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Patients with complex and very-early-onset ATL1-related spastic paraplegia offer insights on genotype/phenotype correlations and support for autosomal recessive forms of SPG3A
Spastic paraplegia type 3A (SPG3A) is the second most common form of hereditary spastic paraplegia (HSP). This autosomal-dominant-inherited motor...
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Serum secretoneurin as a promising biomarker for predicting poor prognosis in intracerebral hemorrhage: A prospective cohort study
ObjectiveSecretoneurin may play a brain-protective role. We aim to discover the relationship between serum secretoneurin levels and severity plus...
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Letter to Editor: Cystic vestibular schwannoma – a subgroup analysis from a comparative study between radiosurgery and microsurgery
This letter evaluates the recent study on the management of cystic vestibular schwannomas (VS) compared to solid VS, focusing on the clinical...
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Normal values for swallow events during endoscopic evaluation of swallowing: a preliminary study
PurposeThe current investigation aimed to establish preliminary normative data for endoscopic swallow studies (FEES). The investigators collected...
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Application of GWAS summary data and drug-induced gene expression profiles of neural progenitor cells in psychiatric drug prioritization analysis
Common psychiatric disorders constitute one of the most substantial healthcare burdens worldwide. However, drug development in psychiatry remains...
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Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number
Neuroligin-3 ( Nlgn3 ) is an autism-associated cell-adhesion molecule that interacts with neurexins and is robustly expressed in both neurons and...
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Artificial intelligence based diagnosis of sulcus: assesment of videostroboscopy via deep learning
PurposeTo develop a convolutional neural network (CNN)-based model for classifying videostroboscopic images of patients with sulcus, benign vocal...
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Oral bacterial genic expression detection in aneurysm wall of a French population sample – preliminary monocentric study
IntroductionThe etiology of brain aneurysms remains poorly understood. Finnish research suggests that oral bacteria might contribute to the...
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Surgical strategy in treatment of metopic synostosis in a single centre experience: technical note and quantitative analysis of the outcomes
PurposeTrigonocephaly is the most common craniosynostosis involving orbits. Although some degree of agreement has been reached regarding surgical...
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Prophylactic antibiotics in sialendoscopy: a randomized clinical trial
ObjectiveAntibiotics have been prescribed routinely in sialendoscopy procedures to reduce the risk of postoperative infection, despite the limited...
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Beneficial Effect of Pretreatment Hyperosmolality on Outcome in Severe Traumatic Brain Injury: Evidence from a South Korean Multicenter Registry and Propensity Score Matching Analysis
BackgroundHyperosmolar therapy has long been a cornerstone in managing increased intracranial pressure and improving outcomes in severe traumatic...
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Microsurgical clip** versus endovascular therapy for treating patients with middle cerebral artery aneurysms presenting with neurological ischemic symptoms
Studies comparing different treatment methods in patients with middle cerebral artery (MCA) aneurysms in different subgroups of onset symptoms are...
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Estrogen receptor beta signaling enhances extinction memory recall for heroin-conditioned cues in a sex- and region-specific manner
Return to use, or relapse, is a major challenge in the treatment of opioid use disorder (OUD). Relapse can be precipitated by several factors,...
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Automated classification of brain MRI reports using fine-tuned large language models
PurposeThis study aimed to investigate the efficacy of fine-tuned large language models (LLM) in classifying brain MRI reports into pretreatment,...
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Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
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High resolution imaging of human development: shedding light on contrast agents
BackgroundVisualizing (micro)vascular structures remains challenging for researchers and clinicians due to limitations in traditional radiological...
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Relationship between stress hyperglycemia ratio and prognosis in patients with aneurysmal subarachnoid hemorrhage: a two-center retrospective study
Previous research have demonstrated that the stress hyperglycemia ratio (SHR) accurately reflects acute hyperglycemic states and correlates with...
