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Real-World Management of Patients with Pulmonary Arterial Hypertension: Insights from EXPOSURE
IntroductionFurther insights into real-world management and outcomes of patients with pulmonary arterial hypertension (PAH) are needed. This interim...
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Primary thromboprophylaxis in cancer outpatients – real-world evidence
IntroductionCancer-associated thrombosis (CAT) is a significant concern among patients with malignant diseases, leading to increased mortality. While...
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Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes: The PIONEER REAL Switzerland Multicentre, Prospective, Observational Study
IntroductionReal-world data provide insight into how medications perform in clinical practice. The PIONEER REAL Switzerland study aimed to understand...
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Real World Evidence (RWE) in der Phytotherapie
BackgroundReal world evidence (RWE) is becoming increasingly important in the evaluation of medical interventions and complements findings from...
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Development of quality assessment tool for systematic reviews and meta-analyses of real-world studies: a Delphi consensus survey
The increasing adoption of real-world studies in healthcare for decision making and planning has further necessitated the need for a specific quality...
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Prevalence of bleeding events in real-world Japanese registry for Percutaneous Ventricular Assist Device
PurposeBleeding complication is a critical risk factor for outcomes of acute heart failure patients requiring mechanical circulatory support (MCS),...
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From Data to Wisdom: Biomedical Knowledge Graphs for Real-World Data Insights
Graph data models are an emerging approach to structure clinical and biomedical information. These models offer intriguing opportunities for novel...
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Early real-world implant experience with a helix-fixation ventricular leadless pacemaker
BackgroundRoughly one in six patients receiving conventional transvenous pacemaker systems experience significant complications within 1 year of...
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Real-World Data on Therapies for Relapsed or Refractory Multiple Myeloma: Key Data from ASH 2023—A Podcast
Immunotherapies have significantly improved outcomes in patients with multiple myeloma yet maintaining a durable response in heavily pretreated...
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Real-world-Daten in der Arzneimittelregulation – aktuelle Entwicklungen und Ausblick
BackgroundReal-world data (RWD) and real-world evidence (RWE) derived from RWD through statistical–epidemiological analyses play a promising and...
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Molnupiravir Use Among Patients with COVID-19 in Real-World Settings: A Systematic Literature Review
IntroductionMolnupiravir (MOV) is an oral antiviral for the treatment of individuals with mild-to-moderate COVID-19 and at high risk of progression...
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Real-World Persistence of Ustekinumab in the Treatment of Inflammatory Bowel Disease
IntroductionThere is an urgent need to understand the long-term real-world effectiveness of ustekinumab (UST) in the treatment of Crohn’s disease...
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Supporting responsive parenting in real-world implementation: minimal effective dose of the Video Interaction Project
BackgroundThe Video Interaction Project (VIP) is a healthcare-based intervention that provides real-time video-feedback of parent-child play and...
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Daridorexant treatment for chronic insomnia: a real-world retrospective single-center study
IntroductionChronic insomnia disorder (CID) significantly impacts well-being and daily functioning. Daridorexant, a double orexin receptor blocker,...
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Outcomes of male patients with HR+/HER2– advanced breast cancer receiving palbociclib in the real-world POLARIS study
PurposeData on treatments for male breast cancer patients are limited owing to rarity and underrepresentation in clinical trials. The real-world...
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Epidemiology and Treatment Patterns of Patients with Vitiligo: A Real-World Analysis
IntroductionVitiligo, a chronic autoimmune skin depigmentation disease with an unpredictable course, has been associated with several comorbid...
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RETFound-enhanced community-based fundus disease screening: real-world evidence and decision curve analysis
Visual impairments and blindness are major public health concerns globally. Effective eye disease screening aided by artificial intelligence (AI) is...
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Renal cell carcinoma: the population, real world, and cost-of-illness
BackgroundThe RCC treatment landscape has evolved dramatically over the past decade. The purpose of this study is to present a real-world data...
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Systematic Literature Review of Real-World Evidence on Baricitinib for the Treatment of Rheumatoid Arthritis
IntroductionBaricitinib, an orally available small-molecule inhibitor of Janus kinase (JAK)1 and JAK2, is indicated to treat active...
