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Comprehensive assessment of atypical and anaplastic pediatric meningiomas utilizing national cancer database: a retrospective cohort study
PurposeTo examine demographic and clinical characteristics and their association with survival in grade 2 and 3 pediatric meningiomas in a large...
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Identifying and Treating Those at Risk: Disparities in Rapid Relapse Among TNBC Patients in the National Cancer Database
PurposeThis study was designed to characterize features of rapid relapse TNBC (rrTNBC), an aggressive, poor prognosis breast cancer subset using the...
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Breast Surgical Oncology Epidemiologic Research: A Guide and Comparison of Four National Databases
BackgroundNational databases are a rich source of epidemiologic data for breast surgical oncology research. However, these databases differ in...
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Segmental and extended resections provide comparable survival for clinically node-negative splenic flexure cancer: a propensity score-matched analysis of the National Cancer Database
PurposeThere is an ongoing debate regarding the extent of resection for splenic flexure tumors (SFT). The purpose of this study was to compare...
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Neoadjuvant Therapy for Duodenal and Ampullary Adenocarcinoma: A Systematic Review
BackgroundThe role of systemic therapy in the management of ampullary (AA) and duodenal adenocarcinoma (DA) remains poorly understood. This study...
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Impact of Tumor Size and Management on Survival in Small Gastric Gastrointestinal Stromal Tumors
BackgroundSociety guidelines remain inconsistent on the role of endoscopic and radiographic surveillance as an alternative to surgical resection of...
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Sentinel Lymph Node Biopsy Alone is Adequate for Chemotherapy Decisions in Postmenopausal Early-Stage Hormone-Receptor-Positive, HER2-Negative Breast Cancer with One to Three Positive Sentinel Lymph Nodes
BackgroundThe RxPONDER trial randomized patients with cT1–3N0 hormone receptor-positive, HER2-negative (HR + HER2 − ) breast cancer and one to three...
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MGMT promoter methylation in 1p19q-intact gliomas
ObjectiveStandard-of-care for 1p19q-intact anaplastic gliomas is defined by the international randomized phase III CATNON trial, which found an...
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Low Hospital Volume Is Associated with Higher All-Cause Mortality in Black Women with Triple Negative Breast Cancer
IntroductionThis study examines the association between hospital volume and all-cause mortality in Black women with triple negative breast cancer...
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Surgical resection of T4 colon cancers: an NCDB propensity score-matched analysis of open, laparoscopic, and robotic approaches
Historically, T4 tumors of the colon have been a contraindication to minimally invasive resection. The purpose of this study was to conduct a...
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Advancing personalized prognosis in atypical and anaplastic meningiomas through interpretable machine learning models
PurposeThe primary purpose of this study was to utilize machine learning (ML) models to create a web application that can predict survival outcomes...
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Trends in the surgical management of kidney cancer by tumor stage, treatment modality, facility type, and location
Partial nephrectomy (PN) is an alternative to radical nephrectomy (RN) in the appropriate localized renal tumor. The scope of PN has expanded over...
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Clinico–pathologic factors and survival of patients with breast cancer diagnosed with de novo brain metastasis: a national cancer database analysis
PurposePatients with Breast Cancer (BC) with Brain Metastasis (BCBM) have poor survival outcomes. We aimed to explore the clinico–pathologic and...
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When is neoadjuvant chemotherapy indicated in rectal neuroendocrine tumors? An analysis of the National Cancer Database
BackgroundRectal neuroendocrine tumors (rNET) are rare and challenging to manage. While most patients with small rNET can be definitively treated...
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Validation of the Neoadjuvant Rectal Cancer (NAR) Score for Prognostication Following Total Neoadjuvant Therapy (TNT) for Locally Advanced Rectal Cancer
PurposeThe neoadjuvant rectal cancer (NAR) score is a prognostic tool for locally advanced rectal cancer (LARC) treated with total neoadjuvant...
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Reconsidering the absence of extrapancreatic extension in T staging for pancreatic adenocarcinoma in the AJCC (8th ed) Staging Manual using the National Cancer Database
PurposeAlthough the concept of extrapancreatic extension (EPEx) was removed in the eighth edition of the American Joint Committee on Cancer...
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Survival Benefit with Re-resection and Optimal Time to Re-resection in Gallbladder Cancer: a National Cancer Database Study
PurposeGallbladder cancer is often diagnosed incidentally after cholecystectomy. Most patients will then undergo re-resection for potential residual...
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Trends and disparities in access to minimally invasive distal pancreatectomy (midp): an eight-year analysis from the national cancer database
Laparoscopic and robotic approaches to distal pancreatectomy are becoming the standard of care. The aim of our study was to evaluate the trends of...
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Cirrhosis in intrahepatic cholangiocarcinoma: prognostic importance and impact on survival
ContextCholangiocarcinoma (CCA), a malignancy of the biliary tract epithelium is of increasing importance due to its rising incidence worldwide....