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Scoary2: rapid association of phenotypic multi-omics data with microbial pan-genomes
Unraveling bacterial gene function drives progress in various areas, such as food production, pharmacology, and ecology. While omics technologies...
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Transcription factor encoding gene OsC1 regulates leaf sheath color through anthocyanidin metabolism in Oryza rufipogon and Oryza sativa
Carbohydrates, proteins, lipids, minerals and vitamins are nutrient substances commonly seen in rice grains, but anthocyanidin, with benefit for...
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OsLSC6 Regulates Leaf Sheath Color and Cold Tolerance in Rice Revealed by Metabolite Genome Wide Association Study
Plant metabolites including anthocyanins play an important role in the growth of plants, as well as in regulating biotic and abiotic stress responses...
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Serum metabolic profile and metabolome genome-wide association study in chicken
BackgroundChickens provide globally important livestock products. Understanding the genetic and molecular mechanisms underpinning chicken economic...
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Metabolite-Based Genome-Wide Association Studies of Large-Scale Metabolome Analysis to Illustrate Alterations in the Metabolite Landscape of Plants upon Responses to Stresses
Given that anthropogenic activities are evoking a profound effect on the climate resulting in more extreme events such as severe drought and heat...
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Metabolomics as a Selection Tool for Abiotic Stress Tolerance in Crops
Abiotic stresses cause aberrations in plant primary metabolism which alters the cell homeostasis. Plants try to maintain the metabolic homeostasis...
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Metabolic GWAS-based dissection of genetic basis underlying nutrient quality variation and domestication of cassava storage root
BackgroundMetabolites play critical roles in regulating nutritional qualities of plants, thereby influencing their consumption and human health....
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Host genetics and gut microbiota jointly regulate blood biochemical indicators in chickens
AbstractBlood biochemical indicators play a crucial role in assessing an individual’s overall health status and metabolic function. In this study, we...
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Population analysis reveals the roles of DNA methylation in tomato domestication and metabolic diversity
DNA methylation is an important epigenetic marker, yet its diversity and consequences in tomato breeding at the population level are largely unknown....
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Characterization of novel loci controlling seed oil content in Brassica napus by marker metabolite-based multi-omics analysis
BackgroundSeed oil content is an important agronomic trait of Brassica napus ( B. napus ), and metabolites are considered as the bridge between...
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Identification and validation of seed dormancy loci and candidate genes and construction of regulatory networks by WGCNA in maize introgression lines
Key messageSeventeen PHS-QTLs and candidate genes were obtained, including eleven major loci, three under multiple environments and two with...
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Common and specific genetic basis of metabolite-mediated drought responses in rice
Plants orchestrate drought responses at metabolic level but the genetic basis remains elusive in rice. In this study, 233 drought-responsive...
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Genome-wide association map** reveals genes underlying population-level metabolome diversity in a fungal crop pathogen
BackgroundFungi produce a wide range of specialized metabolites (SMs) involved in biotic interactions. Pathways for the production of SMs are often...
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Metabolic-GWAS provides insights into genetic architecture of seed metabolome in buckwheat
BackgroundBuckwheat ( Fagopyrum spp.), belonging to the Polygonaceae family, is an ancient pseudo-cereal with high nutritional and nutraceutical...
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A metabolic perspective of selection for fruit quality related to apple domestication and improvement
BackgroundApple is an economically important fruit crop. Changes in metabolism accompanying human-guided evolution can be revealed using a multiomics...
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Combined nature and human selections reshaped peach fruit metabolome
BackgroundPlant metabolites reshaped by nature and human beings are crucial for both their lives and human health. However, which metabolites respond...
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5M approach to decipher starch–lipid interaction in minor millets
Key MessageThe 5M approach can be applied to understand genetic complexity underlying nutritional traits of minor millets. It will help to...
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Integrating multiomics data accelerates elucidation of plant primary and secondary metabolic pathways
Plants are the most important sources of food for humans, as well as supplying many ingredients that are of great importance for human health....
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Metabolomics: a systems biology approach for enhancing heat stress tolerance in plants
Key messageComprehensive metabolomic investigations provide a large set of stress-related metabolites and metabolic pathways, advancing crops under...
