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Application and Effectiveness of Chinese Medicine in Regulating Immune Checkpoint Pathways
Immunotherapy targeting immune checkpoint molecules has emerged as a key approach in cancer treatment, representing the forefront of antitumor...
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Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends
Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, and PD-L1, novel targeting LAG-3 drugs have also been approved in...
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Immune Priming with Spatially Fractionated Radiation Therapy
Purpose of ReviewThis review aims to summarize the current preclinical and clinical evidence of nontargeted immune effects of spatially fractionated...
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Immune Cell Alterations and PI3K-PKB Pathway Suppression in Patients with Allergic Rhinitis Undergoing Sublingual Immunotherapy
IntroductionOur prior clinical study assessed the efficacy and safety of sublingual immunotherapy (SLIT) with standardized Dermatophagoides farina ...
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Immune Checkpoint Inhibitor-Induced (Type 3) Autoimmune Pancreatitis
Purpose of ReviewImmune checkpoint inhibitors (ICI) have revolutionized cancer care and work primarily by blocking CTLA-4 (cytotoxic...
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Role of echocardiography in patients treated with immune checkpoints inhibitors
Immune-related adverse events occurring in the heart (cardiac immune-related adverse events; irAEs) by immune checkpoint inhibitors (ICIs) include...
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Research progress on anti-tumor immune effect of cryoablation
As one of the local treatments, cryoablation plays an increasingly important role in the comprehensive treatment of malignant tumors with its...
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The role of tumor-associated macrophages in tumor immune evasion
BackgroundTumor growth is closely linked to the activities of various cells in the tumor microenvironment (TME), particularly immune cells. During...
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Immune landscape and response to oncolytic virus-based immunotherapy
Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target...
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Presence of EpsteināBarr virus (EBV) antigens detected by sensitive methods has no influence on local immune environment in diffuse large B cell lymphoma
EBV+ādiffuse large B cell lymphoma (DLBCL) not otherwise specified (NOS) is a new entity confirmed by the World Health Organization (WHO) in 2017. In...
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Targeting the innate immune system in pediatric and adult AML
While the introduction of T cell-based immunotherapies has improved outcomes in many cancer types, the development of immunotherapies for both adult...
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Diagnosis and management of immune checkpoint inhibitor-associated acute kidney injury
Since their introduction into clinical practice a decade ago, immune checkpoint inhibitors (ICIs) have had an overwhelming impact on cancer...
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Immune Cells in Cardiac Injury Repair and Remodeling
Purpose of ReviewImmune cells are emerging as central cellular components of the heart which communicate with cardiac resident cells during...
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Hub gene of disulfidptosis-related immune checkpoints in breast cancer
Disulfidptosis and immune checkpoint genes play an important role in tumor treatment. But there has been less research on the relationship between...
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The TSP1-CD47-SIRPĪ± interactome: an immune triangle for the checkpoint era
The use of treatments, such as programmed death protein 1 (PD1) or cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) antibodies, that loosen the...
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Vitamin D, the immune system, and its relationship with diseases
BackgroundVitamin D is classified as an immunomodulatory hormone that is synthesized because of skin exposure to sunlight. It is known to come into...
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Cancer stem cell-immune cell crosstalk in the tumor microenvironment for liver cancer progression
Crosstalk between cancer cells and the immune microenvironment is determinant for liver cancer progression. A tumor subpopulation called liver cancer...
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The progress of research on immune checkpoint inhibitor resistance and reversal strategies for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in humans, which is prone to recurrence and metastasis and has a poor...
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The expression pattern of immune-related genes and characterization of tumor immune microenvironment: predicting prognosis and immunotherapeutic effects in cutaneous melanoma
BackgroundIncreasing evidences have revealed the tumor immune microenvironment not only has vital impacts on the origin, progression, and metastasis...
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Immune cells: potential carriers or agents for drug delivery to the central nervous system
Drug delivery systems (DDS) have recently emerged as a promising approach for the unique advantages of drug protection and targeted delivery....
