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Lung Tissue Simulants
Human lung tissue is a complex and highly specialized organ responsible for the exchange of oxygen and carbon dioxide, a process essential for...
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Molecular Dissection of Inflammatory Signals in Acute Lung Injury
During lung injury repair, Alveolar Type (AT) 2 cells can convert into AT1 cells to restore alveolar structure. However, in severe lung disease, AT2...
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Oral delivery of ferroptosis inducers for effective treatment of hepatic fibrosis
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM), which is primarily produced by activated hepatic...
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Therapeutic applications of curcumin nanomedicine formulations in cystic fibrosis
Medicinal applications of turmeric-derived curcumin have been known to mankind for long ages. Its potential in managing “cystic fibrosis” has also...
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A computer aided diagnosis framework for detection and classification of interstitial lung diseases using computed tomography (CT) images
In this research work, a computer aided diagnosis (CAD) system is developed and in which the feature extraction system and the classifier are...
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CSR-NeT: lung segmentation from chest radiographs using transfer learning technique
Chest radiographs are one of the foremost and widely used imaging modalities for extracting visual features from biomedical images for critical...
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Temperature-sensitive hydrogel loaded with DNase I alleviates epidural fibrosis in a mouse model of laminectomy
Excessive epidural fibrosis attached to the dura mater is the major cause of recurrent failed back surgery syndrome after spine surgery. Neutrophil...
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PFAS in PMs might be the escalating hazard to the lung health
Atmospheric particulate matter (PM) is a dominant source of air pollution, in particular, molecules less than 2.5 µm in diameter, endangering human...
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RETRACTED ARTICLE: Restoring microRNA-499-5p Protects Sepsis-Induced Lung Injury Mice Via Targeting Sox6
BackgroundMicroRNAs (miRs) are known to participate in sepsis; hence, we aim to discuss the protective effect of miR-499-5p targeting sex-determining...
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Nanomaterials Mediated Diagnosis of Lung Cancer
Lung cancer is one of the grave diseases and accounts for 18% of cancer-related deaths. It has a high mortality rate due to early metastasis, rapid...
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LPA1 antagonist-derived LNPs deliver A20 mRNA and promote anti-fibrotic activities
Activated fibroblasts are major mediators of pulmonary fibrosis. Fibroblasts are generally found in the connective tissue but upon activation can...
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Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung
Messenger RNA has now been used to vaccinate millions of people. However, the diversity of pulmonary pathologies, including infections, genetic...
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si-Tgfbr1-loading liposomes inhibit shoulder capsule fibrosis via mimicking the protective function of exosomes from patients with adhesive capsulitis
BackgroundAdhesive capsulitis is a common shoulder disorder inducing joint capsule fibrosis and pain. When combined with rotator cuff tear (RCT),...
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Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations
This study aimed to overcome the poor solubility of pterostilbene (PTS) by develo** promising reconstituted proethoniosomes (PENs). The...
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Hepatic macrophages act as a central hub for relaxin-mediated alleviation of liver fibrosis
Relaxin is an antifibrotic peptide hormone previously assumed to directly reverse the activation of hepatic stellate cells for liver fibrosis...
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Transformation of zinc oxide nanoparticles in synthetic lung fluids
Surface coatings, including paints, stains, and sealants, have recently become a focus of “nano-enabled” consumer product engineering. Specifically,...
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Recent applications and strategies in nanotechnology for lung diseases
Lung diseases, including COVID-19 and lung cancers, is a huge threat to human health. However, for the treatment and diagnosis of various lung...
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Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has grown into a global pandemic, and...
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