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  1. Sodium Butyrate Ameliorates Fluorosis-Induced Neurotoxicity by Regulating Hippocampal Glycolysis In Vivo

    Fluorosis can induce neurotoxicity. Sodium butyrate (SB), a histone deacetylase inhibitor, has important research potential in correcting glucose...

    Yangjie Li, Zhengdong Wang, ... Nan Yan in Biological Trace Element Research
    Article 30 January 2023
  2. Dietary sodium acetate and sodium butyrate improve high-carbohydrate diet utilization by regulating gut microbiota, liver lipid metabolism, oxidative stress, and inflammation in largemouth bass (Micropterus salmoides)

    Background

    Adequate level of carbohydrates in aquafeeds help to conserve protein and reduce cost. However, studies have indicated that...

    Qiao Liu, Liangshun Cheng, ... Song Yang in Journal of Animal Science and Biotechnology
    Article Open access 03 April 2024
  3. Coated sodium butyrate ameliorates high-energy and low-protein diet induced hepatic dysfunction via modulating mitochondrial dynamics, autophagy and apoptosis in laying hens

    Background

    Fatty liver hemorrhagic syndrome (FLHS), a fatty liver disease in laying hens, poses a grave threat to the layer industry, stemming from...

    Sasa Miao, Tianming Mu, ... **aoting Zou in Journal of Animal Science and Biotechnology
    Article Open access 02 February 2024
  4. Potential protective effects of sodium butyrate on glycinin-induced oxidative stress, inflammatory response, and growth inhibition in Cyprinus carpio

    Investigated mitigating effects of sodium butyrate (SB) on the inflammatory response, oxidative stress, and growth inhibition of common carp ( Cyprinus...

    Deng-Lai Li, Si-Ying Liu, ... Li-Fang Wu in Fish Physiology and Biochemistry
    Article 15 December 2023
  5. Sodium butyrate supplementation impacts the gastrointestinal bacteria of dairy calves before weaning

    Abstract

    The objective of this study was to systematically investigate how sodium butyrate (SB) affects the gastrointestinal bacteria in newborn...

    Lu Ma, Yi Yang, ... Dengpan Bu in Applied Microbiology and Biotechnology
    Article 12 April 2023
  6. Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling

    Evidence shows that short-chain fatty acids (SCFAs) play an important role in health maintenance and disease development. In particular, butyrate is...

    GuoYan Wang, SenLin Qin, ... Lu Deng in Cell Death & Disease
    Article Open access 25 April 2023
  7. Dietary sodium butyrate positively modulated intestinal microbial community, but did not promote growth of largemouth bass (Micropterus salmoides)

    This study investigated the effects of dietary sodium butyrate (NaB) on growth, serum biochemical indices, intestine histology, and gut microbiota of...

    **aoqin Li, **a Lin, ... **angJun Leng in Fish Physiology and Biochemistry
    Article 23 January 2024
  8. Synergistic effects of sodium butyrate and sodium propionate on the growth performance, blood biochemistry, immunity, and immune-related gene expression of goldfish (Carassius auratus)

    This research was designed to appraise the single or combined effects of dietary sodium butyrate (SB) and sodium propionate (SP) on growth, serum...

    Mehdi Shamsaie Mehrgan, Seyed Pezhman Hosseini Shekarabi, ... Houman Rajabi Islami in Aquaculture International
    Article 05 August 2022
  9. Proanthocyanidin and sodium butyrate synergistically modulate rat colon carcinogenesis by scavenging free radicals and regulating the COX-2 and APC pathways

    Background

    The purpose of this study was to explore the effects of sodium butyrate (NaB), grape seed proanthocyanidin extract (GSPE), or their...

    Elsayed I. Salim, Sameh M. S. El-Halawany, ... Ezar H. Hafez in The Journal of Basic and Applied Zoology
    Article Open access 16 August 2023
  10. Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets

    Background

    Cholesterol is an essential component of lipid rafts in cell plasma membrane, which exerts a hepatoprotective role against mycotoxin...

