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Human cardiomyocyte-derived exosomes induce cardiac gene expressions in mesenchymal stromal cells within 3D hyaluronic acid hydrogels and in dose-dependent manner
Accomplishing a reliable lineage-specific differentiation of stem cells is vital in tissue engineering applications, however, this need remained...
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20(S)-hydroxycholesterol and simvastatin synergistically enhance osteogenic differentiation of marrow stromal cells and bone regeneration by initiation of Raf/MEK/ERK signaling
Previous studies have demonstrated the significant roles of simvastatin (SVA) and oxysterols in the osteogenesis process. In this study, we evaluate...
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Stem cells and common biomaterials in dentistry: a review study
Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists have spared efforts to determine the role of stem cells...
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14-3-3ε protein-immobilized PCL-HA electrospun scaffolds with enhanced osteogenicity
Adipose-derived mesenchymal stem cells (ASCs) accelerate the osteointegration of bone grafts and improve the efficiency in the formation of uniform...
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Synthesis of SPIO Nanoparticles and the Subsequent Applications in Stem Cell Labeling for Parkinson’s Disease
Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in the midbrain, and the stem cell transplantation method...
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Therapeutic Aspects of Bamboo for Wound Healing
Bamboo has been an integral part of the traditional medicinal system worldwide. Traditionally, almost every part of bamboo has been used for... -
Graphene and its derivatives as support system ingredient for bone fracture repair
Among different strategies for the treatment of bone-related abnormalities, bone regeneration or replacement has been accepted as most successful....
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Cell encapsulated and microenvironment modulating microbeads containing alginate hydrogel system for bone tissue engineering
Functional tissue regeneration using synthetic biomaterials requires proliferation and heterotypic differentiation of stem/progenitor cells within a...
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Classes of Stem Cells: From Biology to Engineering
PurposeThe majority of adult tissues are limited in self-repair and regeneration due to their poor intrinsic regenerative capacity. It is widely...
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Whisker of biphasic calcium phosphate ceramics: Osteo-immunomodulatory behaviors
Immune systems play a critical role in the regulation of bone formation and homeostasis, which arouses a growing interest in the development of...
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Effects of chitosan-glycerol phosphate hydrogel on the maintenance and homing of hAd-MSCs after xenotransplantation into the rat liver
Problems associated with the treatment of liver failure necessitate more research on advanced strategies like cell-based therapy and tissue...
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Bioactive borate glass triggers phenotypic changes in adipose stem cells
A bioactive borate glass, 13-93B3 (B3), has been used successfully in the clinic to treat chronic, nonhealing wounds without scarring. However, the...
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Physico-chemical characterization and in vitro biological study of manganese doped β-tricalcium phosphate-based ceramics for bone regeneration applications
This work evaluates the effects of manganese (Mn) do** on the morpho-structural features, mechanical performance, and in vitro biological response...
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Local nascent protein deposition and remodelling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels
Hydrogels serve as valuable tools for studying cell–extracellular matrix interactions in three-dimensional environments that recapitulate aspects of...
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Peptide- and Protein-Graphene Oxide Conjugate Materials for Controlling Mesenchymal Stem Cell Fate
AbstractStem cells hold great potential in tissue engineering due to their prolonged self-renewal and ability to differentiate into a variety of cell...
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Engineering extracellular vesicles for ROS scavenging and tissue regeneration
Stem cell therapy holds promise for tissue regeneration, yet significant challenges persist. Emerging as a safer and potentially more effective...
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Biodegradable Materials from Natural Origin for Tissue Engineering and Stem Cells Technologies
Tissue engineering is emerging as an interdisciplinary field in biomedical engineering that aims to regenerate new biological material for replacing... -
Biocompatibility of Nanocellulose
Nanocellulose already proved to be a highly relevant material for biomedical applications, ensued by its outstanding mechanical properties and, more... -
Regulation of biological processes by intrinsically chiral engineered materials
Chirality has a key role in the synthesis of biomolecules and the development of life. Although the effects of many chiral molecules or materials on...
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A novel gelatin/chitooligosaccharide/demineralized bone matrix composite scaffold and periosteum-derived mesenchymal stem cells for bone tissue engineering
BackgroundA novel biodegradable scaffold including gelatin (G), chitooligosaccharide (COS), and demineralized bone matrix (DBM) could play a...