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Oogenesis and Folliculogenesis
The ovary is a dynamic structure with two main functions. First, the ovary is responsible for producing hormones that control and direct the female...
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Genetic evidence for differential functions of figla and nobox in zebrafish ovarian differentiation and folliculogenesis
FIGLA and NOBOX are important oocyte-specific transcription factors. Both figla-/- and nobox-/- mutants showed all-male phenotype in zebrafish due to...
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Map** putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators
Dynamic epigenomic reprogramming occurs during mammalian oocyte maturation and early development. However, the underlying transcription circuitry...
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The effects of endogenous FSH and its receptor on oogenesis and folliculogenesis in female Alligator sinensis
BackgroundThe precise mechanisms of hormone action responsible for the full course of events modulating folliculogenesis in crocodilian have not been...
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Circadian regulation of mTORC1 signaling via Per2 dependent mechanism disrupts folliculogenesis and oocyte maturation in female mice
mTOR (mammalian target of Rapamycin) is an important signaling pathway involved in several crucial ovarian functions including folliculogenesis and...
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PUMILIO-mediated translational control of somatic cell cycle program promotes folliculogenesis and contributes to ovarian cancer progression
Translational control is a fundamental mechanism regulating animal germ cell development. Gonadal somatic cells provide support and microenvironment...
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Primate-specific POTE-actin gene could play a role in human folliculogenesis by controlling the proliferation of granulosa cells
Patients with primary ovarian insufficiency (POI) often have a high prevalence of autoimmune disorders. To identify antigenic molecules associated...
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The effect of Myo-Inositol supplement on molecular regulation of folliculogenesis, steroidogenesis, and assisted reproductive technique outcomes in patients with polycystic ovarian syndrome
Research questionThe mechanism of Myo-Inositol, as an adjuvant, on key signaling pathways related to oocyte maturation, fertilization rate, and...
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Method of Isolation and In Vitro Culture of Primordial Follicles in Bovine Animal Model
The mammalian ovary is a substantial source of oocytes arranged into follicles at various stages of folliculogenesis, from the primordial to the...
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Oocyte Casein kinase 1α deletion causes defects in primordial follicle formation and oocyte loss by impairing oocyte meiosis and enhancing autophagy in develo** mouse ovary
Casein kinase 1α is a member of CK1 family, which is ubiquitously expressed and plays multiple functions, including its potential roles in regulating...
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From in vivo to in vitro: exploring the key molecular and cellular aspects of human female gametogenesis
Human oogenesis is a highly complex and not yet fully understood process due to ethical and technological barriers that limit studies in the field....
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Mechanistic actions of long non-coding RNA MALAT1 within the ovary and at the feto-maternal interface
Long non-coding RNAs (LncRNAs) are being unveiled as crucial regulators of several biological processes and pathways. Among the lncRNAs is...
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Ovarian expression of follicle stimulating hormone and activin receptors genes in a prenatally-androgenized rat model of polycystic ovary syndrome in adulthood
BackgroundThe expression of genes involved in basic pathways, such as folliculogenesis and steroidogenesis may be affected following prenatal...
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Human theca arises from ovarian stroma and is comprised of three discrete subtypes
Theca cells serve multiple essential functions during the growth and maturation of ovarian follicles, providing structural, metabolic, and...
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Analyzing the cellular and molecular atlas of ovarian mesenchymal cells provides a strategy against female reproductive aging
Ovarian mesenchymal cells (oMCs) constitute a distinct microenvironment that supports folliculogenesis under physiological conditions....
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SRSF1 regulates primordial follicle formation and number determination during meiotic prophase I
BackgroundOvarian folliculogenesis is a tightly regulated process leading to the formation of functional oocytes and involving successive quality...
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ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
BackgroundISGylation is a post-translational protein modification that regulates many life activities, including immunomodulation, antiviral...
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Arsenic-Induced Thyroid Hormonal Alterations and Their Putative Influence on Ovarian Follicles in Balb/c Mice
Thyroid issues are common among women in their reproductive years, and women with thyroid dysfunction often encounter challenges with fertility....
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Sustainable Agriculture Reviews 59 Animal Biotechnology for Livestock Production 3
The dependency on animal biotechnology in livestock industries has been increased in the recent past. The livestock production research has...