    Qiufang Zong, Huan Qu, ... Demin Cai in Journal of Animal Science and Biotechnology
    Article Open access 23 December 2022
  11. Effects of short-chain fatty acid-butyrate supplementation on expression of circadian-clock genes, sleep quality, and inflammation in patients with active ulcerative colitis: a double-blind randomized controlled trial

    Background

    The regulation of the circadian clock genes, which coordinate the activity of the immune system, is disturbed in inflammatory bowel disease...

    Donya Firoozi, Seyed Jalil Masoumi, ... Mahintaj Dara in Lipids in Health and Disease
    Article Open access 13 July 2024
  12. Omics and imaging combinatorial approach reveals butyrate-induced inflammatory effects in the zebrafish gut

    Background

    Prebiotic feed additives aim to improve gut health by influencing the microbiota and the gut barrier. Most studies on feed additives...

    Adrià López Nadal, Jos Boekhorst, ... Sylvia Brugman in Animal Microbiome
    Article Open access 03 March 2023
  13. Dynamic changes in butyrate levels regulate satellite cell homeostasis by preventing spontaneous activation during aging

    The gut microbiota plays a pivotal role in systemic metabolic processes and in particular functions, such as develo** and preserving the skeletal...

    Shujie Chen, Liu**g Huang, ... Liwei **e in Science China Life Sciences
    Article 20 December 2023
  14. Sodium butyrate potentiates insulin secretion from rat islets at the expense of compromised expression of β cell identity genes

    Short-chain fatty acids (SCFAs) produced by the gut microbiota have been well demonstrated to improve metabolic homeostasis. However, the role of...

    Shushu Wang, Miaomiao Yuan, ... Libin Zhou in Cell Death & Disease
    Article Open access 19 January 2022
  15. Exploring the Unexplored Arena: Butyrate as a Dual Communicator in Gut–Brain Axis

    It has been thought lately that gut microbiota plays a predominant role in the neuronal behavior via the gut–brain alliance. The plausible mechanisms...
    Zeel Bhatia, Sunny Kumar, Sriram Seshadri in Probiotics, Prebiotics, Synbiotics, and Postbiotics
    Chapter 2023
  16. Butyrate limits inflammatory macrophage niche in NASH

    Immune cell infiltrations with lobular inflammation in the background of steatosis and deregulated gut-liver axis are the cardinal features of...

    Ankita Sarkar, Priya Mitra, ... Partha Chakrabarti in Cell Death & Disease
    Article Open access 18 May 2023
  17. Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity

    The higher prevalence of metabolic syndrome (MetS) in women after menopause is associated with a decrease in circulating 17β-oestradiol. To explore...

    Qingsong Fu, Tiantian Li, ... **aoyun Zhao in Cell Communication and Signaling
    Article Open access 04 May 2023
  18. Methanol as a co-substrate with CO2 enhances butyrate production in microbial electrosynthesis

    Abstract

    Methanol is a promising feedstock for the bio-based economy as it can be derived from organic waste streams or produced electrochemically...

    Hui Yao, Johanna M. Rinta-Kanto, ... Marika Kokko in Applied Microbiology and Biotechnology
    Article Open access 14 June 2024
  19. Impact of graded levels of coated calcium butyrate on growth performance and serological indices during pre-weaning stage in Holstein calves

    The study aimed to analyze the impact of calcium butyrate supplementation in calf starter on growth performance indices associated with early rumen...

    Abdur Rahman, Muhammad Furhan Arshad, ... Muhammad Zeeshan Anwar in Tropical Animal Health and Production
    Article 05 October 2023
  20. Effect of Sodium Butyrate on Proliferative Signaling Cascades in Sensitive and Resistant to Histone Deacetylase Inhibitors Cells

    Abstract

    To establish the mechanisms of transformed cells resistance to the histone deacetylase inhibitors (HDACi), we compared the changes of the...

    O. O. Gnedina, M. V. Igotti in Cell and Tissue Biology
    Article 01 May 2021
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