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1. Dynamic ¹⁸F-FDG PET imaging of liver lesions: evaluation of a two-tissue compartment model with dual blood input function

   Background

   Dynamic PET with kinetic modeling was reported to be potentially helpful in the assessment of hepatic malignancy. In this study, a kinetic...

   **gnan Wang, Yunwen Shao, ... Li Huo in BMC Medical Imaging

   Article Open access 25 May 2021
   

2. Tetralogy of Fallot regurgitation energetics and kinetics: an intracardiac flow analysis of the right ventricle using computational fluid dynamics

   Repaired Tetralogy of Fallot (rTOF) patients suffer from pulmonary regurgitation and may require pulmonary valve replacement (PVR). Cardiac magnetic...

   Yue-Hin Loke, Ibrahim N. Yildiran, ... Laura Olivieri in The International Journal of Cardiovascular Imaging

   Article 26 April 2024
   

3. On the roles of reproducibility, ethics, and statistical modeling in medical research

   Robert deKemp, Daniel Juneau, ... Rob Beanlands in Journal of Nuclear Cardiology

   Article 13 April 2021
   

4. Water content of the endothelial glycocalyx layer estimated by volume kinetic analysis

   Background

   The water volume of the endothelial glycocalyx layer has been estimated at 0.7 to 1.7 L using tracer methods of unclear value. The present...

   Robert G. Hahn in Intensive Care Medicine Experimental

   Article Open access 10 July 2020
   

5. Effects of dynamic and rigid implantation on biomechanical characteristics of different sagittal alignment lumbar after single- or double-level spinal fixations: a finite-element modeling study

   Background

   Although it is critical to understand the accelerated degeneration of adjacent segments after fusion, the biomechanical properties of the...

   Wei Wang, Chao Kong, ... Shibao Lu in European Journal of Medical Research

   Article Open access 11 December 2023
   

6. Comparison of parametric imaging and SUV imaging with [⁶⁸ Ga]Ga-PSMA-11 using dynamic total-body PET/CT in prostate cancer

   Purpose

   Standardized uptake value (SUV) has been prevalently used to measure [ ⁶⁸ Ga]Ga-PSMA-11 activity in prostate cancer, but it is susceptible to...

   Ruohua Chen, Yee Ling Ng, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging

   Article 04 October 2023
   

7. Exploring the nigrostriatal and digestive interplays in Parkinson’s disease using dynamic total-body [¹¹C]CFT PET/CT

   Purpose

   Dynamic total-body imaging enables new perspectives to investigate the potential relationship between the central and peripheral regions....

   Mei **n, Yihan Wang, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging

   Article 23 February 2024
   

8. In vivo vesicular acetylcholine transporter density in human peripheral organs: an [¹⁸F]FEOBV PET/CT study

   Background

   The autonomic nervous system is frequently affected in some neurodegenerative diseases, including Parkinson’s disease and Dementia with...

   Jacob Horsager, Niels Okkels, ... Per Borghammer in EJNMMI Research

   Article Open access 01 April 2022
   

9. [¹⁸F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT_1A receptors in humans

   Purpose

   F13640 (a.k.a. befiradol, NLX-112) is a highly selective 5-HT _1A receptor ligand that was selected as a PET radiopharmaceutical-candidate...

   Pierre Courault, Sophie Lancelot, ... Luc Zimmer in European Journal of Nuclear Medicine and Molecular Imaging

   Article Open access 19 January 2023
   

10. Pharmacological and metabolic parameters of [¹⁸F]flubrobenguane in clinical imaging populations

    Background

    Cardiac sympathetic nervous system molecular imaging has demonstrated prognostic value. Compared with meta -[ ¹¹ C]hydroxyephedrine, [ ¹⁸ F]flub...

    Braeden A. Mair, Jason G. E. Zelt, ... Benjamin H. Rotstein in Journal of Nuclear Cardiology

    Article 26 July 2023
    

11. False lumen hemodynamics and partial thrombosis in chronic aortic dissection of the descending aorta

    Objectives

    Partial thrombosis of the false lumen (FL) in patients with chronic aortic dissection (AD) of the descending aorta has been associated with...

