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Aptamer-induced in-situ growth of acetylcholinesterase-Cu3(PO4)2 hybrid nanoflowers for electrochemical detection of organophosphorus inhibitors
Enzyme-inorganic hybrid nanoflowers (HNFs) have shown excellent sensing capabilities due to their large specific surface area as well as the...
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In Silico Design of Acetylcholinesterase and Glycogen Synthase Kinase-3β Multi-target Inhibitors
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by multifactorial processes related to different biological targets....
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Molecular Modeling of Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by the loss of recent memory, communication and learning ability,...
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Acetylcholinesterase inhibitors and nanoparticles on Alzheimer’s disease: a review
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease clinically characterized by progressive loss of memory, impairment cognitive...
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Aqueous electrodeposition of (AuNPs/MWCNT–PEDOT) composite for high-affinity acetylcholinesterase electrochemical sensors
In this work, an electrochemical transducing platform constructed from carbonaceous tubes modified with thiophene polymer and gold nanoparticles was...
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Advances Toward the Development of New Therapeutic Strategies Targeting Acetylcholinesterase and Its Remediation Processes
Acetylcholinesterase (AChE) is a serine protease, responsible for finalising the transmission of nerve impulses at cholinergic synapses by hydrolysis...
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Ononin inhibits cerebral ischemia/reperfusion injury via suppression of inflammatory responses in experimental rats and SH-SY5Y cells
The cerebral ischemic stroke is a major type of stroke characterized by brain injury, neurological deficits, and cognitive impairments, which...
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Nonhydrolytic sol–gel synthesized oligosiloxane resin reinforced thiol-ene photocured coatings for the immobilization of acetylcholinesterase
AbstractAcetylcholinesterase (AChE), which is responsible for the hydrolysis of neurotransmitter acetylcholine, is a critical enzyme for the nervous...
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Application of gold nanoparticles for improvement of analytical characteristics of conductometric enzyme biosensors
In the work, the possibility of using nanoparticles of gold (AuNPs) to upgrade bioselective elements of biosensors in order to improve their...
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Response surface methodology-based optimization of Pancratium parvum Dalzell-mediated synthesis of gold nanoparticles with potential biomedical applications
Green nanotechnology is an ever-evolving field of research and development due to an environmentally friendly approach. The present study highlights...
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Nanocarriers and Nano Drug Delivery Therapy in Neuro Diseases
Neurological diseases pose significant challenges in drug delivery due to the complex and delicate nature of the central nervous system (CNS)....
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Removal of an organophosphorus pesticide by engineered silylated graphene oxide
The removal of organophosphorus pesticides is the growing concern. The pesticides are biomagnified in food chain, causing greater health hazards to...
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Preparation and Evaluation of Rivastigmine Liposomes for Intranasal Delivery
The blood-brain barrier (BBB) not only provides protection for the brain but also limits the diagnosis and treatment of neurological disease, because...
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Porous silicon-modified electrode for electrochemical pesticide biosensor
An electrochemical biosensor for organophosphorus pesticides detection has been developed by immobilizing acetylcholinesterase (AChE) enzyme, through...
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Nano-molecularly Imprinted Polymers for Advanced Environmental Monitoring: Synthesis, Applications, and Performance
Molecularly imprinted polymers (MIPs) represent an innovative approach to precise and selective pollutant analysis. However, the recent integration...
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Modern Agriculture and Nanosensors
Scientists and engineers have been inspired to develop innovative strategies to increase agricultural production due to the growing need for food due...
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Modern Agriculture and Nanosensors
Scientists and engineers have been inspired to develop innovative strategies to increase agricultural production due to the growing need for food due...
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Single-atom nanozymes: From bench to bedside
Single-atom nanozymes (SANs) are the new emerging catalytic nanomaterials with enzyme-mimetic activities, which have many extraordinary merits, such...
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Targeted Nano-based Drug Delivery in Alzheimer's Disease and Dementia
Alzheimer's disease (AD), the utmost widespread neurodegenerative illness, contributes to an enormous and expanding healthcare burden and impairs...
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Emerging single-atom nanozymes for catalytic biomedical uses
The past four years have witnessed booming progress in single-atom nanozymes (SANs), one of the newest generations of nanozymes with atomically...
