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Expression of RSK4, CD44 and MMP-9 is upregulated and positively correlated in metastatic ccRCC
BackgroundTo investigate the expression and function of RSK4, MMP-9 and CD44 in primary clear cell renal cell carcinoma (primary ccRCC) and...
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The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis
BackgroundWe performed a systematic review and meta-analysis of the Matrix metalloproteinases (MMP)-9 (C1562T), MMP-9 (R279Q), MMP-9 (P574R) and...
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Estradiol-Induced MMP-9 Expression via PELP1-Mediated Membrane-Initiated Signaling in ERα-Positive Breast Cancer Cells
Proline-, glutamic acid–, leucine-rich protein 1 (PELP1) is a novel estrogen receptor (ER) coregulator, demonstrated distinctive characters from...
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Plasma MMP-9 and TIMP-1 levels on ICU admission are associated with 30-day survival
BackgroundMatrix metalloproteinases (MMPs) are involved in systemic inflammatory responses and organ failure. The aim of this study was to evaluate...
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Relationship between Toxoplasma gondii seropositivity and schizophrenia in the Lebanese population: potential implication of genetic polymorphism of MMP-9
BackgroundToxoplasma multiplication and its persistence into the brain cause a local neuroinflammatory reaction, resulting synthesis of...
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Hydrogen Sulfide Ameliorates Heart Aging by Downregulating Matrix Metalloproteinase-9
PurposeAging contributes significantly to cardiovascular diseases and cardiac dysfunction, leading to the upregulation of matrix metalloproteinase-9...
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Effects of ultrasound-guided paravertebral block on MMP-9 and postoperative pain in patients undergoing VATS lobectomy: a randomized, controlled clinical trial
BackgroundLocal anesthesia can reduce the response to surgical stress and decrease the consumption of opioids, which may reduce immunosuppression and...
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Variations of plasma oxidative stress levels in male patients with chronic schizophrenia. Correlations with psychopathology and matrix metalloproteinase-9: a case-control study
BackgroundAccumulating evidence has indicated that oxidative stress (OS) and matrix metalloproteinase-9 (MMP-9) may contribute to the mechanism of...
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Knockdown the moyamoya disease susceptibility gene, RNF213, upregulates the expression of basic fibroblast growth factor and matrix metalloproteinase-9 in bone marrow derived mesenchymal stem cells
Moyamoya disease (MMD) is a chronic, progressive cerebrovascular occlusive disease. Ring finger protein 213 (RNF213) is a susceptibility gene of MMD....
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Clinical significance of matrix metalloproteinase-9 expression in papillary thyroid carcinoma: a meta-analysis
ObjectiveThe purpose of this study was to investigate the relationship between the expression of matrix metalloproteinase-9 (MMP-9) and pathological...
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Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia
BackgroundThe main symptoms of preeclampsia (PE), a specific ailment that develops during pregnancy, are proteinuria and hypertension. The...
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The effects of statin therapy on aneurysm size, growth rate, and matrix metalloproteinases-9 levels in patients with aortic aneurysm: a systematic review and meta-analysis
BackgroundAortic aneurysm enlargement over time causes rupture, which frequently results in death. The family of proteases known as matrix...
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The role of Sirtuin 1 in regulation of fibrotic genes expression in pre-adipocytes
PurposeConsidering inhibition of pre-adipocyte cells differentiation in adipose tissue fibrosis, we aimed to explore whether Sirt1 and Hif-1α in...
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Novel point-of-care biomarkers of the dry anophthalmic socket syndrome: tear film osmolarity and matrix metalloproteinase 9 immunoassay
PurposeTo compare tear film osmolarity (TFO) values and matrix metalloproteinase 9 (MMP-9) levels between anophthalmic sockets and healthy fellow...
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Mendelian Randomization Study of the Relationship Between Serum Matrix Metalloproteinases and the Occurrence of Sepsis
BackgroundObservational studies have shown that matrix metalloproteinases (MMPs) are associated with sepsis. However, it is unknown whether this...
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Sacubitril/valsartan inhibits the proliferation of vascular smooth muscle cells through notch signaling and ERK1/2 pathway
AimsTo explore the role and mechanism of Notch signaling and ERK1/2 pathway in the inhibitory effect of sacubitril/valsartan on the proliferation of...
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Differences in metalloproteinases and their tissue inhibitors in the cerebrospinal fluid are associated with delirium
BackgroundThe aetiology of delirium is not known, but pre-existing cognitive impairment is a predisposing factor. Here we explore the associations...
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Decellularization and enzymatic preconditioning of bovine uterus for improved recellularization
BackgroundUterus tissue engineering aims to repair a dysfunctional uterus that causes infertility, e.g., after significant scarring from benign or...
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Atorvastatin induces downregulation of matrix metalloproteinase-2/9 in MDA-MB-231 triple negative breast cancer cells
Matrix metalloproteinases (MMPs) are a family of endopeptidases, mainly responsible of extracellular tissue remodeling. Abundant expression of MMPs...
