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Ferroptosis: a new hunter of hepatocellular carcinoma
Ferroptosis is an iron ion-dependent, regulatory cell death modality driven by intracellular lipid peroxidation that plays a key role in the...
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Risk prediction for dermatomyositis-associated hepatocellular carcinoma
ObjectiveTo explore dermatomyositis signature genes as potential biomarkers of hepatocellular carcinoma and their associated molecular regulatory...
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β-Sitosterol alleviates the malignant phenotype of hepatocellular carcinoma cells via inhibiting GSK3B expression
To explore the effects of β-Sitosterol upon hepatocellular carcinoma cell proliferation, apoptosis, migration, invasion, and epithelial–mesenchymal...
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Kinesin family member 11 promotes progression of hepatocellular carcinoma via the OCT4 pathway
Hepatocellular carcinoma (HCC) is the tumor with the second highest mortality rate worldwide. Recent research data show that KIF11, a member of the...
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Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3
BackgroundHepatocellular carcinoma (HCC) is a common cancer worldwide, and sorafenib is a first-line drug for the treatment of advanced liver cancer....
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MicroRNA miR-20a-5p targets CYCS to inhibit apoptosis in hepatocellular carcinoma
Hepatocellular carcinoma is a primary liver cancer, characterised by diverse etiology, late diagnoses, and poor prognosis. Hepatocellular carcinoma...
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USP1 modulates hepatocellular carcinoma progression via the Hippo/TAZ axis
Hepatocellular carcinoma (HCC) is one of the most lethal malignancies worldwide. The Hippo signaling pathway has emerged as a significant suppressive...
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HOXD3 promotes the migration and angiogenesis of hepatocellular carcinoma via modifying hepatocellular carcinoma cells exosome-delivered CCR6 and regulating chromatin conformation of CCL20
Angiogenesis plays an essential role in the microenvironment of hepatocellular carcinoma (HCC). HOXD3 is involved in the metastasis and invasion of...
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LincRNA ZNF529-AS1 inhibits hepatocellular carcinoma via FBXO31 and predicts the prognosis of hepatocellular carcinoma patients
BackgroundInvasion and metastasis of hepatocellular carcinoma (HCC) is still an important reason for poor prognosis. LincRNA ZNF529-AS1 is a recently...
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Ferroptosis: a new promising target for hepatocellular carcinoma therapy
Hepatocellular carcinoma (HCC) is the sixed most common malignant tumor in the world. The study for HCC is mired in the predicament confronted with...
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Exploring the Prognostic Features of Hepatocellular Carcinoma via Text Mining and Data Analysis
AbstractTranscatheter arterial chemoembolization is one of the interventional treatments for hepatocellular carcinoma (HCC). This treatment is...
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Molecular characterization of plasma virome of hepatocellular carcinoma (HCC) patients
Hepatocellular carcinoma (HCC) stands as the most common cancer type, arising from various causes, and responsible for a substantial number of...
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ZNF281 inhibits mitochondrial biogenesis to facilitate metastasis of hepatocellular carcinoma
Zinc finger protein 281 (ZNF281) has been shown to promote tumor progression. However, the underlying mechanism remains to be further elucidated. In...
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A Symbolic Regression Approach to Hepatocellular Carcinoma Diagnosis Using Hypermethylated CpG Islands in Circulating Cell-Free DNA
Hepatocellular carcinoma is the most common primary liver cancer, accounting for 90% of cases, and a major cause of death worldwide. Despite this,...
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AGC1-mediated Metabolic Reprogramming and Autophagy Sustain Survival of Hepatocellular Carcinoma Cells under Glutamine Deprivation
The dependence of hepatocellular carcinoma (HCC) cells on glutamine suggests the feasibility of targeting glutamine metabolism for therapy. However,...
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Ubiquitination-specific protease 7 enhances stemness of hepatocellular carcinoma by stabilizing basic transcription factor 3
This study aims to explore the molecular regulation mechanism of ubiquitination-specific protease 7 (USP7) in facilitating the stemness properties of...
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Adiponectin Receptor Agonist Effectively Suppresses Hepatocellular Carcinoma Growth
Hepatocellular carcinoma (HCC) is the second lethal cancer. Short overall survival, low five-year survival rate, and unimproved treatment efficacy...
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Featured lncRNA-based signature for discriminating prognosis and progression of hepatocellular carcinoma
Long non-coding RNAs (lncRNAs) have been implicated in carcinogenesis and progression of hepatocellular carcinoma (HCC). This study aimed to identify...
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Regulation of Hepatocellular Carcinoma Epithelial-Mesenchymal Transition Mechanism and Targeted Therapeutic Approaches
Hepatocellular carcinoma (HCC) is a primary liver malignancy that accounts for the majority of liver cancer cases, with multiple risk factors...
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Emerging role of MicroRNA-Based theranostics in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC), with its high mortality and short survival rate, continues to be one of the deadliest malignancies despite relentless...
