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Rapid Conversion from Solitary Plasmacytoma with Minimal Skull Marrow Involvement to Symptomatic Multiple Myeloma: a Case Report
Solitary skull plasmacytoma is an uncommon clinical entity, characterized by localized proliferation of neoplastic monoclonal plasma cells. Solitary...
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Cerebral Infarction as the First Manifestation of Multiple Myeloma and AL Amyloidosis: a Case Report
Multiple myeloma and AL (amyloid light chain) amyloidosis refer to plasma cell abnormalities, with multiple organs being affected, most commonly the...
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Unmasking Infection Risks in Multiple Myeloma: Insights from a Retrospective Analysis
Multiple myeloma (MM) has witnessed significant therapeutic advancements through the introduction of proteasome inhibitors and immunomodulators,...
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Cost-Effectiveness of Novel Agent Regimens for Transplant-Eligible Newly Diagnosed Multiple Myeloma Patients in India
BackgroundSurvival outcomes for multiple myeloma have improved dramatically since the introduction of novel therapeutic agents. While these drugs are...
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Comprehensive evaluation of genetic and acquired thrombophilia markers for an individualized prediction of clinical thrombosis in patients with lymphoma and multiple myeloma
Patients diagnosed with lymphoma or multiple myeloma are at elevated risk of venous thromboembolism (VTE). Optimum risk stratification and effective...
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Assessment of inter- and intraobserver agreement for META score in distinguishing osteoporotic from multiple myeloma vertebral fractures
PurposeTo conduct an independent assessment of inter- and intraobserver agreement for the META score as a tool for differentiating osteoporotic...
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Minimal Residual Disease-Adapted Therapy in Multiple Myeloma: Current Evidence and Opinions
Purpose of ReviewMultiple myeloma (MM) is a biologically heterogeneous malignancy with relatively uniform treatment paradigms. This review aims to...
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Bispecific Monoclonal Antibodies in Multiple Myeloma: Data from ASH 2022: A Podcast
The introduction of novel immunotherapies has transformed the treatment landscape in multiple myeloma (MM). The addition of these agents has...
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Effect of prior lenalidomide or daratumumab exposure on hematopoietic stem cell collection and reconstitution in multiple myeloma
BackgroundThe roles of Lenalidomide (Len) and Daratumumab (Dara) in multiple myeloma treatment are well-established, yet their influences on...
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Lymphocyte profile in peripheral blood of patients with multiple myeloma
Multiple myeloma (MM) is a disease which remains incurable. One of the main reasons is a weakened immune system that allows MM cells to survive....
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Pet-radiomics in lymphoma and multiple myeloma: update of current literature
PurposeTo provide a comprehensive overview of the current literature on the applications of PET-based radiomics in patients affected by multiple...
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Bone marrow stromal cells dictate lanosterol biosynthesis and ferroptosis of multiple myeloma
Ferroptosis has been demonstrated a promising way to counteract chemoresistance of multiple myeloma (MM), however, roles and mechanism of bone marrow...
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Incidence of thromboembolism and associated factors in multiple myeloma patients treated with immunomodulatory drugs: a retrospective analysis in Belo Horizonte, Brazil
PurposeThe use of immunomodulators in the treatment of multiple myeloma (MM) patients has been associated with venous thromboembolism (VTE). Due to...
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FOXM1 regulates glycolysis and energy production in multiple myeloma
The transcription factor, forkhead box M1 (FOXM1), has been implicated in the natural history and outcome of newly diagnosed high-risk myeloma (HRMM)...
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The role of minimal residual disease and serum free light chain ratio in the management of multiple myeloma
Multiple myeloma (MM) denotes a cancerous growth characterized by abnormal proliferation of plasma cells. Growing evidence suggests that the...
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Impact of extramedullary multiple myeloma on outcomes with idecabtagene vicleucel
Idecabtagene vicleucel (Ide-cel) has demonstrated excellent efficacy and durable responses in patients with relapsed/refractory multiple myeloma...
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Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation
18 F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET) positivity after first-line treatment with autologous stem cell...
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CREB1 promotes expression of immune checkpoint HLA-E leading to immune escape in multiple myeloma
Multiple myeloma (MM) cells effectively escape anti-tumoral immunity to survive in the tumor microenvironment (TME). Herein, we identify...
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Predicting cytogenetic risk in multiple myeloma using conventional whole-body MRI, spinal dynamic contrast-enhanced MRI, and spinal diffusion-weighted imaging
ObjectivesCytogenetic abnormalities are predictors of poor prognosis in multiple myeloma (MM). This paper aims to build and validate a...
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The emerging therapeutic landscape of relapsed/refractory multiple myeloma
From a historic lens, treatment for patients with relapsed/refractory multiple myeloma (R/R MM) has advanced significantly since the advent of...