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Positron emission tomography (PET) radiotracers for prostate cancer imaging
Imaging plays an increasing role in prostate cancer diagnosis and staging. Accurate staging of prostate cancer is required for optimal treatment...
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Increased [68Ga]Ga-SST uptake in the uncinate pancreatic process in new digital PET/CT machine and potential association with clinical and histologic factors in NET patients
IntroductionA physiological increase in the uptake of [ 68 Ga]Ga-labeled somatostatin analogues ([ 68 Ga]Ga-SST) PET tracers has been reported in the...
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Theranostic approach in liver cancer: an emerging paradigm to optimize personalized medicine
PurposeThis review aims to focus an update of the state-of-the-art theranostics approach in liver cancer using 131I, 32P, 90Y, 166Ho, and 186/188Re...
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Chemokine receptor–targeted PET/CT provides superior diagnostic performance in newly diagnosed marginal zone lymphoma patients: a head-to-head comparison with [18F]FDG
BackgroundIn patients with marginal zone lymphoma (MZL), [ 18 F]FDG PET/CT provided inconsistent diagnostic accuracy. C-X-C motif chemokine receptor 4...
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Validation of the standardization framework SSTR-RADS 1.0 for neuroendocrine tumors using the novel SSTR‑targeting peptide [18F]SiTATE
ObjectivesSomatostatin receptor positron emission tomography/computed tomography (SSTR-PET/CT) using [ 68 Ga]-labeled tracers is a widely used imaging...
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Lymphoma-Sink Effect in Marginal Zone Lymphoma Based on CXCR4-Targeted Molecular Imaging
PurposeRecent studies investigating a tumor-sink effect in solid tumors reported on decreasing uptake in normal organs in patients with higher tumor...
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Whole-body tumor burden in PET/CT expert review
IntroductionPET/CT whole-body tumor burden (WBTB), as a measure for overall burden of cancer, has been shown bear a strong correlation with...
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Advances of radiolabeled GRPR ligands for PET/CT imaging of cancers
GRPR is a type of seven-transmembrane G-protein coupled receptor that belongs to the bombesin protein receptor family. It is highly expressed in...
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Potential clinical utility of 68Ga-DOTATATE PET/CT for detection and response assessment in cardiac sarcoidosis
BackgroundSomatostatin receptor is expressed in sarcoid granulomas, and preliminary clinical studies have shown that myocardial sarcoidosis can be...
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Photorealistic three-dimensional visualization of fusion datasets: cinematic rendering of PET/CT
PurposeCinematic rendering (CR) is a method of photorealistic 3D visualization of volumetric imaging data. We applied this technique to fusion PET/CT...
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Activity Dose Reduction in 64Cu-DOTATATE PET in Patients with Neuroendocrine Neoplasms: Impact on Image Quality and Lesion Detection Ability
PurposePatients with neuroendocrine neoplasms (NEN) engage in lifelong follow-up with frequent somatostatin receptor PET, e.g . [ 64 Cu]Cu-DOTATATE...
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Endocrinology application of molecular imaging: current role of PET/CT
BackgroundIn recent years, nuclear medicine imaging methods have proven to be of paramount importance in a wide variety of diseases, particularly in...
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Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation
This review article explores the dynamic field of radiopharmaceuticals, where innovative developments arise from combining radioisotopes and...
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Uncovering atherosclerotic cardiovascular disease by PET imaging
Assessing atherosclerosis severity is essential for precise patient stratification. Specifically, there is a need to identify patients with residual...
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Molecular Imaging in Recurrent Prostate Cancer Presented as a Mixed Small Neuroendocrine Tumor/Acinar Adenocarcinoma
Molecular imaging is an important tool for evaluating patients with prostate cancer, including those with hybrid histopathology. Although rare, mixed...
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[68 Ga]Ga-FAPI uptake correlates with the state of chronic kidney disease
PurposeKidney fibrosis leads to a progressive reduction in kidney function ultimately resulting in kidney failure. Diagnostic tools to detect kidney...
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Molecular imaging phenoty** for selecting and monitoring radioligand therapy of neuroendocrine neoplasms
Neuroendocrine neoplasia (NEN) is an umbrella term that includes a widely heterogeneous disease group including well-differentiated neuroendocrine...
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Gastroenteropancreatic neuroendocrine neoplasm imaging: standard reporting templates
PurposeStandardized reporting in radiology has an established role in numerous disease processes, with added benefits in oncology of reduced...
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Effect of the versatile bifunctional chelator AAZTA5 on the radiometal labelling properties and the in vitro performance of a gastrin releasing peptide receptor antagonist
BackgroundGastrin Releasing Peptide receptor (GRPr)-based radioligands have shown great promise for diagnostic imaging of GRPr-positive cancers, such...
