invisible cause of disability: stigma in migraine and epilepsy
ObjectiveOur purpose was to identify the ratio and severity of stigmatization in patients with migraine and epilepsy. We also collected demographic...
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CDKL5 Deficiency Disorder-Related Epilepsy: A Review of Current and Emerging Treatment
Cyclin-dependent kinase-like 5 ( CDKL5 ) deficiency disorder (CDD) is a developmental and epileptic encephalopathy with infantile-onset epilepsy. Most...
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Epilepsy in patients undergoing cardiac surgery with ExtraCorporeal Circulation: case series and description of a peculiar clinical phenotype
BackgroundExtracorporeal circulation (ECC) is now being increasingly used in critical care settings. Epileptic seizures are a recognized but under...
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Headache in people with epilepsy
Epidemiological estimates indicate that individuals with epilepsy are more likely to experience headaches, including migraine, than individuals...
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Late-onset epilepsy and the risk of dementia: a systematic review and meta-analysis
BackgroundPatients with dementia have higher risk of epilepsy. However, it remains not comprehensively evaluated if late-onset epilepsy (LOE) is...
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Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population
BackgroundElderly people with epilepsy are large, but neglected group. Data on the predictive factors for recurrent seizures in the elderly...
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Audiovisual teleconsultation for patients with epilepsy in primary care in rural Germany: a pilot study on feasibility and acceptance
BackgroundIn rural areas, epilepsy patients have limited access to specialist secondary care. Substantial travel and waiting times of several hours...
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Electroencephalogram and heart rate variability features as predictors of responsiveness to vagus nerve stimulation in patients with epilepsy: a systematic review
IntroductionVagus nerve stimulation (VNS) is a mainstay treatment in people with medically refractive epilepsy with a growing interest to identify...
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Autonomic manifestations of epilepsy: emerging pathways to sudden death?
Epileptic networks are intimately connected with the autonomic nervous system, as exemplified by a plethora of ictal (during a seizure) autonomic...
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Examining recruitment feasibility and related outcomes in adults post-stroke
BackgroundThere are limited effective and evidence-based interventions for upper extremity hemiparesis post-stroke. To prepare for an RCT and...
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Levetiracetam Interaction with Direct Oral Anticoagulants: A Pharmacovigilance Study
BackgroundLevetiracetam is widely used in post-stroke epilepsy. However, it is suspected to possess P-glycoprotein (P-gp) induction properties, and...
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Benefits from Exclusion Treatment of Unruptured Brain Arteriovenous Malformations on Epilepsy in Adults
PurposeIn approximately 30% of the patients, brain arteriovenous malformations (bAVMs) are revealed by seizures, which may alter the patients’...
