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Prostate cancer polygenic risk score and prediction of lethal prostate cancer
Polygenic risk scores (PRS) for prostate cancer incidence have been proposed to optimize prostate cancer screening. Prediction of lethal prostate...
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Is multiparametric MRI always needed in biopsy-naïve patients with abnormal digital rectal examination? A single-institutional experience combining clinical and micro-ultrasonography-based factors to optimize prostate cancer detection
PurposeTo assess the diagnostic performance of microultrasound-targeted biopsy (microUSTBx) and systematic biopsy (SBx) in detecting clinically...
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Comparison of Ga-PSMA PET MRI with mpMRI in localization and regional staging of prostate cancer
PurposeTo compare diagnostic accuracy in localization and detection of extraprostatic extension (EPE), seminal vesicle invasion (SVI), lymph node...
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Intensive sampling of the umbra and penumbra improves clinically significant prostate cancer detection and reduces risk of grade group upgrading at radical prostatectomy
PurposeOur objective is to evaluate the clinically significant prostate cancer detection rate of overlap** and perilesional systematic biopsy cores...
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The yin and yang of chromosomal instability in prostate cancer
Metastatic prostate cancer remains an incurable lethal disease. Studies indicate that prostate cancer accumulates genomic changes during disease...
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The lived experience of prostate cancer: 10-year survivor perspectives following contemporary treatment of localized prostate cancer
PurposeStudies relying on standardized instruments to measure patient-centered harms and benefits of cancer treatment may fail to capture important...
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Can contralateral lymph-node metastases be ruled out in prostate cancer patients with only unilaterally positive prostate biopsy?
PurposeOur study evaluated the diagnostic benefits of bilateral pelvic lymphadenectomy in prostate cancer patients with unilaterally positive...
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Urine-derived exosomal PSMA is a promising diagnostic biomarker for the detection of prostate cancer on initial biopsy
PurposeIt is well-established that the lack of accurate diagnostic modalities for prostate cancer (PCa) leads to overdiagnosis and overtreatments....
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A cost-benefit analysis of mass prostate cancer screening
BackgroundProstate cancer (PCa) causes a substantial health and financial burden worldwide, underscoring the need for efficient mass screening...
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Management of bone metastasis in prostate cancer
Progression of bone metastases is the primary cause of death in prostate cancer, and skeletal-related events (SREs), including pathologic fractures,...
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Vaccines as treatments for prostate cancer
Prostate cancer is a leading cause of death in men worldwide. For over 30 years, growing interest has focused on the development of vaccines as...
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Association between patient ethnicity and prostate cancer diagnosis following a prostate-specific antigen test: a cohort study of 730,000 men in primary care in the UK
BackgroundBlack men have higher prostate-specific antigen (PSA) levels and higher prostate cancer incidence and mortality than White men, while Asian...
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Coarse label refinement for improving prostate cancer detection in ultrasound imaging
Purpose:Ultrasound-guided biopsy plays a major role in prostate cancer (PCa) detection, yet is limited by a high rate of false negatives and low...
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Clinically significant prostate cancer (csPCa) detection with various prostate sampling schemes based on different csPCa definitions
BackgroundCombining targeted biopsy (TB) with systematic biopsy (SB) is currently recommended as the first-line biopsy method by the European...
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Prostate cancer presentation and management in the Middle East
BackgroundAlthough prostate cancer is a prevalent malignancy worldwide, its clinical presentation and management in the Middle East are not...
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Evidence-based Prostate Cancer Screening Interventions for Black Men: A Systematic Review
AbstractProstate cancer is the second leading cause of death for men in the U.S. and Black men are twice as likely to die from the disease. However,...
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Digital PET for recurrent prostate cancer: how the technology help
Digital PET is characterized by high sensitivity, spatial and temporal resolution, with growing applications of this technology both in clinical...
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The diagnostic accuracy of micro-ultrasound for prostate cancer diagnosis: a review
PurposeMicro-UltraSound (microUS) is a new imaging modality capable of identifying and targeting suspicious areas, which might further increase the...
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Identification of incidental brain tumors in prostate cancer patients via PSMA PET/CT
PurposeBrain metastases are rare in patients with prostate cancer and portend poor outcome. Prostate-specific membrane antigen positron emission...
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Gastrodin inhibits prostate cancer proliferation by targeting canonical Wnt/β-catenin signaling pathway
Prostate cancer is an epithelial malignant tumor occurring in the prostate and is the most common malignant tumor in the male genitourinary system....
