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Biomarker-based staging of Alzheimer disease: rationale and clinical applications
Disease staging, whereby the spatial extent and load of brain pathology are used to estimate the severity of Alzheimer disease (AD), is pivotal to...
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Clinical Correlates of the PET-based Braak Staging Framework in Alzheimer’s Disease
In vivo Alzheimer’s disease diagnosis and staging is traditionally based on clinical features. However, the agreement between clinical and...
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Radiologic T staging of colon cancer: renewed interest for clinical practice
Radiologic imaging, especially MRI, has long been the mainstay for rectal cancer staging and patient selection for neoadjuvant therapy prior to...
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Discrepancy between clinical and pathological staging of laryngeal carcinoma: a dilemma to be solved
ObjectivesThe aim of this study was to investigate the degree of discrepancy between the clinical and pathological staging of laryngeal carcinoma,...
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Does clinical T1N0 GGN really require checking for distant metastasis during initial staging for lung cancer?
BackgroundAccurate clinical staging is crucial for selection of optimal oncological treatment strategies in non-small cell lung cancer (NSCLC)....
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Clinical staging of Anderson-Fabry cardiomyopathy: An operative proposal
As a slowly progressive form of hypertrophic cardiomyopathy (HCM), Anderson-Fabry disease (FD) resembles the phenotype of the most common sarcomeric...
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Correlates of severity in a clinical staging model of schizophrenia: a cross-sectional study among 158 subjects
BackgroundClinical staging has been widely used to predict and optimize the treatment of medical disorders. Different models have been proposed to...
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Evolution of TNM Classification for Clinical Staging of Oral Cancer: The Past, Present and the Future
PurposeThe AJCC (American Joint Committee on Cancer) Cancer Staging Manual, 1st Edition, was published in 1977 which focused on the TNM...
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Clinical staging and the differential risks for clinical and functional outcomes in young people presenting for youth mental health care
BackgroundClinical staging proposes that youth-onset mental disorders develop progressively, and that active treatment of earlier stages should...
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Current Status of Imaging for Breast Cancer Staging
Purpose of ReviewBreast cancer is the most common cancer among women. Accurate clinical staging is important as it guides management and treatment....
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Natural Language Processing Algorithm Used for Staging Pulmonary Oncology from Free-Text Radiological Reports: “Including PET-CT and Validation Towards Clinical Use”
Natural language processing (NLP) can be used to process and structure free text, such as (free text) radiological reports. In radiology, it is...
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Screening and staging of chronic obstructive pulmonary disease with deep learning based on chest X-ray images and clinical parameters
BackgroundChronic obstructive pulmonary disease (COPD) is underdiagnosed with the current gold standard measure pulmonary function test (PFT). A more...
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Clinical impact of whole-body MRI in staging and surveillance of patients with myxoid liposarcoma: a 14-year single-centre retrospective study
ObjectiveTo assess the clinical impact of regular whole-body magnetic resonance imaging (WBMRI) surveillance in myxoid liposarcoma patients.
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Therapeutic impact of 18F-FDG PET/CT for initial staging in patients with clinical stage I and IIA, HER2-positive, or triple-negative breast cancer
PurposeWhile 18 F-FDG PET/CT (FDG-PET/CT) is consensual for clinical stage ≥ IIB breast cancers (BC), its benefit for stage I or IIA HER2+ or...
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Correlation of clinical staging and MRI staging for cervical cancer
BackgroundCervical cancer is a major public health problem for women. Accurate staging may lead to proper management of cervical cancer. We...
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Improving glaucoma staging in clinical practice by combining the ICD-10 glaucoma severity classification system and optical coherence tomography
ObjectiveThe International Classification of Disease, 10th revision (ICD-10) codes used for glaucoma severity classification are based on the 24-2...
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The accuracy of clinical neck staging for p16-positive and negative oropharyngeal cancer and its therapeutic implications
PurposeOropharyngeal squamous cell carcinoma (OPSCC) may be treated with primary surgery or primary (chemo)radiation. While surgery with concurrent...
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Clinical manifestation, staging and prognosis of hepatocellular carcinoma in Gambian patients
BackgroundAs a result of the lack of screening programs and the difficulty in making a proper diagnosis, the majority of hepatocellular carcinoma...
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Clinical relevance of high-risk cytogenetic abnormalities and the second revision of the International Staging System (R2-ISS) in patients with multiple myeloma in clinical practice
High-risk cytogenetic abnormalities (HRCAs) are the most critical factor affecting prognosis in multiple myeloma (MM). However, the clinical...
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Is There Re-staging Surgery Necessity for Borderline Ovarian Tumors
ObjectiveThis study assessed the necessity of surgical re-staging in women with borderline ovarian tumors (BOTs) and evaluated the impact of complete...