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Enhanced thermodynamic, pharmacokinetic and theranostic properties of polymeric micelles via hydrophobic core-clustering of superparamagnetic iron oxide nanoparticles
BackgroundSuperparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted...
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Novel pH-sensitive triptolide-loaded micelles: a potential approach to increase anti-tumor activity of the diterpenoid epoxide
Tripterygium wilfordii Hook F, a traditional medicine in China has bioactive but toxic triptolide (TP, a diterpenoid triepoxide) as its main active...
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Multifunctional Gd-CuS loaded UCST polymeric micelles for MR/PA imaging-guided chemo-photothermal tumor treatment
Hepatocellular carcinoma (HCC) is a life-threatening disease for which there is no effective treatment currently. Novel theranostics simultaneously...
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Self-assembled NIPAM–PEG–NIPAM polymeric nanomicelles for the delivery of zinc protoporphyrin: a potential stimuli-triggered cancer treatment approach
Zinc protoporphyrin (ZnPP), known as a heme-oxygenase inhibitor, acts as an anticancer agent mainly by increasing free radical levels in the target...
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Polymeric Membranes for Water Treatment
Today's world is suffering from major problems, one with the supply of clean water or scarcity of freshwater. 90% of the world's water is salty...
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Polymeric micelles for pulmonary drug delivery: a comprehensive review
AbstractRespiratory diseases have remained one of the most common diseases worldwide, in which oral and intravenous administration are the most...
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Rational design of ibuprofen-based redox-responsive anti-cancer polymeric drug delivery systems
An increasing number of studies have demonstrated that inflammation has a close correlation with multiple stages of tumor development, including...
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Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy
Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an...
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Bufalin-loaded vitamin E succinate-grafted chitosan oligosaccharide/RGD-conjugated TPGS mixed micelles inhibit intraperitoneal metastasis of ovarian cancer
BackgroundIntraperitoneal metastasis is one of the major causes of the high mortality rate of ovarian cancer. Bufalin (BU) is an effective component...
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Thermosensitive core-rigid micelles of monomethoxy poly(ethylene glycol)-deoxy cholic acid
BackgroundThermosensitive micelles with rigid cores that exhibit a reversible lower critical solution temperature at 30–35 °C can be applied for drug...
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Comparative in vivo biodistribution and pharmacokinetic evaluation of phenytoin sodium loaded polymeric nanomicelles and marketed phenytoin sodium iv
The biodistribution and pharmacokinetic characteristics of intravenously administered phenytoin sodium-loaded nanomicelles were assessed and compared...
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Anticonvulsant and acute toxicity evaluation of phenytoin sodium–loaded polymeric nanomicelle in MES rat model
An acute seizure is a medical condition which, if untreated, can lead to brain damage and even death. Phenytoin sodium is a second-line drug of...
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Polymeric Materials
Plastics represent one of the most pervasive types of materials in our society. This chapter describes the structure, formation mechanisms, and...
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Poloxamer 407/chitosan micelles can improve α-Tocopherol effect on oral keratinocytes proliferation
This study aimed to produce a Poloxamer 407/Chitosan polymeric system for the controlled release of α-TOC and evaluate its biological properties...
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Therapeutic Uses of TheraCour™ Polymeric Nanomicelles Against Cancer, Infectious Diseases, and More
Recent advances in nanotechnology and biotechnology have contributed to the development of drugs with varying desirable characteristics such as...
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Polymeric surfactants synthesised from palm-based oleic acid as potential biocompatible agents in natural rubber latex compounding
This research aimed to design biocompatible polymeric surfactants as additives to natural rubber latex (NRL) and the mechanical properties of the...
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Polymeric Substances Recycled from Excess Sludge in Wastewater Treatment Plant
Recovery of resources from wastewater, e.g., bioplastics, cellulose, metals, and phosphorus, is one of the most important research objectives in...
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Doxorubicin-loaded polymeric nanoparticles containing ketoester-based block and cholesterol moiety as specific vehicles to fight estrogen-dependent breast cancer
The presented research concerns the preparation of polymer nanoparticles (PNPs) for the delivery of doxorubicin. Several block and statistical...
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Design, development, and drug delivery applications of graphene polymeric nanocomposites and bionanocomposites
Recently, nanotechnology has significantly influenced nanomedicine and drug development, and conveyance. From the polymeric nanoarchitectural and...
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A polymeric nanocarrier that eradicates breast cancer stem cells and delivers chemotherapeutic drugs
BackgroundDrug nanocarriers can markedly reduce the toxicities and side effects of encapsulated chemotherapeutic drugs in the clinic. However, these...
