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Sex differences in energy metabolism: natural selection, mechanisms and consequences
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the result of evolutionary adaptations that enable women to resist...
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Glucose management for exercise using continuous glucose monitoring (CGM) and intermittently scanned CGM (isCGM) systems in type 1 diabetes: position statement of the European Association for the Study of Diabetes (EASD) and of the International Society for Pediatric and Adolescent Diabetes (ISPAD) endorsed by JDRF and supported by the American Diabetes Association (ADA)
Physical exercise is an important component in the management of type 1 diabetes across the lifespan. Yet, acute exercise increases the risk of...
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Reassessing the evidence: prandial state dictates glycaemic responses to exercise in individuals with type 1 diabetes to a greater extent than intensity
Recent guidelines suggest that adding anaerobic (high intensity or resistance) activity to an exercise session can prevent blood glucose declines...
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French recommendations for the management of glycogen storage disease type III
The aim of the Protocole National De Diagnostic et de Soins/ French National Protocol for Diagnosis and Healthcare (PNDS) is to provide advice for...
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Carvedilol prevents counterregulatory failure and impaired hypoglycaemia awareness in non-diabetic recurrently hypoglycaemic rats
Aims/hypothesisThis study evaluates whether the non-selective β-blocker, carvedilol, can be used to prevent counterregulatory failure and the...
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Diagnosis and management of gestational diabetes mellitus guidelines by DIPSI (Revised)
Gestational diabetes mellitus (GDM) is diabetes that appears during pregnancy, presenting an opportunity for early testing and care to prevent...
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Dorzagliatin: First Approval
Dorzagliatin (HuaTangNing) is an oral glucokinase activator that is being developed by Hua Medicine for the treatment of type 2 diabetes mellitus...
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Tirzepatide: First Approval
Tirzepatide (Mounjaro™) is a single molecule that combines dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like...
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Breastfeeding at night is rarely followed by hypoglycaemia in women with type 1 diabetes using carbohydrate counting and flexible insulin therapy
Aims/hypothesisHypoglycaemia in association with breastfeeding is a feared condition in mothers with type 1 diabetes. Thus, routine carbohydrate...
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Focus on Metformin: Its Role and Safety in Pregnancy and Beyond
Metformin is used worldwide in the treatment of type 2 diabetes and has been used in the treatment of diabetes in pregnancy since the 1970s. It is...
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Recommendations for Women in Mountain Sports and Hypoxia Training/Conditioning
The (patho-)physiological responses to hypoxia are highly heterogeneous between individuals. In this review, we focused on the roles of sex...
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Insulin detection in diabetes mellitus: challenges and new prospects
Tremendous progress has been made towards achieving tight glycaemic control in individuals with diabetes mellitus through the use of frequent or...
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Poly-Agonist Pharmacotherapies for Metabolic Diseases: Hopes and New Challenges
The use of glucagon-like peptide-1 (GLP-1) receptor-based multi-agonists in the treatment of type 2 diabetes and obesity holds great promise for...
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Automated insulin delivery: benefits, challenges, and recommendations. A Consensus Report of the Joint Diabetes Technology Working Group of the European Association for the Study of Diabetes and the American Diabetes Association
A technological solution for the management of diabetes in people who require intensive insulin therapy has been sought for decades. The last 10...
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Alterations in metabolic flux in migraine and the translational relevance
BackgroundMigraine is a highly prevalent disorder with significant economical and personal burden. Despite the development of effective therapeutics,...
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The metabolome as a diagnostic for maximal aerobic capacity during exercise in type 1 diabetes
Aims/hypothesisOur aim was to characterise the in-depth metabolic response to aerobic exercise and the impact of residual pancreatic beta cell...