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Develo** Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction
Human-induced pluripotent stem cell (hiPSC)-derived cardiac patches have been extensively used for treating myocardial infarction and have shown...
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Early initiation of ARBs without blood pressure risk via neutrophil membrane-fused pH-sensitive liposomes to reduce cardiomyocyte apoptosis after acute myocardial infarction
Activation of the local renin–angiotensin system (RAS) promotes cardiomyocyte apoptosis and cardiac remodeling after acute myocardial infarction...
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5-Azacytidine incorporated chitosan/collagen/gold nanoparticle matrix preparation and characterization with potential to repair myocardial infarction
With cardiovascular disease has remained a leading cause of death and treatment modalities for myocardial tissue repair have provided promise and...
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Functional hydrogels for the treatment of myocardial infarction
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it leads to necrosis of numerous cardiomyocytes (CMs),...
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Cardiac aorta-derived extracellular matrix scaffold enhances critical mediators of angiogenesis in isoproterenol-induced myocardial infarction mice
An incapability to improve lost cardiac muscle caused by acute ischemic injury remains the most important deficiency of current treatments to prevent...
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Exosomes derived from mir-214-3p overexpressing mesenchymal stem cells promote myocardial repair
AimsExosomes are known as nanovesicles that are naturally secreted, playing an essential role in stem-mediated cardioprotection. This study mainly...
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MicroRNA-208a silencing against myocardial ischemia/reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes
MicroRNA-208a (miR-208a) plays critical roles in the severe fibrosis and heart failure post myocardial ischemia/reperfusion (IR) injury. MiR-208a...
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Cardiomyocyte-targeted anti-inflammatory nanotherapeutics against myocardial ischemia reperfusion (IR) injury
Myocardial ischemia reperfusion (IR) injury is closely related to the overwhelming inflammation in the myocardium. Herein, cardiomyocyte-targeted...
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Stem cell laden nano and micro collagen/PLGA bimodal fibrous patches for myocardial regeneration
BackgroundAlthough the use of cardiac patches is still controversial, cardiac patch has the significance in the field of the tissue engineered...
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An ultra-sensitive biosensor for circulating microRNA detection with Fe single-atom enhanced cathodic luminol-O2 electrochemiluminescence
Circulating microRNAs (miRNAs) play a pivotal role in the occurrence and development of acute myocardial infarction (AMI), and precise detection of...
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Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials
Extracellular vesicles (EVs) generated from mesenchymal stem cells (MSCs) play an essential role in modulating cell—cell communication and tissue...
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RETRACTED ARTICLE: Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-133a Restrains Myocardial Fibrosis and Epithelial–Mesenchymal Transition in Viral Myocarditis Rats Through Suppressing MAML1
Myocarditis is a disease characterized by localized or diffuse inflammation of the myocardium without efficient treatment. This study explored the...
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Exosome-bearing hydrogels and cardiac tissue regeneration
BackgroundIn recent years, cardiovascular disease in particular myocardial infarction (MI) has become the predominant cause of human disability and...
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Xenogeneic Stem Cell–Induced Cardiac Progenitor Cells Regenerated Infarcted Myocardium in Rat Model
PurposeWe aim to investigate the role of stem cell–based regenerative medicine to repair or regrow the infarcted myocardium and restore normal...
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Monocyte Modulation by Liposomal Alendronate Improves Cardiac Healing in a Rat Model of Myocardial Infarction
AbstractThe ischemic injury in acute myocardial infarction (AMI) activates the innate immunity response in two consecutive phases. Classical...
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Highly conductive multiscale fibre-engineered biomedical patch prepared by electrospinning substrate and in-situ polymerization
Myocardial infarction (MI) is one of the major diseases that threaten human life and health. The construction of cardiac patch by tissue engineering...
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Therapeutic Use of Bioengineered Materials for Myocardial Infarction
Cardiovascular disease is a leading cause of worldwide mortality. Despite the success of current therapies for acute myocardial infarction (MI), many...
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Nanofibers for the Immunoregulation in Biomedical Applications
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the selection of appropriate nanomaterials and preparation...
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3D bioprinting of cardiac tissue: current challenges and perspectives
Demand for donor hearts has increased globally due to cardiovascular diseases. Recently, three-dimensional (3D) bioprinting technology has been aimed...
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Oral nanoparticles containing naringenin suppress atherosclerotic progression by targeting delivery to plaque macrophages
Atherosclerosis is the main cause of ischemic stroke and myocardial infarction diseases. Nanoparticles have shown unique benefits for atherosclerosis...
