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  1. Interrelationship between thyroid hormones and reduced renal function, a review article

    Background

    Understanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...

    Sadaf Agahi, Atieh Amouzegar, ... Ladan Mehran in Thyroid Research
    Article Open access 15 July 2024
  2. SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study

    A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...

    Ziming Li, Zhengbo Song, ... Shun Lu in Signal Transduction and Targeted Therapy
    Article Open access 15 July 2024
  3. Map** alternative splicing events in colorectal cancer

    Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...

    Yifeng Zheng, Guoqiang Zhong, ... Mingsong Li in Discover Oncology
    Article Open access 15 July 2024
  4. Cardiovascular events in CML patients treated with Nilotinib: validation of the HFA-ICOS baseline risk score

    Background

    The therapeutic landscape of chronic myeloid leukaemia (CML) has been transformed by tyrosine kinase inhibitors (TKI). Nilotinib, showed...

    Fiona Fernando, Maria Sol Andres, ... Dragana Milojkovic in Cardio-Oncology
    Article Open access 15 July 2024
  5. Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme

    The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT...

    Christian Vanhove, Michel Koole, ... Monique Bernsen in European Journal of Nuclear Medicine and Molecular Imaging
    Article 15 July 2024
  6. Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia

    Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...

    Asmaa M. Zahran, Omnia H. El-Badawy, ... Khalid I. Elsayh in Clinical and Experimental Medicine
    Article Open access 15 July 2024
  7. Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses

    Background

    Nivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...

    Yuko Murashima, Shun Yamamoto, ... Ken Kato in Journal of Gastrointestinal Cancer
    Article Open access 15 July 2024
  8. Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice

    Purpose

    Fibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...

    Marco F. Taddio, Suraj Doshi, ... Christine E. Mona in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 15 July 2024
  9. Ethical Implications of Artificial Intelligence in Gastroenterology: The Co-pilot or the Captain?

    Though artificial intelligence (AI) is being widely implemented in gastroenterology (GI) and hepatology and has the potential to be paradigm shifting...

    Nishant Aggarwal, David A. Drew, ... Sushovan Guha in Digestive Diseases and Sciences
    Article 15 July 2024
  10. The 2022 PSOGI International Consensus on HIPEC Regimens for Peritoneal Malignancies: Pseudomyxoma Peritonei

    Background

    The combination of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) constitutes the established standard...

    Shigeki Kusamura, Jean-Baptiste Delhorme, ... Brendan Moran in Annals of Surgical Oncology
    Article 15 July 2024
  11. Postoperative Adverse Events Following Neoadjuvant Therapy and Surgery for Borderline Resectable Pancreatic Cancer in a Phase 2 Clinical Trial (Alliance A021501)

    Background

    Postoperative adverse events (AEs) in patients with borderline resectable pancreatic ductal adenocarcinoma (BR-PC) treated with neoadjuvant...

    Rebecca A. Snyder, Tyler J. Zemla, ... Matthew H. G. Katz in Annals of Surgical Oncology
    Article 15 July 2024
  12. CD147 TagSNP is associated with the vulnerability to lung cancer in the Chinese population: a case–control study

    Background

    Lung cancer, with its high morbidity and mortality, presents a major significant public health challenge. CD147, linked to cancer...

    Yuning **e, Chu Huang, ... Xuemei Zhang in Discover Oncology
    Article Open access 15 July 2024
  13. The multifaceted role of PCSK9 in cancer pathogenesis, tumor immunity, and immunotherapy

    Proprotein convertase subtilisin/kexin type 9 (PCSK9), a well-known regulator of cholesterol metabolism and cardiovascular diseases, has recently...

    Chou-Yi Hsu, Mustafa Nasrat Abdulrahim, ... Mohammed Shnain Ali in Medical Oncology
    Article 15 July 2024
  14. Therapeutic potential of Buddleja Polystachya Fresen (stem and leaves) extracts: antimicrobial and cytotoxic properties for ocular disease management

    This study on Buddleja polystachya highlights its phytochemical composition, antimicrobial activity, and cytotoxic impacts. The study emphasizes the...

    Ali Hendi Alghamdi, Asaad Khalid, ... Magbool E. Oraiby in Discover Oncology
    Article Open access 15 July 2024
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