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Comparison of platelet proteomic profiles between children and adults reveals origins of functional differences
BackgroundPlatelets are blood cells responsible for the prevention of blood loss upon vessel wall disruption. It has been demonstrated that platelet...
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Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma
BackgroundThe epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression....
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Fibrinogen measurement by a novel point-of-care device with whole blood: comparison of values against Clauss method
Timely fibrinogen replacement is key to treating critical hemorrhage. Measuring fibrinogen concentration by conventional laboratory tests requires...
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Esophageal cancer cell-derived small extracellular vesicles decrease circulating Tfh/Tfr via sEV-PDL1 to promote immunosuppression
Esophageal cancer (EC) is a deadly malignancy. Small extracellular vesicles (sEVs) with programmed death ligand 1 (sEV-PDL1) induce immune escape to...
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Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology
BackgroundAssisted reproductive technology accounts for an increasing proportion of infertility treatments, and assessments to predict clinical...
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To evaluate the relationship of obstructive sleep apnea with chronic periodontitis and its association with coronary artery disease by assessing serum tumor necrosis factor-α
The periodontal tissue initiates an immune-inflammatory response against bacteria and their products at the site of periodontal infection, and...
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Otoconia Structure After Short- and Long-Duration Exposure to Altered Gravity
Vertebrates use weight-lending otoconia in the inner ear otolith organs to enable detection of their translation during self or imposed movements and...
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Gelatin–PVP dissolving microneedle-mediated therapy for controlled delivery of nifedipine for rapid antihypertension treatment
Nifedipine has exhibited to be the oldest primary drug having promising therapeutic potential for hypertension, angina pectoris, and pre-eclampsia...
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Evaluation of Expression of WNT1 and PTCH Genes in Peripheral Blood of Patients with Odontogenic Cysts and Tumours of the Jaws by Quantitative RT-PCR: A Pilot Study
IntroductionOdontogenic lesions of the maxillofacial region constitute a complex group of lesions with diverse histopathologic types and clinical...
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Exploring the protective effect exhibited by curcumin-loaded coconut oil microemulsion in the experimental models of neurodegeneration: an insight of formulation development, in vitro and in vivo study
BackgroundNeurodegenerative diseases are a major health concern which requires promising drugs with appropriate drug delivery systems. The aim of the...
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Effect of Sperm 26S Proteasome on Embryo Formation and Development in In Vitro Fertilization
The aim of this study was to evaluate the effects of sperm proteasome activity on fertilization outcome and embryo development after IVF. Following...
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Autologous fibrin glue versus sutures for conjunctival autograft in primary pterygium: a randomized clinical trial
PurposeTo describe and compare the autologous fibrin glue and traditional sutures for conjunctival graft attachment in patients undergoing primary...
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Risk factors and prevalence of human African trypanosomiasis in individuals living in remote areas of the republic of Congo
BackgroundHuman African trypanosomiasis (HAT) is one of the world’s classical neglected tropical diseases representing a major public health threat...
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Alpha-defensin as a diagnostic tool in revision total knee arthroplasties with unexpected positive intraoperative cultures and unexpected culture negative intraoperative cultures
PurposeUnexpected-positive-intraoperative-cultures (UPIC) are common in presumed aseptic revision-total-knee-arthroplasties (rTKA). However, the...
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Effect study of exosomes derived from platelet-rich plasma in the treatment of knee cartilage defects in rats
BackgroundThe repair of articular cartilage defects has always been a difficult problem. We aimed to investigate the therapeutic effect of...
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The density of bone marrow mononuclear cells and CD34+ cells in patients with three neurologic conditions
BackgroundThis study aimed to identify the density of mononuclear cells (MNCs) and CD34+ cells in the bone marrow of patients with three neurologic...
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Leukocyte esterase test and alpha-defensin test have similar accuracy for the diagnosis of periprosthetic joint infection
BackgroundThe diagnosis of periprosthetic joint infection (PJI) after total joint replacement remains challenging. Synovial biomarkers are...
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Tissue processing of endoscopic ultrasound-guided fine-needle aspiration specimens from solid pancreatic lesions
Now that tissue cores can be obtained using fine-needle biopsy (FNB) needles, the ways tissues are handled for endoscopic ultrasound-guided...
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Mesenchymal Stem Cell Identification After Delayed Cord Clam**
We sought to determine the feasibility of identifying and quantifying mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) after delayed...
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Exosomal tRF-Leu-AAG-001 derived from mast cell as a potential non-invasive diagnostic biomarker for endometriosis
BackgroundThe diagnosis of endometriosis (EMs) is still based on laparoscopic observation. This study tries to verify whether exosomal tRNA-derived...