    Aroa Ruiz-Muñoz, Andrea Guala, ... Jose Rodriguez-Palomares in European Radiology

    Article 06 January 2024
    

12. Quantitation of dynamic total-body PET imaging: recent developments and future perspectives

    Background

    Positron emission tomography (PET) scanning is an important diagnostic imaging technique used in disease diagnosis, therapy planning,...

    Fengyun Gu, Qi Wu in European Journal of Nuclear Medicine and Molecular Imaging

    Article Open access 18 July 2023
    

13. Absolute iodine concentration for dynamic perfusion imaging of the myocardium: improved detection of poststenotic ischaemic in a 3D-printed dynamic heart phantom

    Background

    To investigate the detection capabilities of myocardial perfusion defects of dual-energy computed tomography (CT) technology using...

    Johannes Hammel, Lorenz Birnbacher, ... Daniela Pfeiffer in European Radiology Experimental

    Article Open access 31 October 2022
    

14. First-in-human imaging using [¹¹C]MDTC: a radiotracer targeting the cannabinoid receptor type 2

    Purpose

    We report findings from the first-in-human study of [ ¹¹ C]MDTC, a radiotracer developed to image the cannabinoid receptor type 2 (CB2R) with...

    Yong Du, Jennifer M. Coughlin, ... Martin G. Pomper in European Journal of Nuclear Medicine and Molecular Imaging

    Article 06 March 2023
    

15. Mechanistic physiology-based pharmacokinetic modeling to elucidate vincristine-induced peripheral neuropathy following treatment with novel kinase inhibitors

    Purpose

    Limited information is available regarding the drug–drug interaction (DDI) potential of molecular targeted agents and rituximab plus...

    Venkatesh Pilla Reddy , Adrian J. Fretland, ... Joseph A. Ware in Cancer Chemotherapy and Pharmacology

    Article Open access 02 June 2021
    

16. Can 3D imaging modeling recognize functional tissue and predict liver failure? A retrospective study based on 3D modelling of the major hepatectomies after hepatic modulation

    Background

    Thanks to the introduction of radiomics, 3d reconstruction can be able to analyse tissues and recognise true hypertrophy from...

    Emilio Vicente, Yolanda Quijano, ... Valentina Ferri in BMC Surgery

    Article Open access 18 October 2023
    

17. Tumor-to-blood ratio for assessment of fibroblast activation protein receptor density in pancreatic cancer using [⁶⁸Ga]Ga-FAPI-04

    Purpose

    [ ⁶⁸ Ga]Ga-FAPI PET/CT has been widely used in clinical diagnosis and radiopharmaceutical therapy. In this study, tumor-to-blood ratio (TBR)...

    Ruohua Chen, **nlan Yang, ... Jianjun Liu in European Journal of Nuclear Medicine and Molecular Imaging

    Article 05 November 2022
    

18. A Review of Machine Learning Approaches for Brain Positron Emission Tomography Data Analysis

    Positron emission tomography (PET) imaging has moved forward the development of medical diagnostics and research across various domains, including...

    Ke Xu, Hakmook Kang in Nuclear Medicine and Molecular Imaging

    Article 06 February 2024
    

19. Evaluation of [¹⁸F]F-TZ3108 for PET Imaging of Metabolic-Associated Fatty Liver Disease

    Purpose

    Sigma-1 receptor (Sig-1R), a chaperone that resides at the mitochondrion-associated endoplasmic reticulum (ER) membrane, is an ER stress...

    Peiyi Huang, Zhijun Li, ... Liao Sun in Molecular Imaging and Biology

    Article 15 June 2022
    

20. Parametric Imaging of P-Glycoprotein Function at the Blood–Brain Barrier Using k_E,brain-maps Generated from [¹¹C]Metoclopramide PET Data in Rats, Nonhuman Primates and Humans

    Purpose

    PET imaging using [ ¹¹ C]metoclopramide revealed the importance of P-glycoprotein (P-gp, ABCB1) in mediating the brain-to-blood efflux of...

    Louise Breuil, Myriam El Biali, ... Nicolas Tournier in Molecular Imaging and Biology

    Article 06 October 2023