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Silk fibroin microgels as a platform for cell microencapsulation
Cell microencapsulation has been utilized for years as a means of cell shielding from the external environment while facilitating the transport of...
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Poloxamer 407/chitosan micelles can improve α-Tocopherol effect on oral keratinocytes proliferation
This study aimed to produce a Poloxamer 407/Chitosan polymeric system for the controlled release of α-TOC and evaluate its biological properties...
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Construction of bio-inspired multifunctional triple-layered nanocomposite enhances the cell adhesion and treatment of wound repair
A bio-inspired multifunctional nanocomposite comprises a triple-layer keratin (KER)/collagen (COG)/bioactive glass (BGN) matrix. A fibrous material...
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Silk Nanofibrous Electrospun Scaffold Amplifies Proliferation and Stemness Profile of Mouse Spermatogonial Stem Cells
AbstractElectrospun nanofibrous scaffolds provide a structural microenvironment similar to the native extracellular matrix, which leads to the...
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Do** Gd3+ Ion in PDA-PHBV Coating on Ti6Al4V Alloy for Enhancing Corrosion Resistance and Proliferation of Human Gingival Fibroblasts and Human Umbilical Vein Endothelial Cells
In this study, we fabricated poly(3-hydroxybutyrate-3-hydroxyvalerate) (PHBV) coatings doped with Gd 3+ (1, 5, and 10 × 10 −4 mol/L) on Ti6Al4V alloy...
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Programmable multispecific DNA-origami-based T-cell engagers
Multispecific antibodies have emerged as versatile therapeutic agents, and therefore, approaches to optimize and streamline their design and assembly...
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Viscoelastic and phototunable GelMA-alginate hydrogels for 3D cell culture
In this study, we developed a biocompatible 3D viscoelastic interpenetrating network (IPN) hydrogel that can be stiffened (increasing in elastic...
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A simple method for decellularizing a cell-derived matrix for bone cell cultivation and differentiation
The extracellular matrix regulates cell survival, proliferation, and differentiation. In vitro two-dimensional cell experiments are typically...
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Platinum nanoparticles promote breast cancer cell metastasis by disrupting endothelial barrier and inducing intravasation and extravasation
Breast cancer is a common malignancy in women with disappointing prognosis especially the triple-negative subtype. Recently, nanomedicine becomes a...
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Polymeric biomaterial-inspired cell surface modulation for the development of novel anticancer therapeutics
Immune cell-based therapies are a rapidly emerging class of new medicines that directly treat and prevent targeted cancer. However multiple...
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Sintering temperature effects on nano triphasic bioceramic composite coated 316L SS for corrosion resistance, adhesion strength, and cell proliferation on implants
The present work is mainly accentuated to improve corrosion resistance performance, adhesion strength, biocompatibility, and cell proliferation of...
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Unusual effects of a nanoporous gold substrate on cell adhesion and differentiation because of independent multi-branch signaling of focal adhesions
A variety of cell behaviors, such as cell adhesion, motility, and fate, can be controlled by substrate characteristics such as surface topology and...
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Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials
Extracellular vesicles (EVs) generated from mesenchymal stem cells (MSCs) play an essential role in modulating cell—cell communication and tissue...
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Glioma cell membrane camouflaged cinobufotalin delivery system for combinatorial orthotopic glioblastoma therapy
Glioblastoma (GBM) belongs to the deadliest primary malignancies with high mortality rate and poor prognosis. Over the past decades, less progress...
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Subaqueous 3D stem cell spheroid levitation culture using anti-gravity bioreactor based on sound wave superposition
BackgroundRecently, various studies have revealed that 3D cell spheroids have several advantages over 2D cells in stem cell culture. However,...
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Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas
Activated B-cell-like diffuse large B-cell lymphomas (ABC-DLBCLs) are characterized by constitutive activation of nuclear factor κB driven by the...
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A comprehensive review of the effects of porosity and macro- and micropore formations in porous β-TCP scaffolds on cell responses
The present study comprehensively reviewed the effects of porosity, micropores, and macropores of porous β-TCP scaffold on cell responses. Relevant...
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Multifunctional nanocomposites DDMplusAF inhibit the proliferation and enhance the radiotherapy of breast cancer cells via modulating tumor-promoting factors and metabolic reprogramming
BackgroundTumor-promoting factors (TPF) and metabolic reprogramming are hallmarks of cancer cell growth. This study is designed to combine the newly...
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Wireless electrical–molecular quantum signalling for cancer cell apoptosis
Quantum biological tunnelling for electron transfer is involved in controlling essential functions for life such as cellular respiration and...
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Research progress on tumor whole-cell vaccines prepared with nanoparticles for tumor immunotherapy
Tumor vaccines are a promising approach to activate patient’s own immune system to fight against tumor. Traditional tumor vaccines utilize tumor...